Party Facts: A database of political parties worldwide

Here, we present Party Facts (www.partyfacts.org), a modern online database of political parties worldwide. With this project, we provide a comprehensive database of political parties across time and world regions, link party information from some of the core social science data sets, and offer a platform to link political parties across data sets. An initial list of 4000 core parties in 212 countries is mainly based on four major data sets. The core parties in Party Facts are linked with party information from some of the key social science data sets, currently 26. From these data sets, we have included and linked about 15,000 party observations. Party Facts is an important step in developing a more coherent operationalization of political parties across time and space and a gateway to existing data sets on political parties. It allows answering innovative party research questions that require the combination of multiple data sets

The Manifesto Corpus: a new resource for research on political parties and quantitative text analysis

This article presents a digital, open-access, multilingual, annotated corpus of electoral programs. It complements the recent methodological innovations in (semi-) computerized content analysis by providing a large, standardized text corpus for the political science community. The corpus is based on the collection of the Manifesto Project, which comprises of (at the time of writing) the largest hand-annotated text corpus of electoral programs available. Since 2009 the project’s costly and time-intensive procedure of collecting and coding documents has been fully digitized. As a result, it now provides more than 1800 machine readable documents from 40 different countries. Six hundred of these documents contain content-analyzed annotations at the level of single (quasi-) sentences, which correspond to the Manifesto Project coding scheme. Additionally, the corpus will continually be extended by incorporating new elections and digitizing older documents. The database also provides meta-information for each document (eg. party, election, language, etc.) that allow it to be referenced back to the Manifesto Dataset. The corpus is stored in a standardized format in an online database, and an API and R package (manifestoR) guarantee easy access

Die Ampelkoalition

Nach der Bundestagswahl 2021 kam es in Deutschland zum ersten Mal seit den 1950er-Jahren zu einer Drei-Parteien-Koalition. Was bedeutet das für die politische Repräsentation der Wähler*innen? Und wie wurden die Wahlversprechen in das Regierungsprogramm übersetzt? Die Autor*innen gehen diesen Fragen sowohl allgemein als auch für vier zentrale Politikfelder (Verkehrswende, Bildungsgerechtigkeit, Familie und Beruf, Digitalisierung in der Gesundheitspolitik) nach. Sie untersuchen, was vor den Wahlen versprochen wurde, wie dies Eingang in die Sondierungsgespräche fand und unter welchen Reibungsverlusten es schließlich im Koalitionsvertrag steht

Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis

BACKGROUND AND AIMS Besides well-defined genetic alterations, the dedifferentiation of mature acinar cells is an important prerequisite for pancreatic carcinogenesis. Acinar-specific genes controlling cell homeostasis are extensively downregulated during cancer development; however, the underlying mechanisms are poorly understood. Now, we devised a novel in vitro strategy to determine genome-wide dynamics in the epigenetic landscape in pancreatic carcinogenesis. DESIGN With our in vitro carcinogenic sequence, we performed global gene expression analysis and ChIP sequencing for the histone modifications H3K4me3, H3K27me3 and H2AK119ub. Followed by a comprehensive bioinformatic approach, we captured gene clusters with extensive epigenetic and transcriptional remodelling. Relevance of Ring1b-catalysed H2AK119ub in acinar cell reprogramming was studied in an inducible Ring1b knockout mouse model. CRISPR/Cas9-mediated Ring1b ablation as well as drug-induced Ring1b inhibition were functionally characterised in pancreatic cancer cells. RESULTS The epigenome is vigorously modified during pancreatic carcinogenesis, defining cellular identity. Particularly, regulatory acinar cell transcription factors are epigenetically silenced by the Ring1b-catalysed histone modification H2AK119ub in acinar-to-ductal metaplasia and pancreatic cancer cells. Ring1b knockout mice showed greatly impaired acinar cell dedifferentiation and pancreatic tumour formation due to a retained expression of acinar differentiation genes. Depletion or drug-induced inhibition of Ring1b promoted tumour cell reprogramming towards a less aggressive phenotype. CONCLUSIONS Our data provide substantial evidence that the epigenetic silencing of acinar cell fate genes is a mandatory event in the development and progression of pancreatic cancer. Targeting the epigenetic repressor Ring1b could offer new therapeutic options

