2 research outputs found
CD84 expression on human hematopoietic progenitor cells
- Author
- Publication venue
- Publication date
- 01/01/2003
- Field of study
OBJECTIVE: CD84 is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this family have been implicated in the activation of T cells and NK cells. Expression of CD84 was originally described on most mononuclear blood cells as well as platelets. To elucidate its presence on other blood cell types, we analyzed the expression pattern of CD84 on human immature CD34+ and mature hematopoietic cells. METHODS: Expression analysis was carried out by flow cytometry. The differentiation potential of CD84+ progenitor cells was assessed by colony-forming assays and long-term cultures. RT-PCR was used to analyze CD84 mRNA isoforms. RESULTS: In addition to monocytes, macrophages, B cells, and some T cells, CD84 is expressed on the cell surface of the majority of granulocytes. In addition, 64%+/-5% of CD34+ progenitor cells isolated from peripheral blood and 30.5%+/-5% from bone marrow of healthy volunteers also express CD84. The majority of CD34+ cells coexpressing lineage antigens were CD84+. In methylcellulose CD34+CD84+ cells formed primarily erythroid colonies, whereas myeloid or mixed colonies were scarce. The frequency of long-term culture-initiating cells in peripheral blood was approximately fivefold higher in CD34+CD84- vs CD34+CD84+ cells. In short-term cultures, 95% of the initially CD34+CD84- cells became CD84+ after 72 hours. CONCLUSIONS: CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells. The proliferative potential of CD34+ cells decreases with increasing CD84 expression, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells
Quellen- und Literaturverze
- Author
- Adorno Theodor W
- Allgemeine Preußische Staatszeitung Spenersche Zeitung
- Altenburg Oelers
- Alter Peter
- Andres Geisthövel
- Angermüller Rudolph
- Annales Histoire
- Antient Music
- Antient Music
- Antonicek Theophil
- Antonicek Theophil
- Applegate Celia
- Applegate Potter
- Applegate Potter
- Arblaster Anthony
- Arnold Fuhrmeister
- Arnstein Walter L
- Assmann Harth
- Auerbach Jeffrey A
- Aufbegehren
- Augustine Dolores L
- Balet Gerhard E
- Ballantine Christopher
- Banks Paul
- Bashford Cowgill
- Bashford Langley
- Bauer Anton
- Bauer Elisabeth Eleonore
- Bauernkämper Eisenberg
- Baumeister Martin
- Baumol William J
- Bausinger Hermann
- Bayerdörfer Engelhart
- Bayerdörfer Hellmuth
- Bechdolf Ute
- Becker Heinz
- Becker Heinz
- Becker Heinz
- Becker Heinz
- Becker Wolfgang
- Beedell Ann V
- Beethoven-Haus Bonn
- Behne Klaus-Ernst
- Behne Klaus-Ernst
- Behne Kleinen
- Benjamin Walter
- Bennett Susan
- Berdahl Robert M
- Berger Peter L
- Berghoff Hartmut
- Bermbach Udo
- Bermbach Udo
- Bermbach Udo
- Bermbach Udo
- Berner Brix
- Bernius
- Bernius
- Bernius
- Bernstein Leonard
- Bevan Ian
- Biddle Ian
- Biddlecombe George Charles
- Biddlecombe George Charles
- Biefang Epkenhans
- Biefang Epkenhans
- Bisanz Hans
- Bitter-Hübscher Marieluise
- Bitter-Hübscher Marieluise
- Blackbourn David
- Blackbourn David
- Blackbourn David
- Blanning Tim C. W.
