Diagnosis and treatment of late jaundice in late preterm and term newborns: An integrative literature review / Diagnóstico e tratamento da icterícia tardia em recém-nascidos prematuros tardios e a termo: Uma revisão integrativa de literatura

Although it is a common clinical condition in neonatology, jaundice must have an adequate diagnosis and an on-time treatment since the excess of bilirubin can lead to the development of kernicterus – that, in rare cases, can lead to neonatal death. This study aimed to identify which diagnostic methods and treatment of late jaundice in late preterm and term show greater relevance, efficacy, and safety. An integrative review was performed through SciELO, Pubmed, and Bireme databases, of publications between 2015 and 2020, using the descriptors "neonatal jaundice", "neonatal hyperbilirubinemia", "neonatal jaundice" and "neonatal hyperbilirubinemia".  After the articles extraction, they were stratified in a dataset, from which 17 articles that deal with the diagnosis and / or treatment of late preterm newborns and / or suitable for gestational age were selected and arranged in narrative and charts. It was possible to establish that although serum bilirubin testing is widely used, extracorporeal methods are a good option in the diagnosis of jaundice, with good accuracy, for which phototherapy is the main treatment. There are effective, safe, and low-cost alternatives for the diagnosis and treatment of neonatal jaundice, that work by minimizing the risks of complications