What can we learn about age-related macular degeneration from other retinal diseases?

Age-related macular degeneration (AMD) is increasingly recognized as a complex genetic disorder in which one or more genes contribute to an individual's susceptibility for developing the condition. Twin and family studies as well as population-based genetic epidemiologic methods have convincingly demonstrated the importance of genetics in AMD, though the extent of heritability, the number of genes involved, and the phenotypic and genetic heterogeneity of the condition remain unresolved. The extent to which other hereditary macular dystrophies such as Stargardts disease, familial radial drusen (malattia leventinese), Best's disease, and peripherin/RDS-related dystrophy are related to AMD remains unclear. Alzheimer's disease, another late onset, heterogeneous degenerative disorder of the central nervous system, offers a valuable model for identifying the issues that confront AMD genetics

The Political Economy of the Russian Industry

This study examines certain changes made within the Russian newspaper industry both before and after the political transformations occurring in the former Soviet Union. Although these changes began after Gorbachev came to power, the most dramatic changes took place after the collapse of the Soviet Union. The political economy perspective provides a useful means to explain the relation between these socioeconomic transitions and the newspaper industry. Since the failed coup of August 1991, the Russian media have attempted to adapt to conditions persistent with the free market economy. As a result of the free market economy, the Russian newspaper industry currently tends to depend on advertising revenue for survival.