Stable Frank-Kasper phases of self-assembled, soft matter spheres

Single molecular species can self-assemble into Frank Kasper (FK) phases, finite approximants of dodecagonal quasicrystals, defying intuitive notions that thermodynamic ground states are maximally symmetric. FK phases are speculated to emerge as the minimal-distortional packings of space-filling spherical domains, but a precise quantitation of this distortion and how it affects assembly thermodynamics remains ambiguous. We use two complementary approaches to demonstrate that the principles driving FK lattice formation in diblock copolymers emerge directly from the strong-stretching theory of spherical domains, in which minimal inter-block area competes with minimal stretching of space-filling chains. The relative stability of FK lattices is studied first using a diblock foam model with unconstrained particle volumes and shapes, which correctly predicts not only the equilibrium {\sigma} lattice, but also the unequal volumes of the equilibrium domains. We then provide a molecular interpretation for these results via self-consistent field theory, illuminating how molecular stiffness regulates the coupling between intra-domain chain configurations and the asymmetry of local packing. These findings shed new light on the role of volume exchange on the formation of distinct FK phases in copolymers, and suggest a paradigm for formation of FK phases in soft matter systems in which unequal domain volumes are selected by the thermodynamic competition between distinct measures of shape asymmetry.Comment: 40 pages, 22 figure

Population sub-structure and patterns of quantitative variation among the Gollas of Southern Andhra Pradesh, India

This is the published version, also available here: http://digitalcommons.wayne.edu/humbiol/vol73/iss2/9/.Population substructure and biological differentiation was studied among the Golla, a pastoral caste living in the southern areas of Andhra Pradesh (AP) in India, using 11 anthropometric measurements and 20 quantitative dermatoglyphic variables. The data were collected from a sample of 334 adult males drawn from 30 villages distributed in the Chittoor district of AP, who belonged to 8 endogamous subunits of the same caste. Multiple discriminant analysis of the anthropometrics suggests a highly significant degree of discrimination that is consistent with the microgeographic variations of the groups. In contrast, in different sets of dermatoglyphs discrimination is low and generally inconsistent with both the geographic and ethnohistorical affiliations of the groups. These findings are reflected in the FST value for anthropometry, which is more than double the value of dermatoglyphs. The patterns of gene flow as inferred through the regression of phenotypic variance on the distance of groups from the centroid is not generally consistent with the known backgrounds in the case of either dermatoglyphs or anthropometry. It is concluded that at the level of caste substructure representing the lowest level of population hierarchy, the quantitative variables examined here may not portray a complete picture of the historical process of subdivision. The results of this study are not in congruence with those based on another study of 13 short tandem repeat loci on the same set of populations (Reddy et al. 2001), which may provide better insights into the population structure and history of subdivision that are consistent with the known ethnohistorical backgrounds of the populations

Geometric mismatch of pulmonary and aortic anuli in children undergoing the Ross procedure: Implications for surgical management and autograft valve function

AbstractBackground: There is often substantial mismatch between the diameters of the pulmonary and aortic anuli in young patients with systemic outflow tract disease. To implant the autologous pulmonary valve in the aortic position under such circumstances, it is necessary to adapt the geometry of the systemic outflow tract. The effects of such adaptations on autograft function in children are not well known. Methods: To determine factors predictive of autograft regurgitation, we analyzed 41 cases of children who have undergone the Ross procedure. The diameter of the pulmonary valve was greater (by at least 3 mm) than that of the aortic valve in 20 cases, equal (within 2 mm) in 12 cases, and less (by at least 3 mm) in nine cases, with differences ranging from +10 to –12 mm. In 12 patients with a larger pulmonary anulus, aortoventriculoplasty was used to correct the mismatch. In patients with a larger aortic anulus, the mismatch was corrected by gradual adjustment along the circumference of the autograft, rather than by tailoring of the native aortic anulus. Results: At follow-up (median 31 months), two patients had undergone reoperation on the neoaortic valve for moderate regurgitation. In the remaining 38 cases, autograft regurgitation was as follows: none or trivial in 30, mild in seven, and moderate in one. There was no correlation between regurgitation and age, geometric mismatch, or previous or concurrent procedures. Conclusions: Subtle technical factors that may result in distortion of the valve complex are probably more important determinants of autograft regurgitation than are indication for repair, geometric mismatch, or previous or concomitant outflow tract procedures. Significant mismatch of the semilunar anuli is not a contraindication to the Ross procedure in children. (J Thorac Cardiovasc Surg 1998;115:1255-63