- Blaukopf Blaukopf
- Blaukopf Kurt
- Blaukopf Kurt
- Bokina John
- Bollenbeck Georg
- Bonds Mark Evan
- Bora Alfons
- Borchard
- Borchard
- Borchardt Peter
- Borst Otto
- Botstein Leon
- Botstein Leon
- Botstein Leon
- Botstein Leon
- Bourdieu Pierre
- Bourdieu Pierre
- Boyce D. George
- Bradley Arthur
- Brandenburg Sieghard
- Brandt Bettina
- Braun Rudolf
- Braun Rudolf
- Brewer John
- Brewer John
- Brewer John
- Brunn Reulecke
- Brunn Reulecke
- Brusatti Otto
- Buch Esteban
- Buck Elmar
- Budd Malcolm
- Budde Gunilla-Friederike
- Budde Gunilla-Friederike
- Budde Gunilla-Friederike
- Budde Gunilla-Friederike
- Budden Julian
- Budds Michael J
- Buhler Daniel K. L.
- Bulkow Petersen
- Burrows Donald
- Buxbaum Gerda
- Bödeker Hans Erich
- Bödeker Hans Erich
- Bödeker Hans Erich
- Böning Claus
- Bösch Frank
- Canaris Ute
- Canaris Ute
- Cannadine David
- Cannadine David
- Cannadine David
- Carr Jonathan
- Carse Adam
- Carsten Francis L
- Castells Manuel
- Charle Christophe
- Charle Christophe
- Charle Christophe
- Charle Christophe
- Charle Christophe
- Chickering Roger
- Christoff Dimiter
- Ciarlo David M
- Ciompi Luc
- Clayton Herbert
- Cleve Ingeborg
- Cohen Roth
- Colley Linda
- Colls Dodd
- Colls Dodd
- Connor Waker
- Conrad Sebastian
- Conrad Sebastian
- Conrad Sebastian
- Conze Wienfort
- Cook Nicholas
- Cook Nicholas
- Cook Nicholas
- Cooper Barry
- Copland Aaron
- Cople Jaher Frederic
- Corbin Alain
- Covent Garden
- Croll
- Csáky Moritz
- Csáky Moritz
- Cunningham Hugh
- Cunningham Hugh
- Dahlhaus Carl
- Dahlhaus Carl
- Dahlhaus Carl
- Dahlhaus Carl
- Dahlhaus Carl
- Dahlhaus Carl
- Dahlhaus Carl
- Daniel Ute
- Daniel Ute
- Danuser Hermann
- Danuser Hermann
- Danuser Hermann
- Danuser Hermann
- Danuser Hermann
- Danuser Hermann
- Davis Emeljanow
- Davis Natalie Z
- Deathridge John
- Dennis David B
- DeNora Tia
- DeNora Tia
- Deutsch Otto Erich
- Deutsch Walter
- Dewey John
- Dieman Kurt
- Dietrich Margret
- Dilcher Gerhard
- Dollase Rainer
- Dollase Rainer
- Dollase Rainer
- Döcker Ulrike
- Döhring Sieghart
- Döhring Sieghart
- Döhring Sieghart
- Edelman Murray
- Eggebrecht Hans Heinrich
- Eggebrecht Hans Heinrich
- Eghigian Berg
- Ehrlich Cyril
- Ehrlich Cyril
- Eichhorn Andreas
- Eisenstadt Shmuel N
- Eley Geoff
- Elias Norbert
- Elkin Robert
- Ellis Katherine
- Ellsworth Therese
- Elvers Rudolf
- Engraving
- Erbacher Brigitte
- Erickson Raymond
- Evans Richard
- Evans Robert J. W.
- Evans Robert J. W.
