20 research outputs found
Shrinking Employees Turnover Intention by applying Tools of Job Embeddedness (Used as a Mediator)
The current research study examined the association among the HRM practices through job embeddedness (as a mediator) and employee turnover intentions. In this study, the researchers used new construct i.e. job embeddedness to explore its mediating impact on the relationship between employee turnover intentions and HRM practices such as training, compensation, career planning, performance appraisal and supervisor support. Job embeddedness was studied in terms of fit, links, and sacrifice organization. Job embeddedness plays a crucial role to reduce turnover. If organization applies these HRM practices in true letter and spirit, then their employees will be more satisfied, committed, and loyal to that organization. If employees are more embedded to the organization in a positive manner, so that employees are more committed, satisfied and impacts their performance
P-SEPARATION AXIOMS IN SUPRA SOFT TOPOLOGICAL SPACE
The central objective of this article is to introduce soft pre P-separations in soft supra topological spaces. We discuss soft P-separations in soft supra topological spaces with respect to ordinary points and soft points. Further study the hereditary properties at different angles with respect to ordinary points as well as with respect to soft points. Some of their fundamental properties in soft supra topological spaces are also reflected
Comparison of Conventional Cyclophosphamide versus Fludarabine-Based Conditioning in High-Risk Aplastic Anemia Patients Undergoing Matched-Related Donor Transplantation
Allogeneic stem cell transplant for high-risk aplastic anemia (AA) yields inferior results using conventional cyclophosphamide (CY)-based conditioning. The use of fludarabine (Flu)-based regimens has resulted in improved outcomes in high-risk patients. Limited data are available comparing these two conditioning regimens in such patients. We retrospectively analyzed 192 high-risk patients undergoing matched-related donor transplantation from July 2001 to December 2018. The median age was 19.5 (2–52) years. Patients were divided into 2 groups, Cy200 anti-thymocyte globulin (ATG)20 (Gp1 n = 79) or Flu120–150 Cy120–160 ATG20 (Gp2 n = 113). The risk of graft failure was significantly higher in Gp1, and the majority occurred in patients with >2 risk factors (p = 0.02). The incidence of grade II-IV acute graft versus host disease (GVHD) and chronic GVHD was not significantly different between the two groups. The overall survival (OS) of the study cohort was 81.3 %, disease-free survival (DFS) 76.6 % and GVHD-free relapse-free survival (GRFS) was 64.1%. DFS and GRFS were significantly higher in Gp2 as compared to Gp1: DFS 84.1% versus 68.4 % (p = 0.02), GRFS 77.9% versus 54.4% (p = 0.01), respectively. We conclude that Flu-based conditioning is associated with superior OS, DFS and GRFS as compared to the conventional Cy-based regimen in high-risk AA
Factors affecting sustainable iodine deficiency elimination in Pakistan: A global perspective
Iodine deficiency remains a considerable challenge worldwide, even after decades of efforts to address the problem. The aim of this review is to present the current situation in historically iodine-deficient Pakistan regarding iodine nutritional status and place it in a global perspective. We collected relevant articles from online bibliographic databases and websites of concerned organizations that addressed prevalence of goiter/iodine deficiency and barriers to sustainable control. We divided the studies into pre- and post-1994, a landmark year when Pakistan formally adopted the universal salt iodization (USI) programme. Overall, 56 studies reported goiter/iodine deficiency prevalence in Pakistan. Before 1994, six studies (30%) reported a goiter prevalence ≥70%, while nine studies (45%) reported a goiter prevalence between 30% and 70%. Only five studies (25%) found a goiter prevalence less than 30%, of which only two studies reported prevalence <10%. From 1994 onwards, 15 studies (41.7%) reported a goiter/iodine deficiency (ID) prevalence ≥50%, of which seven studies reported prevalence ≥70%, while three studies (8.3%) found a goiter prevalence of 30%–49%, nine studies (25%) found a goiter prevalence of 10%–29%, and five studies (13.9%) reported prevalence of <10%. Four studies (11.1%) reported lower goiter prevalence but higher prevalence of iodine deficiency. The efforts in the past two decades resulted in up to a 50% decline in iodine deficiency disorders (IDD). Variable remaining factors and the recent results, however, indicate that this decline may be non-uniform and even over-estimated. Coordinated and regionally adopted efforts for eradication of IDD from all stakeholders should be pursued. Policy makers should take steps to protect future generations and alert concerned organizations about the importance of careful assessments and estimates of iodine nutritional status