A bright, spatially extended lensed galaxy at z = 1.7 behind the cluster RCS2 032727-132623

We present the discovery of an extremely bright and extended lensed source from the second Red Sequence Cluster Survey (RCS2). RCSGA 032727-132609 is spectroscopically confirmed as a giant arc and counter-image of a background galaxy at $z=1.701$, strongly-lensed by the foreground galaxy cluster RCS2 032727-132623 at $z=0.564$. The giant arc extends over $\sim 38$\,\arcsec and has an integrated $g$-band magnitude of 19.15, making it $\sim 20$ times larger and $\sim 4$ times brighter than the prototypical lensed galaxy MS1512-cB58. This is the brightest distant lensed galaxy in the Universe known to date. Its location in the `redshift desert' provides unique opportunities to connect between the large samples of galaxies known at $z\sim3$ and $z\sim1$. We have collected photometry in 9 bands, ranging from $u$ to $K_s$, which densely sample the rest-frame UV and optical light, including the age-sensitive 4000\AA\ break. A lens model is constructed for the system, and results in a robust total magnification of $2.04 \pm 0.16$ for the counter-image; we estimate an average magnification of $17.2 \pm 1.4$ for the giant arc based on the relative physical scales of the arc and counter-image. Fits of single-component spectral energy distribution (SED) models to the photometry result in a moderately young age, $t = 115 \pm 65$\,Myr, small amounts of dust, $E(B-V) \le 0.035$, and an exponentially declining star formation history with \textit{e}-folding time $\tau = 10-100$\,Myr. After correcting for the lensing magnification, we find a stellar mass of $\log(\mathrm{M}/\mathrm{M}_\odot)=10.0 \pm 0.1$. Allowing for episodic star formation, an underlying old burst could contain up to twice the mass inferred from single-component modeling. This stellar mass estimate is consistent with the average stellar mass of a sample of `BM' galaxies ($1.4 < z < 2.0$) studied by Reddy et al. (2006).Comment: 13 pages, 8 figures, abstract abridge

JWST/NIRSpec Measurements of the Relationships Between Nebular Emission-line Ratios and Stellar Mass at z~3-6

We analyze the rest-optical emission-line ratios of star-forming galaxies at 2.7<=z<6.5 drawn from the Cosmic Evolution Early Release Science (CEERS) Survey, and their relationships with stellar mass (M_*). Our analysis includes both line ratios based on the [NII]6583 feature -- [NII]6583/Ha, ([OIII]5007/Hb)/([NII]6583/Ha) (O3N2), and [NII]6583/[OII]3727 -- and those those featuring alpha elements -- [OIII]5007/Hb, [OIII]5007/[OII]3727 (O_32), ([OIII]4959,5007+[OII]3727)/Hb (R_23), and [NeIII]3869/[OII]3727. Given the typical flux levels of [NII]6583 and [NeIII]3869, which are undetected in the majority of individual CEERS galaxies at 2.7<=z<6.5, we construct composite spectra in bins of M_* and redshift. Using these composite spectra, we compare the relationships between emission-line ratios and M_* at 2.7<=z<6.5 with those observed at lower redshift. While there is significant evolution towards higher excitation (e.g., higher [OIII]5007/Hb, O_32, O3N2), and weaker nitrogen emission (e.g., lower [NII]6583/Ha and [NII]6583/[OII]3727) between z~0 and z~3, we find in most cases that there is no significant evolution in the relationship between line ratio and M_* beyond z~3. The [NeIII]3869/[OII]3727 ratio is anomalous in showing evidence for significant elevation at 4.0<=z<6.5 at fixed mass, relative to z~3.3. Collectively, however, our empirical results suggest that there is no significant evolution in the mass-metallicity relationship at 2.7<=z<6.5. Representative galaxy samples and metallicity calibrations based on existing and upcoming JWST/NIRSpec observations will be required to translate these empirical scaling relations into ones tracing chemical enrichment and gas cycling, and distinguish among the descriptions of star-formation feedback in simulations of galaxy formation at z>3.Comment: 10 pages, 4 figures, ApJL, in pres

