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    Overview of the Parents’ Knowledge, Attitude and Practice of Children Vaccinations: A Systematic Review

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    Background: It is the parents' responsibility to vaccinate their children. As a result, parents' attitudes, knowledge, and beliefs about vaccination are critical because they influence their activities toward timely and full immunization.  Objectives: This systematic review comprehensively investigated the recently published literature on parents’ knowledge regarding children’s vaccination.  Methods: PubMed, SCOPUS, Web of Science, Science Direct, and Google Scholar were systematically searched to include the relevant literature. Rayyan QRCI was used throughout this systematic approach. Results & interpretation: This review included twenty-four studies with a total of 13082 parents, and 70.9% were mothers. Knowledge level about children’s vaccination among parents was significantly related to their fathers' age, education level, women's employment status, and family type. Younger mothers were found to have a higher level of expertise. Good knowledge levels and positive attitudes towards the seasonal influenza vaccine were reported. Good knowledge with caution was reported among parents regarding COVID-19 vaccination. The knowledge about HPV infection and vaccination: All of them reported low vaccination rates and willingness to vaccinate their children. The findings of our study highlight the significance of parental understanding of vaccinations and immunization. Health officials should make additional efforts to promote the benefits of vaccination while emphasizing the risks of non- or late pediatric immunization
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