- Everist Mark
- Eybl Martin
- Fahrmeir Andreas
- Faul Michel
- Faulstich Werner
- Fauser Annegret
- Fenner Theodor
- Fischer Jens Malte
- Fischer-Lichte Erika
- Floros Constantin
- Forsyth Michael
- François Etienne
- Frevel Bernhard
- Frevel Bernhard
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Frevert Ute
- Freydank Ruth
- Frie Ewald
- Friedländer Rüsen
- Frisch Walter
- Frisch Walter
- Frith Simon
- Frith Simon
- Fryer Paul
- Früchtl Zimmermann
- Fuhrmann Christina
- Fuhrmann Daniel
- Fuhrmann Manfred
- Fulcher Jane F
- Fulcher Jane F
- Fulcher Jane F
- Föllmer Müller
- Gabrielsson Lindström
- Gall Lothar
- Gall Lothar
- Gall Lothar
- Gallé Volker
- Garside Patricia
- Gay Peter
- Gay Peter
- Gebhardt Zingerle
- Geck Martin
- Geck Martin
- Geck Martin
- Geck Martin
- Geertz Clifford
- Gegenwart Bde
- Geisthövel Alexa
- Geisthövel Alexa
- Geisthövel Alexa
- Geisthövel Alexa
- Geppert Gerwarth
- Gerhard Anselm
- Gerhard Anselm
- Gerhards Jürgen
- Gibbs Christopher H
- Gibbs Christopher H
- Gienow-Hecht Jessica C. E.
- Gigerenzer Gerd
- Glatzer Ruth
- Glogner Föhl
- Glogner Föhl
- Glogner-Pilz Patrick
- Goldschmidt Köhler
- Gooley Dana
- Gooley Dana
- Gooley Dana
- Gradenwitz Peter
- Gramit David
- Gramit David
- Grasskamp Walter
- Grazer Wolfgang
- Grebing Helga
- Grey Thomas S
- Griffel Margaret Rose
- Griffiths Dennis
- Grossmann-Vendrey Susanne
- Grossmann-Vendrey Susanne
- Grotjahn Rebecca
- Grotjahn Rebecca
- Gunn Simon
- Gusy Haupt
- Hadamowsky Franz
- Hadamowsky Franz
- Hagan Dorothy Veinus
- Hahn Haejeong Hazel
- Hall McClelland
- Hall Peter
- Hall-Witt Jennifer L
- Hall-Witt Jennifer L
- Hall-Witt Jennifer L
- Hall-Witt Jennifer L
- Hamann Brigitte
- Hamann Brigitte
- Hans-Joachim Hinrichsen
- Hans-Joachim Hinrichsen
- Hans-Joachim Hinrichsen
- Hanson Alice M
- Hanson Alice M
- Hardtwig Wehler
- Harnoncourt Nikolaus
- Harris Jose
- Haupt Heinz-Gerhard
- Haupt Heinz-Gerhard
- Haupt Heinz-Gerhard
- Haupt Heinz-Gerhard
- Haupt Heinz-Gerhard
- Haupt Heinz-Gerhard
- Hauser-Schäublin Dickhardt
- Haymarket Theatre
- Hays Michael
- Heartz Wade
- Hein Schulz
- Hein Schulz
- Hein Schulz
- Heinemann Hinrichsen
- Heister Hanns-Werner
- Heister Hanns-Werner
- Hellsberg Clemens
- Hennion Antoine
- Hennion Antoine
- Henscheid Eckhard
- Hentschel Frank
- Henzel Christoph
- Herbert Trevor
- Herrmann-Schneider Hildegard
- Herzfeld Hans
- Hesse Hermann
- Hettling Hoffmann
- Hettling Hoffmann
- Hildebrand Klaus
- Hirsch Bernd
- Hirschfeld Robert
- Hobsbawm Eric J
- Hobsbawm Eric J
- Hobsbawm Eric J
- Hobsbawm Eric J
- Hobsbawm Eric J
- Hochschild Arlie A
- Hook Holger
- Hopkins Porter Cecilia
- Hoppen K. Theodore
- Houghton Walter E
- Hughes Stradling
- Hughes Stradling
- Hughes Stradling
- Huizinga Johan
- Hutcheon
- Hyman Ronald
- Höhne Steffen
- Hübscher Marieluise
- Hüttner Johann
- Hüttner Johann
- Irving Howard
- Isherwood Robert M
- Jacobs Arthur
- Jacobshagen Reininghaus
- Jahn Michael
- Jahn Michael
- Janik Allan
- Jauß Hans Robert
- Jefferies Matthew
- John Eckhard
- John Parry
- Johnson James H
- Jones Wahrman
- Joppig Gunther
- Joyce Patrick
- Jung Ute
- Juslin Patrik N
- Kaden Christian
- Kaelble Hartmut
- Kaelble Hartmut
- Kaiser Kaiser
- Kalbeck
- Kannonier Reinhard
- Karnes Kevin
- Karpenstein-Eßbach Christa
- Kaschuba Wolfgang
- Kater Michael H
- Kelly Thomas Forrest
- Kemp Wolfgang
- Kerr Cameron David
- Kersting Ann
- Kessel Martina
- Kill Susanne
- King W. Davies
- Kitson Richard
- Klenke Dietmar
- Knepler Georg
- Knif Henrik
- Knittel K. M.