JWST/NIRSpec Balmer-line Measurements of Star Formation and Dust Attenuation at z~3-6

We present an analysis of the star-formation rates (SFRs) and dust attenuation properties of star-forming galaxies at $2.7\leq z<6.5$ drawn from the Cosmic Evolution Early Release Science (CEERS) Survey. Our analysis is based on {\it JWST}/NIRSpec Micro-Shutter Assembly (MSA) $R\sim1000$ spectroscopic observations covering approximately $1-5$$\mu$m. Our primary rest-frame optical spectroscopic measurements are H$\alpha$/H$\beta$ Balmer decrements, which we use as an indicator of nebular dust attenuation. In turn, we use Balmer decrements to obtain dust-corrected H$\alpha$-based SFRs (i.e., SFR(H$\alpha$)). We construct the relationship between SFR(H$\alpha$) and stellar mass ($M_*$) in three bins of redshift ($2.7\leq z< 4.0$, $4.0\leq z< 5.0$, and $5.0\leq z<6.5$), which represents the first time the star-forming main sequence has been traced at these redshifts using direct spectroscopic measurements of Balmer emission as a proxy for SFR. In tracing the relationship between SFR(H$\alpha$) and $M_*$ back to such early times ($z>3$), it is essential to use a conversion factor between H$\alpha$ and SFR that accounts for the subsolar metallicity prevalent among distant galaxies. We also use measured Balmer decrements to investigate the relationship between dust attenuation and stellar mass out to $z\sim6$. The lack of significant redshift evolution in attenuation at fixed stellar mass, previously confirmed using Balmer decrements out to $z\sim2.3$, appears to hold out to $z\sim 6.5$. Given the rapidly evolving gas, dust, and metal content of star-forming galaxies at fixed mass, this lack of significant evolution in attenuation provides an ongoing challenge to explain.Comment: 9 pages, 4 figures, ApJ, in pres

Evaluation of farmer-grown improved sorghum cultivars for stover quality traits

Seeds of 4 improved high-yielding sorghum cultivars (CSH 16, CSV 15, PSV 16 and S 35) were supplied to 48 farmers from 4 villages (Manmarry, Udityal, Ganagpur and Kandawada) in the Mahabubnagar and Ranga Reddy districts of Andhra Pradesh, India. Each improved cultivar was planted along with the traditional yellow sorghum cultivar (locally called patcha jonna; intercropped with pigeon pea in a 5:1 row ratio) on black, barka (light black in colour with low fertility and low moisture retention capacity), chalka (red in colour with large pebbles and low fertility) and red soils. Data were recorded for stover nitrogen dry matter, crude protein and in vitro digestibility as well as grain and fodder yields. The results showed that the genetic component, rather than soil type and genotype x soil type interaction components, was important in total variation of the cultivars for stover nitrogen content and in vitro digestibility. The non-significant mean squares due to soil type and genotype x soil type interaction indicate the potential of genetic improvement of stover nitrogen content and in vitro digestibility for wide adaptation. Stover nitrogen dry matter was highest in CSH 16, followed by S 35, CSV 15 and PSV 16. The stover digestibility of improved cultivars was better than that of local sorghum. While the improved cultivars were on par with the local cultivars for stover nitrogen content irrespective of soil type, they were significantly superior to the local cultivar for stover digestibility in barka and red soils. The study provides sufficient evidence to dispel farmers' perceptions that improved cultivars have poor stover nutritive value and digestibility compared with local cultivars. Complementing the stover quality, the quantity obtained by the farmers with improved cultivars was better or comparable with local cultivars

