Geochemical Negative Emissions Technologies: Part I. Review

Over the previous two decades, a diverse array of geochemical negative emissions technologies (NETs) have been proposed, which use alkaline minerals for removing and permanently storing atmospheric carbon dioxide (CO2). Geochemical NETs include CO2 mineralization (methods which react alkaline minerals with CO2, producing solid carbonate minerals), enhanced weathering (dispersing alkaline minerals in the environment for CO2 drawdown) and ocean alkalinity enhancement (manipulation of ocean chemistry to remove CO2 from air as dissolved inorganic carbon). CO2 mineralization approaches include in situ (CO2 reacts with alkaline minerals in the Earth's subsurface), surficial (high surface area alkaline minerals found at the Earth's surface are reacted with air or CO2-bearing fluids), and ex situ (high surface area alkaline minerals are transported to sites of concentrated CO2 production). Geochemical NETS may also include an approach to direct air capture (DAC) that harnesses surficial mineralization reactions to remove CO2 from air, and produce concentrated CO2. Overall, these technologies are at an early stage of development with just a few subjected to field trials. In Part I of this work we have reviewed the current state of geochemical NETs, highlighting key features (mineral resources; processes; kinetics; storage durability; synergies with other NETs such as DAC, risks; limitations; co-benefits, environmental impacts and life-cycle assessment). The role of organisms and biological mechanisms in enhancing geochemical NETs is also explored. In Part II, a roadmap is presented to help catalyze the research, development, and deployment of geochemical NETs at the gigaton scale over the coming decades

Geochemical Negative Emissions Technologies:Part I. Review

Over the previous two decades, a diverse array of geochemical negative emissions technologies (NETs) have been proposed, which use alkaline minerals for removing and permanently storing atmospheric carbon dioxide (CO2). Geochemical NETs include CO2 mineralization (methods which react alkaline minerals with CO2, producing solid carbonate minerals), enhanced weathering (dispersing alkaline minerals in the environment for CO2 drawdown) and ocean alkalinity enhancement (manipulation of ocean chemistry to remove CO2 from air as dissolved inorganic carbon). CO2 mineralization approaches include in situ (CO2 reacts with alkaline minerals in the Earth's subsurface), surficial (high surface area alkaline minerals found at the Earth's surface are reacted with air or CO2-bearing fluids), and ex situ (high surface area alkaline minerals are transported to sites of concentrated CO2 production). Geochemical NETS may also include an approach to direct air capture (DAC) that harnesses surficial mineralization reactions to remove CO2 from air, and produce concentrated CO2. Overall, these technologies are at an early stage of development with just a few subjected to field trials. In Part I of this work we have reviewed the current state of geochemical NETs, highlighting key features (mineral resources; processes; kinetics; storage durability; synergies with other NETs such as DAC, risks; limitations; co-benefits, environmental impacts and life-cycle assessment). The role of organisms and biological mechanisms in enhancing geochemical NETs is also explored. In Part II, a roadmap is presented to help catalyze the research, development, and deployment of geochemical NETs at the gigaton scale over the coming decades

Geochemical Negative Emissions Technologies:Part II. Roadmap

Geochemical negative emissions technologies (NETs) comprise a set of approaches to climate change mitigation that make use of alkaline minerals to remove and/or permanently store carbon dioxide (CO2) as solid carbonate minerals or dissolved ocean bicarbonate ions. This roadmap accompanies the comprehensive review of geochemical NETs by the same authors and offers guidance for the development and deployment of geochemical NETs at gigaton per year (Gt yr.−1) scale. We lay out needs and high-priority initiatives across six key elements required for the responsible and effective deployment of geochemical NETs: (i) technical readiness, (ii) social license, (iii) demand, (iv) supply chains, (v) human capital, and (vi) infrastructure. We put forward proposals for: specific initiatives to be undertaken; their approximate costs and timelines; and the roles that various actors could play in undertaking them. Our intent is to progress toward a working consensus among researchers, practitioners, and key players about initiatives that merit resourcing and action, primarily focusing on the near-term

Geochemical Negative Emissions Technologies: Part II. Roadmap

Geochemical negative emissions technologies (NETs) comprise a set of approaches to climate change mitigation that make use of alkaline minerals to remove and/or permanently store carbon dioxide (CO2) as solid carbonate minerals or dissolved ocean bicarbonate ions. This roadmap accompanies the comprehensive review of geochemical NETs by the same authors and offers guidance for the development and deployment of geochemical NETs at gigaton per year (Gt yr.−1) scale. We lay out needs and high-priority initiatives across six key elements required for the responsible and effective deployment of geochemical NETs: (i) technical readiness, (ii) social license, (iii) demand, (iv) supply chains, (v) human capital, and (vi) infrastructure. We put forward proposals for: specific initiatives to be undertaken; their approximate costs and timelines; and the roles that various actors could play in undertaking them. Our intent is to progress toward a working consensus among researchers, practitioners, and key players about initiatives that merit resourcing and action, primarily focusing on the near-term

In situ genome sequencing resolves DNA sequence and structure in intact biological samples

Understanding genome organization requires integration of DNA sequence and three-dimensional spatial context; however, existing genome-wide methods lack either base pair sequence resolution or direct spatial localization. Here, we describe in situ genome sequencing (IGS), a method for simultaneously sequencing and imaging genomes within intact biological samples. We applied IGS to human fibroblasts and early mouse embryos, spatially localizing thousands of genomic loci in individual nuclei. Using these data, we characterized parent-specific changes in genome structure across embryonic stages, revealed single-cell chromatin domains in zygotes, and uncovered epigenetic memory of global chromosome positioning within individual embryos. These results demonstrate how IGS can directly connect sequence and structure across length scales from single base pairs to whole organisms

Preliminary Design for a Recirculating Induction Accelerator for Heavy Ion Fusion

Substantial savings in size and cost over a linear machine may be achieved in an induction accelerator in which a heavy ion beam makes many ({approximately}50) passes through one or more circular accelerators. We examine a point design for such an accelerator, consisting of four rings. We discuss the consequences of this design on emittance growth, longitudinal instability growth, vacuum requirements, pulser requirements, pulsed-magnet requirements, acceleration schedule, and cost. 3 refs., 1 tab

Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems

Methods for highly multiplexed RNA imaging are limited in spatial resolution and thus in their ability to localize transcripts to nanoscale and subcellular compartments. We adapt expansion microscopy, which physically expands biological specimens, for long-read untargeted and targeted in situ RNA sequencing. We applied untargeted expansion sequencing (ExSeq) to the mouse brain, which yielded the readout of thousands of genes, including splice variants. Targeted ExSeq yielded nanoscale-resolution maps of RNAs throughout dendrites and spines in the neurons of the mouse hippocampus, revealing patterns across multiple cell types, layer-specific cell types across the mouse visual cortex, and the organization and position-dependent states of tumor and immune cells in a human metastatic breast cancer biopsy. Thus, ExSeq enables highly multiplexed mapping of RNAs from nanoscale to system scale