- Knoblauch Hubert
- Knoch Morat
- Kocka Jürgen
- Kocka Jürgen
- Kocka Jürgen
- Kocka Jürgen
- Kocka Jürgen
- Kocka Jürgen
- Koegler Siegfried Enkelmann
- Kohl Karl-Heinz
- Kohlrausch Martin
- Kohlrausch Martin
- Kondratowitz Hans-Joachim
- Konold Wulf
- Konzerthaus Berlin
- Korff Rürup
- Koselleck Reinhart
- Koselleck Reinhart
- Koselleck Reinhart
- Koselleck Reinhart
- Koselleck Reinhart
- Koselleck Reinhart
- Koselleck Reinhart
- Koury Daniel
- Kořalka Jiří
- Krabbe Wolfgang R
- Kracauer Siegfried
- Kramer Lawrence
- Kraus Dorothea
- Kreutzer Hans Joachim
- Kreuzer Gundula
- Kroen Sheryl
- Krones Hartmut
- Kropfinger Klaus
- Kross Siegfried
- Kundrus Birthe
- Kundrus Birthe
- Körner Axel
- Kühn Hellmut
- Kühn Hellmut
- Kümmel Werner Friedrich
- Küster Konrad
- Lange Hans
- Langer Arne
- Langewiesche Dieter
- Langley Leane
- Large David C
- Layton Robert
- Layton Robert
- Lebrecht Norman
- Leppert McClary
- Leppert McClary
- Leppert McClary
- Leppert McClary
- Leppert McClary
- Lepsius M. Rainer
- Levine Lawrence W
- Levinson Jerrold
- Levy David Benjamin
- Lietzmann Hans J
- Lieven Dominic
- Linke Angelika
- Linke Angelika
- Lipp Carola
- Lissa Zofia
- Locke Ralph P
- Longyear Rey M
- Loo Reijen
- Loos Helmut
- Luhmann Niklas
- Lynch James J
- Maase Kaspar
- MacDonald Miell
- Macfie Alexander L
- MacKenzie John M
- MacKenzie John M
- MacKenzie John M
- MacKenzie John M
- Mahling Christoph-Hellmut
- Mahling Christoph-Hellmut
- Mahling Christoph-Hellmut
- Mahling Christoph-Hellmut
- Mahling Christoph-Hellmut
- Mahling Christoph-Hellmut
- Mandling Peter
- Massie Robert K
- Matthes Isabel
- Matthew James E
- Mauser Siegfried
- Mauser Siegfried
- Mayer Preimesberger
- McCaskie T. C.
