Влияние лазерного отжига на структуру, оптические и электрические свойства тонких пленок оксида цинка

Paper presents experimental results of research of influence of laser annealing on the optical and electrical properties ZnO films. Developed technological regimes of modifications of layers in the production of thin film solar modules.Представлены результаты исследования влияния лазерного отжига пленок оксида цинка на их оптические и электрические характеристики. Отработаны технологические режимы модификации слоев для использования в производстве тонкопленочных солнечных модулей

Особенности функционирования жидкокристаллических ячеек с введенными наночастицами CoFe2O4

The first experimental results on the functioning of liquid crystal cells doped with CoFe2O4 nanoparticles are presented. Transmission spectra in the visible and near-infrared range, dynamic parameters of the Fredericks effect, refractive characteristics, as well as wetting angles of the mesophase sensitized surfaces have been obtained. The measured surfaces were the K8 Crown glass, the conductive ITO and the ITO treated with a surface electromagnetic wave. The experiment was performed in order to establish the prospect of using such reliefs as a novel liquid crystal composite orientator sensitized with CoFe2O4 nanoparticles. A color change of the liquid crystal matrix, its refractive coefficients alterations, and the variation of inclination angle of the sensitized liquid crystal droplets on the considered reliefs were established. The time reaction parameters and the medium relaxation parameters were measured. It was proposed that the liquid crystal composition is a kind of an immersion medium that preserves properties of the introduced nanoparticles, which expands their application scope in optoelectronics and biomedicine.В работе представлены результаты первых экспериментов по функционированию жидкокристаллических ячеек с введенными в мезофазу наночастицами CoFe2O4. Измерены спектры пропускания в видимом и ближнем ИК-диапазоне, динамические параметры по эффекту Фредерикса, рефрактивные характеристики, а также углы смачивания сенсибилизированной мезофазой поверхностей на основе стекла: Крон К8, проводящего покрытия ITO и ITO, обработанного поверхностной электромагнитной волной, – для перспективы использования такового рельефа в качестве ориентанта новой жидкокристаллической среды. Установлено изменение цвета жидкокристаллической матрицы, ее рефрактивных коэффициентов и угла наклона капель сенсибилизированного жидкого кристалла на рассмотренных рельефах; измерены временны́ е параметры реакции и релаксации среды. Предложено, что жидкокристаллическая композиция является своего рода иммерсионной средой, сохраняющей свойства введенных наночастиц, что расширяет области их применения в оптоэлектронике и биомедицине

Двумерная периодическая композитная структура для акустического датчика объемных свойств жидкости

The object of the study is acoustic metamaterial, which is a steel matrix with a periodic two-dimensional system of cylindrical cavities filled with hydrocarbon mixture. The induced resonances of fluid in cylindrical cavities of the periodic structure are studied for application in liquid fuel sensors. Theoretical studies of the structure show the possibility of exciting axisymmetric and spinning resonance modes in it in the frequency range with a high reflection coefficient of the structure, which manifest themselves as windows with a narrow bandwidth. Experimental studies confirm the existence of such resonances, and the asymmetric resonance mode is more evident. Measurements of various mixtures of gasoline and ethanol show that the sensor has significant sensitivity for distinguishing between conventional fuels, gasoline-based mixtures and the presence of additives in standard fuels.Описывается композитная структура, представляющая собой стальную матрицу с периодической двумерной системой цилиндрических отверстий, заполненных углеводородной смесью. Изучены упругие колебания такой периодической структуры для применения в акустических датчиках жидкого топлива. Теоретические исследования композитной структуры показали возможность возбуждать в ней аксиально-симметричные и крутильные резонансные моды в частотном диапазоне с высоким коэффициентом отражения структуры, которые проявляются как окна с узкой полосой пропускания. Экспериментальные исследования подтвердили существование таких резонансных частот с характерными структурами акустических волн, причем аксиально-симметричная резонансная мода оказалась более выраженной. Измерения различных смесей бензина и этанола показывают, что датчик имеет значительную чувствительность для различения обычных видов топлива, смесей на основе бензина и присутствия добавок в стандартных видах топлива

Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

The COVID-19 pandemic has highlighted the urgent need for the identification of new antiviral drug therapies for a variety of diseases. COVID-19 is caused by infection with the human coronavirus SARS-CoV-2, while other related human coronaviruses cause diseases ranging from severe respiratory infections to the common cold. We developed a computational approach to identify new antiviral drug targets and repurpose clinically-relevant drug compounds for the treatment of a range of human coronavirus diseases. Our approach is based on graph convolutional networks (GCN) and involves multiscale host-virus interactome analysis coupled to off-target drug predictions. Cell-based experimental assessment reveals several clinically-relevant drug repurposing candidates predicted by the in silico analyses to have antiviral activity against human coronavirus infection. In particular, we identify the MET inhibitor capmatinib as having potent and broad antiviral activity against several coronaviruses in a MET-independent manner, as well as novel roles for host cell proteins such as IRAK1/4 in supporting human coronavirus infection, which can inform further drug discovery studies.We gratefully acknowledge funding that supported this research support from the Ryerson University Faculty of Science (CNA), as well as funding support in the form of a CIFAR Catalyst Grant (JPJ and CNA), an NSERC Alliance Grant (CNA) and the Ryerson COVID-19 SRC Response Fund award (CNA). BW is partly supported by CIFAR AI Chairs Program. This work was also supported by a Mitacs award (BW), the European Union’s Horizon 2020 research and innovation program under a Marie Sklodowska-Curie grant (ER), by the CIFAR Azrieli Global Scholar program (JPJ), by the Ontario Early Researcher Awards program (JPJ and CNA), and by the Canada Research Chairs program (JPJ). We also thank Dr. James Rini (University of Toronto) for the kind gift of the 9.8E12 antibody used to detect the 229E Spike protein, and Dr. Scott Gray-Owen (University of Toronto) for the kind gift of the NL63 human coronavirus.Peer reviewe

Influence of Laser Annealing on the Structure, Electrical and Optical Properties of Zinc Oxide Thin Films

Paper presents experimental results of research of influence of laser annealing on the optical and electrical properties ZnO films. Developed technological regimes of modifications of layers in the production of thin film solar modules

Two-Dimensional Periodic Composite Structure for Acoustic Sensor of Volumetric Properties of Liquids

The object of the study is acoustic metamaterial, which is a steel matrix with a periodic two-dimensional system of cylindrical cavities filled with hydrocarbon mixture. The induced resonances of fluid in cylindrical cavities of the periodic structure are studied for application in liquid fuel sensors. Theoretical studies of the structure show the possibility of exciting axisymmetric and spinning resonance modes in it in the frequency range with a high reflection coefficient of the structure, which manifest themselves as windows with a narrow bandwidth. Experimental studies confirm the existence of such resonances, and the asymmetric resonance mode is more evident. Measurements of various mixtures of gasoline and ethanol show that the sensor has significant sensitivity for distinguishing between conventional fuels, gasoline-based mixtures and the presence of additives in standard fuels