Electromagnetic Field Effect or Simply Stress? Effects of UMTS Exposure on Hippocampal Longterm Plasticity in the Context of Procedure Related Hormone Release

Harmful effects of electromagnetic fields (EMF) on cognitive and behavioural features of humans and rodents have been controversially discussed and raised persistent concern about adverse effects of EMF on general brain functions. In the present study we applied radio-frequency (RF) signals of the Universal Mobile Telecommunications System (UMTS) to full brain exposed male Wistar rats in order to elaborate putative influences on stress hormone release (corticosteron; CORT and adrenocorticotropic hormone; ACTH) and on hippocampal derived synaptic long-term plasticity (LTP) and depression (LTD) as electrophysiological hallmarks for memory storage and memory consolidation. Exposure was computer controlled providing blind conditions. Nominal brain-averaged specific absorption rates (SAR) as a measure of applied mass-related dissipated RF power were 0, 2, and 10 W/kg over a period of 120 min. Comparison of cage exposed animals revealed, regardless of EMF exposure, significantly increased CORT and ACTH levels which corresponded with generally decreased field potential slopes and amplitudes in hippocampal LTP and LTD. Animals following SAR exposure of 2 W/kg (averaged over the whole brain of 2.3 g tissue mass) did not differ from the sham-exposed group in LTP and LTD experiments. In contrast, a significant reduction in LTP and LTD was observed at the high power rate of SAR (10 W/kg). The results demonstrate that a rate of 2 W/kg displays no adverse impact on LTP and LTD, while 10 W/kg leads to significant effects on the electrophysiological parameters, which can be clearly distinguished from the stress derived background. Our findings suggest that UMTS exposure with SAR in the range of 2 W/kg is not harmful to critical markers for memory storage and memory consolidation, however, an influence of UMTS at high energy absorption rates (10 W/kg) cannot be excluded

Wollen wir uns streiten? Zur Legitimität von Konflikt und Kooperation im Parlament

Wieviel Konflikt, wieviel Kooperation wünschen sich die Bürgerinnen in Deutschland von ihrem Parlament? Die institutionellen Rahmenbedingungen und das Verhalten von Oppositions- und Regierungsparteien sind im Deutschen Bundestag eher konsensual-kompromissorientiert ausgeprägt. Allerdings gibt es nur unzureichende Erkenntnisse, inwiefern dies mit den Erwartungen der Bürgerinnen und damit auch dem Grad an politischer Legitimität übereinstimmt. Die Analyse von drei Erwartungsaspekten anhand von Umfragedaten sorgt hier für Aufschluss: Was ist die gewünschte Machtstärke der Opposition? Wie kritisch oder mitarbeitend soll die Opposition sich verhalten? Wie kompromissbereit sollten Parteien in Koalitionen sein? Bezüglich der Stärke und des Verhaltens der Opposition nimmt die Bevölkerung im Schnitt eine eher konsensual-orientierte Erwartungshaltung ein. Im Hinblick auf intra-koalitionäre Entscheidungsfindungsprozesse tritt eine eher majoritär-konfliktuelle Einstellung zutage. Dabei zeigen sich aber auch Unterschiede nach Parteipräferenzen. Die Anhängerinnen der ,echten‘ Oppositionsparteien ohne Regierungserfahrung auf Bundesebene – die Linkspartei und in stärkerem Maße die AfD – wünschen sich eine stärkere, kritischere Opposition und betrachten Koalitionskompromisse noch kritischer als die bereits skeptisch eingestellten Anhängerinnen der anderen Parteien. Diese sich andeutende Polarisierung in den Erwartungshaltungen der Bürgerinnen, aber auch die von der Mehrheit der Bürgerinnen geteilte Forderung nach der Durchsetzung von Parteipositionen auf Kosten von Koalitionskompromissen stellen die Legitimität der derzeit in Deutschland praktizierten Demokratie unter Spannung

Party Facts – Version 2018

Party Facts links datasets on political partie