Informe de la Campaña ARGELIA0203-DP para la evaluación de recursos demersales profundos en las costas de Argelia (Mediterráneo Sud-Occidental)

RESUMEN: Del 5 al 24 de marzo de 2003 se llevó a cabo la campaña de prospección pesquera con arrastre de fondo ARGELIA0203-DP en aguas de Argelia, a bordo del B/O Vizconde de Eza. Se realizaron 55 pescas (3 nulas) entre 200 y 800 m de profundidad. Se presentan los resultados de las capturas realizadas en esta campaña y se analizan los índices de abundancia y biomasa de las especies más importantes, por sector y área geográficos y estrato batimétrico, así como su distribución de tallas por sector geográfico y estrato batimétrico. Se comparan los rendimientos y las tallas obtenidos con los de otras campañas realizadas en el Mediterráneo (MEDITS y BALAR)RÉSUME: Rapport de la campagne ARGELIA0203-DP portant evaluation des ressources demersales des côtes Algeriennes (Mediterrane sud-occidental).- Du 05 au 24 Mars 2003, s’est réalisée une campagne de prospection par chalutage du fond ARGELIA0203-DP des côtes Algériennes, abord du B/O Vizconde de Eza. 55 traits de pêche (3 annulées) ont été effectue entre 200 et 800 m de profondeur. Les résultats des captures réalisées durant cette campagne et l’analyse des indices d’abondance et biomasse des espèces les plus importantes sont présentés, par secteur, par aire géographique et strate bathymétrique, ainsi que leurs distributions de tailles par secteur géographique et strate bathymétrique. Les rendements et les tailles obtenus ont fait l’objet d’une comparaison avec les autres campagnes réalisées dans la Méditerranée (MEDITS et BALAR)ABSTRACT: Report of the ARGELIA0203-DP survey for the assessment of the deep-sea demersal resources off Algerian coasts (southwestern Mediterranean).- From March 5th to 24th 2003 the bottom-trawl survey ARGELIA0203-DP was developed in waters off Argelia, on board R/V Vizconde de Eza. Fifty-five hauls (3 null) were carried out between 200 and 800 m depth. The results of the captures obtained during this survey are shown and abundance and biomass indexes of the most important species are analyzed by geographic sector and area, and bathymetric stratum, as their size distribution by geographic sector and bathymetric stratum. Yields and sizes obtained are compared to those from other surveys carried out in the Mediterranean (MEDITS and BALAR)

Informe de la campaña ARGELIA0204 para la evaluación de recursos demersales en las costas de Argelia (Mediterráneo sud-occidental)

RESUMEN: Del 5 de Febrero al 8 de Marzo de 2004 se llevó a cabo la campaña de prospección pesquera con arrastre de fondo ARGELIA0204 en aguas de Argelia, a bordo del B/O Vizconde de Eza. Se realizaron 114 pescas (6 nulas) entre 40 y 760 m de profundidad. Se presentan los resultados de las capturas realizadas en esta campaña y se analizan los índices de abundancia y biomasa de las especies más importantes, así como su distribución de tallas, por sector geográfico y estrato batimétrico. Se comparan los rendimientos y las tallas obtenidos con los de la campaña realizada en 2003 en la misma área y con otras campañas realizadas en el Mediterráneo.RÉSUME: Rapport de la campagne ARGELIA0204 portant évaluation des ressources demersaux des côtes Algériennes (Méditerranée sud-occidental).- Du 05 du Février au 8 du Mars 2004, s’est réalisée une campagne de prospection par chalutage du fond ARGELIA0204 des côtes Algériennes, a bord du B/O Vizconde de Eza. 114 traits de pêche (6 annulées) ont été effectue entre 40 et 800 m de profondeur. Les résultats des captures réalisées durant cette campagne et l’analyse des indices d’abondance et biomasse des espèces les plus importantes sont présentés, par secteur, par aire géographique et strate bathymétrique, ainsi que leurs distributions de tailles par secteur géographique et strate bathymétrique. Les rendements et les tailles obtenus ont fait l’objet d’une comparaison avec les autres campagnes réalisées dans la Méditerranée.ABSTRACT: Report of the ARGELIA0204 survey for the assessment of the deep-sea demersal resources off Algerian coast (south-western Mediterranean).- From 5 February to 8 March 2004 the bottom-trawl survey ARGELIA0204 was developed in waters off Argelia, on board R/V Vizconde de Eza. 114 hauls (6 null) were carried out between 40 and 800 m depth. The results on the captures obtained during this survey are shown and abundance and biomass indexes of the most important species are analyzed by geographic sector and area, and bathymetric stratum, as their size distribution by geographic sector and bathymetric stratum. Yields and sizes obtained are compared to those from other surveys carried out in the Mediterranea

Outcomes of therapeutic plasma exchange in severe autoimmune hemolytic anemia hospitalizations: An analysis of the National Inpatient Sample

