Seaweeds

Research works oti various aspects of seaweeds have been caried out since last five decades. They inchide resources survey, studies on distribution, Uixonomy, ecology, biology, phycocolioids, biochemicals, culture and utilisation of marine algae growing in Tamil Nadu, Kercda, Lakshadwe^p and Andaman-Nicobar Islands. Information was also gathered since 1978 on the quantity of seaweeds commercially exploited from the natural seaweed beds occurring in Tamil Nadu coast. The results obtained on these aspects are reviewed in this paper. The prospects of seaweed research, industry and utilisation in India are also briefly described

Gender Mainstreaming and Impact of Self Help Groups in Marine Fisheries Sector

Fisheries sector provides employment to over 12 million people and plays a paramount role in Indian economy. Women constitute nearly half of the population and one third of the labour force. Though women’s role in Indian marine fisheries sector with a coast line of 8129 km is very prominent, there is generally a gender bias in respect of their works and the inequalities between men and women are observed in the social, cultural and economic lives. The development and empowerment of weaker sections and gender mainstreaming in the Indian fisheries sector in a broader visualization will be materialized to a substantial extent with poverty eradication programmers through the transparent media namely Self Help Groups (SHGs). However an indepth analysis of the impact of SHGs in bringing out gender mainstreaming was lacking in the present scenario of Indian marine fisheries sector. Integrating gender perspective in SHG ventures in marine fisheries sector is inevitable because the gender mainstreaming approach advances gender equity and equality in the fisheries fabric of the society

Interleukin-10 Producing Regulatory B Cells Transformed CD4+CD25− Into Tregs and Enhanced Regulatory T Cells Function in Human Leprosy

Regulatory B cells (Bregs) are known to exhibit their regulatory functions through interleukin-10 (IL-10) cytokine which suppress inflammation. There are only a few studies explaining the phenotype and functioning of these cells in contribution to host immunity in leprosy. Here, we evaluated the role of IL-10 producing Bregs in the pathogenesis of leprosy and assessed their immunoregulatory effects on Tregs and effector T cells. We found an increased frequency of Bregs and increased expression of their immune modulatory molecules (IL-10, FoxP3, and PDL-1) in leprosy patients. The potential immunoregulatory mechanism of Bregs was also investigated using MACS sorted Teff (CD4+CD25−) and Treg (CD4+CD25+) cells were cocultured with Bregs to elucidate the effects of Bregs on effector T and regulatory T cells. Cell coculture results showed that purified Bregs cells from leprosy patients convert CD4+CD25− cells into CD4+CD25+ cells. Cell coculture experiments also demonstrated that leprosy derived IL-10 producing Bregs enhance FoxP3 and PD-1 expression in Tregs and enhanced Tregs activity. Blocking of IL-10 receptor confirmed that IL-10 producing Breg has immunomodulatory effect on Tregs and effector T cells as effector T cells are not converted into Tregs and enhanced expression of FoxP3 and PD-1 was not observed on Tregs. Collectively, these findings demonstrate that IL-10 producing Breg cells play an important mechanism in controlling the immunopathogenesis of leprosy and have an immunomodulatory effect on Tregs and effector T cells. Our findings may pave way for novel targets of IL-10 producing Bregs for immunotherapy in leprosy patients

The paradigm of gender mainstreaming and impact of SHGs in Indian fisheries sector: an ephemeral depiction

A study was made on the impact of 1000 selected ‘Self Help Groups’ (SHGs) in gender mainstreaming in marine fisheries sector. Their level of performance and extent of empowerment were assessed through appropriate indices of measurement based on data from SHGs of 30 different fishery based micro enterprises from 5 maritime states of India such as Kerala, Karnataka, Tamil Nadu, Andhra Pradesh and Odisha. The gender analysis and economic feasibility analysis based on personal interview and focus group interaction meetings with members of SHGs were undertaken. The male and female counterparts of the families of respondents were separately interviewed to assess the gender mainstreaming impact in terms of equity and equality to access and control over the resources, participation profile, decision making, gender need analysis etc. Analysis of data was essentially done with descriptive statistics such as mean, frequency, percentages, etc. As practical extension part, organized 250 fisherfolk interaction meetings and imparted 100 Entrepreneurial Capacity Building (ECB) Training programmes for the SHGs on the identified micro enterprises by HRD intervention programmes. The major micro enterprises of the SHGs studied were cage culture, bivalve farming, fish aggregating devices, Chinese dip net, clam processing, fish fertilizer, fish amino acid, fish drying, seaweed culture, aqua tourism, seafood kitchen, value addition, fish vending, fish marketing, ornamental fish, ready to eat and cook items, fish feed, aquaponics etc. Economic Feasibility analysis was done for the fishery based micro enterprises accomplished by SHGs and developed Business Plans of the microenterprises representing the indicative economics projecting the break even and payback period of micro-enterprises. Documented 100 success cases on ECB of SHGs with special reference to gender perspective. Brought out 25 video documentaries as Gender Mainstreaming series on Impact of SHGs in Marine Fisheries Sector as success case studies elucidated which can be used as case model for promoting group action and as a practical manual for mobilizing SHGs in any key areas on a sustainable basis

Factors associated with infant mortality in Nepal: a comparative analysis of Nepal demographic and health surveys (NDHS) 2006 and 2011