Monitoring the prevalence of thyroid disorders in the adult population of Northeast Germany
Abstract Background Only a few studies like ours have investigated the effect of long-term stable iodine supply on thyroid disorders in a historically iodine-deficient population, but not with a long follow-up time of 10 years. Methods Data were derived from two independent population-based cohorts of the Study of Health in Pomerania (SHIP-0 [1997–2001] and SHIP-TREND [2008–2012]) comprising 4308 and 4420 subjects, respectively. Diagnosed thyroid disorders were assessed. Thyroid gland dimensions were examined by ultrasound. Levels of serum thyrotropin (TSH) and autoantibodies to thyroperoxidase (anti-TPO Abs) were measured from blood samples. Results Median urinary iodine excretion levels decreased from 123.0 μg/l to 112.0 μg/l (p = <0.001) between 2000 and 2010. The prevalence of known thyroid disorders increased from 7.6 % [CI 6.9–8.5] to 18.9 % [CI 17.6–20.1] and of thyroid medication use from 6.2 to 11.1 %. The prevalence of goiter decreased from 35.1 to 29.4 % (p = <0.001), while the prevalence of positive anti-TPO Abs decreased from 3.9 to 2.9 % (p = 0.022). Median serum TSH levels increased from 0.69 mIU/L to 1.19 mIU/L (p = <0.001). Consequently, prevalence of high TSH (mIU/L) increased from 2.6 to 2.9 % (p = 0.452), and low TSH (mIU/L) decreased from 6.6 to 6.4 % (p = 0.737). Conclusion The decreased prevalence of iodine-deficient disorders and a stable prevalence of markers of autoimmune thyroid disorders argue for an improved iodine supply of the adult population in Northeast Germany. In contrast, the prevalence of diagnosed thyroid disorders and the intake of thyroid medication increased, although this might be related to inappropriate therapeutic decisions
A Perspective of the Human–Grey Wolf (Canis lupus) Conflicts in Kumrat Valley, Northern Pakistan
In developing countries, long-term conservation goals are hindered by the high economic costs of human–wildlife conflicts. The grey wolf is one of the prominent species indulged in these incidents. We investigated human–wolf conflicts (HWCs) by interviewing 104 respondents from five villages in Kumrat Valley, northern Pakistan. The respondents declared the grey wolf a common and highly dangerous carnivore. The grey wolf was found implicated in livestock predation, inflicting a yearly economic loss of USD 9225 (USD 88.70 per household (with monthly average income of 119 USD)). Our results confirmed that livestock predation was the main reason for the community’s hostile attitude (65.38%) and perception of the grey wolf. Concerning occupation, farmers have the most significant negative attitude (p = 0.040) towards the grey wolf, yet employees (p = 0.025) and students (p = 0.030) showed a positive attitude. In addition, the other factors contributing to the negative attitude towards the grey wolf were the grey wolf sightings and livestock predation (p = 0.016 and p = 0.006), respectively. Based on the findings, we believe that predation compensation and livestock vaccination programs (as done in Gilgit-Baltistan Province of northern Pakistan as a measure of snow leopard conservation, to prevent mass mortalities of livestock due to diseases and in turn safeguarding the predator from retaliatory killing by locals in case of livestock predation) educating the populous can be very promising in minimizing the HWCs in the study area. We also recommend robust and continuous coordination between the local communities and the concerned departments
Is irrigation water free?: a reality check in the Indo-Gangetic Basin
'Getting prices right? is the silver bullet widely advocated to developing countries in fighting waste, misallocation and scarcity of water. In the vast, poverty-stricken Indo-Gangetic basin, however, high surrogate water price is driving out small-holder irrigation. With rising diesel prices, most small-holders who use borewells for irrigation find effective water use cost soaring, obliging them to economize on water use even by quitting irrigated farming. Electrified borewell owners, far fewer, face low marginal cost but have to contend with stringent electricity rationing. Public irrigation systems grossly under-price irrigation, but these are getting marginalized despite massive government and donor investments