Genomic Diversity at Thirteen Short Tandem Repeat Loci in a Substructured Caste Population, Golla, of Southern Andhra Pradesh, India

This is the publisher's version, also available electronically from http://digitalcommons.wayne.edu/humbiol/vol73/iss2/2/Genomic diversity based on 13 short tandem repeat (STR) loci was studied in seven population groups of a substructured Golla caste from Chittoor district in southern Andhra Pradesh, India. These groups are traditionally pastoral, culturally homogeneous, and strictly endogamous. Blood samples were drawn from 317 individuals from 30 Golla villages. The 13 STR loci analyzed in five standard multiplex polymerase chain reactions were: (1) CSF1R, TH01, and PLA2A; (2) F13A1, CYP19, and LPL; (3) D21S1446 and D21S1435; (4) D20S481, D20S473, and D20S604; and (5) D5S1453 and D6S1006. The average heterozygosity was found to be low among the Golla subgroups (0.64–0.70) in comparison to that of groups at the upper levels of the hierarchy. The coefficient of gene differentiation was found to be moderate (average GST = 0.031; range between 0.018 and 0.049 among the loci) when compared to that observed for a similar class of markers among populations with relatively higher levels of hierarchy, for example, among castes. It is, however, much higher when compared to the average observed for Indian caste and tribal populations, based on classical markers. Genetic distance measures revealed clusters of populations that are consistent with the known ethnohistorical and geographical backgrounds of the groups. We claim that these hypervariable markers are quite useful in understanding the process of substructuring within the Indian castes, leading to the formation of smaller breeding isolates, the basic Mendelian units within which microevolutionary forces operate

A Comparison of Deep Learning MOS Predictors for Speech Synthesis Quality

This paper introduces a comparison of deep learning-based techniques for the MOS prediction task of synthesised speech in the Interspeech VoiceMOS challenge. Using the data from the main track of the VoiceMOS challenge we explore both existing predictors and propose new ones. We evaluate two groups of models: NISQA-based models and techniques based on fine-tuning the self-supervised learning (SSL) model wav2vec2_base. Our findings show that a simplified version of NISQA with 40% fewer parameters achieves results close to the original NISQA architecture on both utterance-level and system-level performances. Pre-training NISQA with the NISQA corpus improves utterance-level performance but shows no benefit on the system-level performance. Also, the NISQA-based models perform close to LDNet and MOSANet, 2 out of 3 baselines of the challenge. Fine-tuning wav2vec2_base shows superior performance than the NISQA-based models. We explore the mismatch between natural and synthetic speech and discovered that the performance of the SSL model drops consistently when fine-tuned on natural speech samples. We show that adding CNN features with the SSL model does not improve the baseline performance. Finally, we show that the system type has an impact on the predictions of the non-SSL models.Comment: Submitted to INTERSPEECH 202

Decoupled sedimentary records of combustion : causes and implications

Author Posting. © American Geophysical Union, [year]. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 43 (2016): 5098–5108, doi:10.1002/2016GL069253.Pyrogenic carbon (PyC) is a collective term for carbon-rich residues comprised of a continuum of products arising from biomass burning and fossil-fuel combustion. PyC is ubiquitous in the environment where it can be transported by wind and water before being deposited in aquatic sediments. We compare results from four different methods used to trace PyC that were applied to a high-temporal resolution sedimentary record in order to constrain changes in PyC concentrations and fluxes over the past ~250 years. We find markedly discordant records for different PyC tracers, particularly during the preindustrial age, implying different origins and modes of supply of sedimentary PyC. In addition to providing new insights into the composition of sedimentary combustion products, this study reveals that elucidation of past combustion processes and development of accurate budgets of PyC production and deposition on local to regional scales requires careful consideration of both source characteristics and transport processes.UZH; NSF Grant Numbers: OCE-9708478, CHE-00891722016-11-3