Manifold dimension of a causal set: Tests in conformally flat spacetimes

This paper describes an approach that uses flat-spacetime dimension estimators to estimate the manifold dimension of causal sets that can be faithfully embedded into curved spacetimes. The approach is invariant under coarse graining and can be implemented independently of any specific curved spacetime. Results are given based on causal sets generated by random sprinklings into conformally flat spacetimes in 2, 3, and 4 dimensions, as well as one generated by a percolation dynamics.Comment: 8 pages, 8 figure

Shaping the future for primary care education and training project. Integrated health and social care: the perspectives of people using services: a mixed methods analysis

The aim of this study was to explore service users' perspectives concerning integrated health & social care, and to identify the perceived strengths and weaknesses associated with the current workforce and services provided. The findings will be used to inform the education and training of the health and social care workforce in the North West of Englan

Design and performance of a high-pressure-ratio, highly loaded axial-flow transonic compressor space

A 50-cm-diam. axial-flow transonic compressor stage with multiple-circular-arc blades was designed and tested. At design speed, a rotor peak efficiency of 0.85 occurred at an equivalent weight flow of 29.3 kg/sec. Stage peak efficiency was 0.79 at 28.6 kg/sec. Stage total pressure ratio at peak efficiency was 1.84. The stall margin at design speed was 5 percent. Rotor and stator losses were higher than predicted. The stator choked at design flow

Effects of reset stators and a rotating, grooved stator hub on performance of a 1.92-pressure-ratio compressor stage

The overall performance and blade-element performance of a transonic fan stage are presented for two modified test configurations and are compared with the unmodified stage. Tests were conducted with reset stators 2 deg open and reset stators with a rotating grooved stator hub. Detailed radial and circumferential (behind stator) surveys of the flow conditions were made over the stable operating range at rotative speeds of 70, 90, and 100 percent of design speed. Reset stator blade tests indicated a small increase in stage efficiency, pressure ratio, and maximum weight flow at each speed. Performance with reset stators and a rotating, grooved stator hub resulted in an additional increase in stage efficiency and pressure ratio at all speeds. The rotating grooved stator hub reduced hub losses considerably

5-micron photometry of late-type dwarfs

We present narrowband-M photometry of nine low-mass dwarfs with spectral types ranging from M2.5 to L0.5. Combining the (L'-M') colours derived from our observations with data from the literature, we find colours consistent with a Rayleigh-Jeans flux distribution for spectral types earlier than M5, but enhanced F_3.8/F_4.7 flux ratios (negative (L'-M') colours) at later spectral types. This probably reflects increased absorption at M' due to the CO fundamental band. We compare our results against recent model predictions and briefly discuss the implications.Comment: accepted for the Astronomical Journa

Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice

Failure to express or expression of dysfunctional low-density lipoprotein receptors (LDLR) causes familial hypercholesterolemia in humans, a disease characterized by elevated blood cholesterol concentrations, xanthomas, and coronary heart disease, providing compelling evidence that high blood cholesterol concentrations cause atherosclerosis. In this study, we used 1H nuclear magnetic resonance spectroscopy to examine the metabolic profiles of plasma and urine from the LDLR knockout mice. Consistent with previous studies, these mice developed hypercholesterolemia and atherosclerosis when fed a high-fat/cholesterol/cholate-containing diet. In addition, multivariate statistical analysis of the metabolomic data highlighted significant differences in tricarboxylic acid cycle and fatty acid metabolism, as a result of high-fat/cholesterol diet feeding. Our metabolomic study also demonstrates that the effect of high-fat/cholesterol/cholate diet, LDLR gene deficiency, and the diet-genotype interaction caused a significant perturbation in choline metabolism, notably the choline oxidation pathway. Specifically, the loss in the LDLR caused a marked reduction in the urinary excretion of betaine and dimethylglycine, especially when the mice are fed a high-fat/cholesterol/cholate diet. Furthermore, as we demonstrate that these metabolic changes are comparable with those detected in ApoE knockout mice fed the same high-fat/cholesterol/cholate diet they may be useful for monitoring the onset of atherosclerosis across animal models

Symmetries of Differential Equations via Cartan's Method of Equivalence

We formulate a method of computing invariant 1-forms and structure equations of symmetry pseudo-groups of differential equations based on Cartan's method of equivalence and the moving coframe method introduced by Fels and Olver. Our apparoach does not require a preliminary computation of infinitesimal defining systems, their analysis and integration, and uses differentiation and linear algebra operations only. Examples of its applications are given.Comment: 15 pages, LaTeX 2.0

Isolation and characterisation of 17 microsatellite loci for the red-billed chough (Pyrrhocorax pyrrhocorax)

Peer reviewedPostprin