- McClary Susan
- McColl Sandra
- McDonald Jan
- McVeigh Simon
- McVeigh Simon
- McVeigh Simon
- McVeigh Simon
- McVeigh Simon
- McVeigh Simon
- McVeigh Simon
- Mergel Thomas
- Mergel Thomas
- Mergel Thomas
- Metropole London
- Meyer Leonard B
- Meyer Stephen C
- Meyer-Hanno Andreas
- Mikoletzky Juliane
- Miller Norbert
- Miller Norbert
- Mitchell Leslie
- Mommsen
- Mommsen
- Mommsen
- Morat Daniel
- Morgan Marjorie
- Morris James M
- Morrow Mary Sue
- Mosse George L
- Motte-Haber
- Motte-Haber
- Motte-Haber
- Muck Peter
- Möckl Karl
- Möckl Karl
- Möhrmann Renate
- Möller Frank
- Müller Jürgen
- Müller Matthias
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Sven Oliver
- Müller Ursula
- Münch Richard
- Münkler Herfried
- Münkler Herfried
- Münkler Herfried
- Naegele Verena
- Neubauer John
- Neuhoff Hans
- Newey Katherine
- Newsome David
- Nietzsche Friedrich
- Nietzsche Friedrich
- Nipperdey Thomas
- Nipperdey Thomas
- Nolte Hettling
- Norris Christoher
- Nowak Adolf
- Obermaier Walter
- Oexle Otto Gerhard
- Olsen Donald J
- Ormay Imre
- Oster Ernst
- Oster Ernst
- Osterhammel Jürgen
- Osterhammel Jürgen
- Osterhammel Jürgen
- Ottlová Pospísil
- Otto Werner
- Paddison Max
- Pao Angela C
- Parker Roger
- Partsch Erich Wolfgang
- Pasler Jann
- Pasler Jann
- Patureau Frédérique
- Paulmann Johannes
- Paulmann Johannes
- Pearsall Ronald
- Perugini Mark Edward
- Pettenkofer Andreas
- Peyser Joan
- Philippi Hans
- Planyavsky Alfred
- Plato Präsentierte Geschichte
- Plunkett John
- Pople Anthony
- Porter Andrew
- Prawy Marcel
- Preimesberger Hella
- Press Volker
- Preußner Eberhard
- Pugh Martin
- Puhle Hans
- Puhle Hans
- Pulzer Peter
- Quander Georg
- Radkau Joachim
- Rebellato Dan
- Reden-Dohna Melville
- Rehm Jürgen
- Reichardt Sven
- Reinermann Lothar
- Remarque Erich Maria
- Rendell Jane
- Retallack James
- Rhein Stefanie
- Ribbe Wolfgang
- Richards Thomas
- Riethmüller Albrecht
- Riggert Ellen
- Ringer Alexander L
- Ringer Alexander L
- Ringer Alexander L
- Rollka Bodo
- Romantic Imagination
- Rosendorfer Herbert
- Rosenthal Harold
- Rosenthal Harold
- Ross Alex
- Ross Peter
- Rowell George
- Rowell George
- Rummenhöller Peter
- Rumpler Helmut
- Ruppert Wolfgang
- Ruppert Wolfgang
- Rushton Julian
- Russell Dave
- Röhl John C. G.
- Röhl John C. G.
- Rösing Helmut
- Rösing Helmut
- Rösing Helmut
- Rösing Helmut
- Rürup Reinhard
- Sachs Joel
- Said Edward W
- Salmen Walter
- Samson Jim
- Samson Jim
- Samson Jim
- Samson Jim
- Samson Jim
- Scheer Monique
- Schirmer Lothar
- Schleuning Peter
- Schmidt-Hensel Roland
- Schmitt Anke
- Schmitt Ulrich
- Schmitt-Thomas Reinhold
- Schmitt-Thomas Reinhold
- Schneer Jonathan
- Schneider Ute
- Schneider Wolfgang
- Scholes Percy A
- Schrenk Oswald
- Schroeder David P
- Schröder Hans-Christoph
- Schueller Herbert M
- Schulin Karin
- Schultze Johanna
- Schutte Sabine
- Schwab Heinrich W
- Schwanitz Dietrich
- Schwengelbeck Matthias
- Schölch Alexander
- Scott Derek B