A Perspective of the Human–Grey Wolf (<i>Canis lupus</i>) Conflicts in Kumrat Valley, Northern Pakistan
In developing countries, long-term conservation goals are hindered by the high economic costs of human–wildlife conflicts. The grey wolf is one of the prominent species indulged in these incidents. We investigated human–wolf conflicts (HWCs) by interviewing 104 respondents from five villages in Kumrat Valley, northern Pakistan. The respondents declared the grey wolf a common and highly dangerous carnivore. The grey wolf was found implicated in livestock predation, inflicting a yearly economic loss of USD 9225 (USD 88.70 per household (with monthly average income of 119 USD)). Our results confirmed that livestock predation was the main reason for the community’s hostile attitude (65.38%) and perception of the grey wolf. Concerning occupation, farmers have the most significant negative attitude (p = 0.040) towards the grey wolf, yet employees (p = 0.025) and students (p = 0.030) showed a positive attitude. In addition, the other factors contributing to the negative attitude towards the grey wolf were the grey wolf sightings and livestock predation (p = 0.016 and p = 0.006), respectively. Based on the findings, we believe that predation compensation and livestock vaccination programs (as done in Gilgit-Baltistan Province of northern Pakistan as a measure of snow leopard conservation, to prevent mass mortalities of livestock due to diseases and in turn safeguarding the predator from retaliatory killing by locals in case of livestock predation) educating the populous can be very promising in minimizing the HWCs in the study area. We also recommend robust and continuous coordination between the local communities and the concerned departments
Diesel price hike and the energy squeeze on Pakistan's smallholder irrigators
The smallholder irrigators of Pakistan have been under squeeze due to rising energy costs, as they depend heavily on pump and tractor owners for irrigation water and agricultural operations. The recent trends of perpetual increase in the energy prices in general, and diesel prices in particular, have resulted into soaring operational costs of agricultural machinery, causing the pumps and tractor rentals to rise because of monopoly of pump owners in the informal village markets. This paper aims at bringing forth the impacts of successive diesel price increase on irrigation economy of smallholders, and their coping strategies to absorb the energy shocks and sustain their livelihoods. Based on a synthesis of qualitative assessment from 9 village level case studies carried out in NWFP, Punjab and Sindh provinces of Pakistan, where diesel and electric pumps are essential for sustaining irrigated agriculture, the paper confirms that the recent hike in diesel prices have proven to be the proverbial last straw on camel's back for the livelihoods of small farmers and tenants. While some landless tenants had quitted agriculture as a profession due in part to soaring diesel prices, the major coping strategies of the survivors were [a] switching the power source; [b] high input - high profit strategy; c) water conservation strategy; and d) agriculture exodus strategy. The paper also suggests areas for policy intervention and further research
Is Irrigation Water Free? A Reality Check in the Indo-Gangetic Basin
Summary "Getting prices right" is the silver bullet widely advocated to developing countries in fighting waste, misallocation and scarcity of water. In the vast, poverty-stricken Indo-Gangetic basin, however, high surrogate water price is driving out small-holder irrigation. With rising diesel prices, most small-holders who use borewells for irrigation find effective water use cost soaring, obliging them to economize on water use even by quitting irrigated farming. Electrified borewell owners, far fewer, face low marginal cost but have to contend with stringent electricity rationing. Public irrigation systems grossly under-price irrigation, but these are getting marginalized despite massive government and donor investments.Indo-Gangetic basin water pricing water and poverty