Background: Infant mortality is one of the priority public health issues in developing countries like Nepal. The infant mortality rate (IMR) was 48 and 46 per 1000 live births for the year 2006 and 2011, respectively, a slight reduction during the 5 years’ period. A comprehensive analysis that has identified and compared key factors associated with infant mortality is limited in Nepal, and, therefore, this study aims to fill the gap. Methods: Datasets from Nepal Demographic and Health Surveys (NDHS) 2006 and 2011 were used to identify and compare the major factors associated with infant mortality. Both surveys used multistage stratified cluster sampling techniques. A total of 8707 and 10,826 households were interviewed in 2006 and 2011, with more than 99% response rate in both studies. The survival information of singleton live-born infants born 5 years preceding the two surveys were extracted from the ‘childbirth’ dataset. Multiple logistic regression analysis using a hierarchical modelling approach with the backward elimination method was conducted. Complex Samples Analysis was used to adjust for unequal selection probability due to the multistage stratified cluster-sampling procedure used in both NDHS.Results: Based on NDHS 2006, ecological region, succeeding birth interval, breastfeeding status and type of delivery assistance were found to be significant predictors of infant mortality. Infants born in hilly region (AOR = 0.43, p = 0.013) and with professional assistance (AOR = 0.27, p = 0.039) had a lower risk of mortality. On the other hand, infants with succeeding birth interval less than 24 months (AOR = 6.66, p = 0.001) and those who were never breastfed (AOR = 1.62, p = 0.044) had a higher risk of mortality. Based on NDHS 2011, birth interval (preceding and succeeding) and baby’s size at birth were identified to be significantly associated with infant mortality. Infants born with preceding birth interval (AOR = 1.94, p = 0.022) or succeeding birth interval (AOR = 3.22, p = 0.002) shorter than 24 months had higher odds of mortality while those born with a very large or larger than average size had significantly lowered odds (AOR = 0.17, p = 0.008) of mortality. Conclusion: IMR and associated risk factors differ between NDHS 2006 and 2011 except ‘succeeding birth interval’ which attained significant status in the both study periods. This study identified the ecological region, birth interval, delivery assistant type, baby’s birth size and breastfeeding status as significant predictors of infant mortality

Curcumin Enhances Neurogenesis and Cognition in Aged Rats: Implications for Transcriptional Interactions Related to Growth and Synaptic Plasticity

Background: Curcumin has been demonstrated to have many neuroprotective properties, including improvement of cognition in humans and neurogenesis in animals, yet the mechanism of such effects remains unclear. Methodology: We assessed behavioural performance and hippocampal cell proliferation in aged rats after 6- and 12-week curcumin-fortified diets. Curcumin enhanced non-spatial and spatial memory, as well as dentate gyrate cell proliferation as compared to control diet rats. We also investigated underlying mechanistic pathways that might link curcumin treatment to increased cognition and neurogenesis via exon array analysis of cortical and hippocampal mRNA transcription. The results revealed a transcriptional network interaction of genes involved in neurotransmission, neuronal development, signal transduction, and metabolism in response to the curcumin treatment. Conclusions: The results suggest a neurogenesis- and cognition-enhancing potential of prolonged curcumin treatment i

Kinome Profiling Reveals an Interaction Between Jasmonate, Salicylate and Light Control of Hyponastic Petiole Growth in Arabidopsis thaliana

Plants defend themselves against infection by biotic attackers by producing distinct phytohormones. Especially jasmonic acid (JA) and salicylic acid (SA) are well known defense-inducing hormones. Here, the effects of MeJA and SA on the Arabidopsis thaliana kinome were monitored using PepChip arrays containing kinase substrate peptides to analyze posttranslational interactions in MeJA and SA signaling pathways and to test if kinome profiling can provide leads to predict posttranslational events in plant signaling. MeJA and SA mediate differential phosphorylation of substrates for many kinase families. Also some plant specific substrates were differentially phosphorylated, including peptides derived from Phytochrome A, and Photosystem II D protein. This indicates that MeJA and SA mediate cross-talk between defense signaling and light responses. We tested the predicted effects of MeJA and SA using light-mediated upward leaf movement (differential petiole growth also called hyponastic growth). We found that MeJA, infestation by the JA-inducing insect herbivore Pieris rapae, and SA suppressed low light-induced hyponastic growth. MeJA and SA acted in a synergistic fashion via two (partially) divergent signaling routes. This work demonstrates that kinome profiling using PepChip arrays can be a valuable complementary ∼omics tool to give directions towards predicting behavior of organisms after a given stimulus and can be used to obtain leads for physiological relevant phenomena in planta

Preliminary estimates of potential areas for seaweed farming along the Indian coast

India has enormous potential for seaweed mariculture; however, mass scale commercial farming of seaweeds is yet to take off successfully in the country. R&D efforts over the years have resulted in techno-scientific improvements in farming technologies such as floating rafts, net-tubes, long-lines, and cage based IMTA systems for seaweed culture. However, a few challenges remain, particular in identifying potential sites, its demarcation and developing suitable and sustainable spatial plans for seaweed farming on a country-wide, commercial perspective. In view of the emerging importance of seaweed mariculture and policy thrust by the Government of India, an all India preliminary site selection survey suitable for seaweed farming was conducted by ICAR-CMFRI along all maritime states of India. From this survey a total of 23,970 ha area were identified as potential seaweed farming along the Indian coast. In the present article, we present details of the suitable sites and its demarcation on a preliminary spatial map for facilitating the imminent expansion and effective adoption of seaweed farming in the country