BACKGROUND: Autoimmune hemolytic anemia (AIHA) is characterized by humoral and/or cellular immune-mediated hemolysis of red blood cells. The role of therapeutic plasma exchange (TPE) in AIHA is unclear. STUDY DESIGN AND METHODS: We queried the National Inpatient Sample (NIS) for 2002-2019 to identify hospitalizations with the primary diagnosis of AIHA. We included hospitalizations with the highest severity subclass identified by All Patient Refined Disease Related Group (APR-DRG). We used multivariate regression analysis to compare in-hospital mortality and other relevant in-hospital outcomes between hospitalizations that received TPE and those that did not. RESULTS: We identified 255 weighted hospitalizations in the TPE group and 4973 in the control group. Those in the control group were older (median age 67 vs. 48 years, p \u3c .001) and had a higher prevalence of most comorbidities. The TPE group had higher odds of all-cause in-hospital mortality (odds ratio [OR], 1.59; 95% confidence interval [CI], 1.19-2.11). They also had higher rates of many secondary outcomes, including requiring mechanical ventilation, developing circulatory shock, acute stroke, urinary tract infections, intracranial hemorrhage, acute kidney injury, and requiring new hemodialysis. No significant differences were noted in the rates of acute myocardial infarctions, bacterial pneumonia, sepsis/septicemia, thromboembolic events, and other bleeding events. Furthermore, the TPE group had a higher median length of hospital stay (19 vs. 9 days, p \u3c .001). CONCLUSION: Hospitalizations with severe AIHA that received TPE had higher rates of adverse in-hospital outcomes

Outcomes of therapeutic plasma exchange in severe autoimmune hemolytic anemia hospitalizations: An analysis of the National Inpatient Sample

BACKGROUND: Autoimmune hemolytic anemia (AIHA) is characterized by humoral and/or cellular immune-mediated hemolysis of red blood cells. The role of therapeutic plasma exchange (TPE) in AIHA is unclear. STUDY DESIGN AND METHODS: We queried the National Inpatient Sample (NIS) for 2002-2019 to identify hospitalizations with the primary diagnosis of AIHA. We included hospitalizations with the highest severity subclass identified by All Patient Refined Disease Related Group (APR-DRG). We used multivariate regression analysis to compare in-hospital mortality and other relevant in-hospital outcomes between hospitalizations that received TPE and those that did not. RESULTS: We identified 255 weighted hospitalizations in the TPE group and 4973 in the control group. Those in the control group were older (median age 67 vs. 48 years, p \u3c .001) and had a higher prevalence of most comorbidities. The TPE group had higher odds of all-cause in-hospital mortality (odds ratio [OR], 1.59; 95% confidence interval [CI], 1.19-2.11). They also had higher rates of many secondary outcomes, including requiring mechanical ventilation, developing circulatory shock, acute stroke, urinary tract infections, intracranial hemorrhage, acute kidney injury, and requiring new hemodialysis. No significant differences were noted in the rates of acute myocardial infarctions, bacterial pneumonia, sepsis/septicemia, thromboembolic events, and other bleeding events. Furthermore, the TPE group had a higher median length of hospital stay (19 vs. 9 days, p \u3c .001). CONCLUSION: Hospitalizations with severe AIHA that received TPE had higher rates of adverse in-hospital outcomes

Severe childhood autosomal recessive muscular dystrophy with the deficiency of the 50 kDa dystrophin-associated glycoprotein maps to chromosome 13q12

We have recently demonstrated the specific deficiency for the 50 kDa dystrophin-associated glycoprotein (50DAG) in Algerian patients afflicted with severe childhood autosomal recessive muscular dystrophy with DMD-like phenotype (SCARMD). A similar disease affecting Tunisian patients was linked to chromosome 13q but the status of the 50DAG was not investigated. Here we show by linkage analysis of Algerian families that the genetic defect which leads, either directly or indirectly, to the deficiency of the 50DAG in skeletal muscle is localized to the proximal part of chromosome 13q. We have not found any evidence of genetic heterogeneity among the thirteen families studied. It remains to be demonstrated whether the 50DAG gene maps at 13q12, and to determine if it is mutated in this disease

Primary adhalinopathy: a common cause of autosomal recessive muscular dystrophy of variable severity.

Marked deficiency of muscle adhalin, a 50 kDa sarcolemmal dystrophin-associated glycoprotein, has been reported in severe childhood autosomal recessive muscular dystrophy (SCARMD). This is a Duchenne-like disease affecting both males and females first described in Tunisian families. Adhalin deficiency has been found in SCARMD patients from North Africa Europe, Brazil, Japan and North America (SLR & KPC, unpublished data). The disease was initially linked to an unidentified gene on chromosome 13 in families from North Africa, and to the adhalin gene itself on chromosome 17q in one French family in which missense mutations were identified. Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13. We have examined the importance of primary adhalinopathies among myopathies with adhalin deficiency, and describe several additional mutations (null and missense) in the adhalin gene in 10 new families from Europe and North Africa. Disease severity varies in age of onset and rate of progression, and patients with null mutations are the most severely affected