- Scott Derek B
- Scott Derek B
- Seebohm Andrea
- Sehsucht
- Sennett Richard
- Sessa Anne Dzamba
- Sheehan James J
- Shepherd John
- Shepherd John
- Siegrist Hannes
- Siegrist Hannes
- Sievernich Budde
- Sigsworth Eric M
- Simon Stefan
- Skinner Burrhus F
- Slatin Sonia
- Small Christopher
- Smith Woodruff D
- Soeffner Tänzler
- Soeffner Tänzler
- Solie Ruth A
- Sonnenschein Ulrich
- Sorba Carlotta
- Spaepen Bruno
- Sperber Jonathan
- Sponheuer Bernd
- Spree Ulrike
- Stachel Peter
- Stachel Peter
- Stafford Barbara Maria
- Stamm-Kuhlmann Thomas
- Starr S. Frederick
- Steegmann Rieger
- Steinberg Michael P
- Steinberg Michael P
- Steinmetz Willibald
- Steinmetz Willibald
- Steinmetz Willibald
- Steinmetz Willibald
- Stekl Hannes
- Stekl Hannes
- Stekl Hannes
- Stevenson John
- Stiftung Berliner Philharmoniker
- Stollberg-Rilinger Barbara
- Strauß Bernd
- Stähr Wolfgang
- Supicić Ivo
- Szmolyan Walter
- Tadday Ulrich
- Tadday Ulrich
- Taruskin Richard
- Taruskin Richard
- Taylor Ronald
- Tedeschi James T
- Telesko Werner
- Temperley Nicholas
- Temperley Nicholas
- Temperley Nicholas
- Temperley Nicholas
- Teran Jay Robert S
- The Covent Garden Album
- Ther Philipp
- Ther Philipp
- Ther Philipp
- Ther Philipp
- Thompson Edward P
- Thompson F. M. L.
- Thompson Martyn
- Thorau Christian
- Todd R. Larry
- Toelle Jutta
- Toelle Jutta
- Toelle Jutta
- Toews John Edward
- Toews John Edward
- Torralba Francesco
- Trentmann Frank
- Triebel Armin
- Tröndle Martin
- Tschulik Norbert
- Ulm Renate
- Ulm Renate
- Ulm Renate
- Ulm Renate
- Ulm Renate
- Van der Loo Van Reijen
- Van Laak Dirk
- Veblen Thorstein
- Veit Patrice
- Veltzke Veit
- Veltzke Veit
- Vernon James
- Vester Heinz-Günter
- Vondung Klaus
- Voss Egon
- Wagner Bernd
- Wagner Nike
- Waissenberger Robert
- Wallace Robin
- Walter Michael
- Walter Michael
- Walter Michael
- Walther Gerhard
- Walther Gerrit
- Ward Stuart
- Wasson Ellis
- Weber Max
- Weber Max
- Weber Solveig
- Weber William
- Weber William
- Weber William
- Weber William
- Weber William
- Weber William
- Weber William
- Weber William
- Weber William
- Weber William
- Weber William
- Wegman Rob C
- Wehler Hans-Ulrich
- Wehler Hans-Ulrich
- Wehler Hans-Ulrich
- Wehler Hans-Ulrich
- Weiner Marc A
- Welan Manfred
- Welsch Wolfgang
- Welskopp Thomas
- Weltbürger der Musik
- Weltbürger der Musik
- Werner Karl Ferdinand
- Werner Karl Ferdinand
- White Eric Walter
- Whittall Arnold
- Wienfort Monika
- Wiesmann Sigrid
- Wilberg Petra-Hildegard
- Wilberg Rebecca
- Wilderotter Pohl
- Willms Johannes
- Wiora Walter
- Wirsching Andreas
- Wolff Hellmuth Christian
- Wolff Janet
- Woodward Ernest L
- Young Percy M
- Zalfen Sarah
- Zalfen Sarah
- Zalfen Sarah
- Zelinsky Hartmut
- Zemon Davis Natalie
- Zerback Ralf
- Ziemer Hansjakob
- Zimmermann Clemens
- Zimmermann Reiner
- Zoltai Dénes
- Zon Bennett
- Zur Nieden Gesa
- Publication venue
- 'Vandenhoeck & Ruprecht GmbH & Co, KG'
- Publication date
- Field of study