13 research outputs found
Stress-induced ATP release from and growth modulation of human lens and retinal pigment epithelial cells
No full textATP release has been shown to occur following stimulation in several cellular systems. This study was undertaken to determine if lens and retinal epithelial cells release ATP in response to physiological stresses and to elucidate a possible role for ATP. Analysis of human aqueous humour samples showed a mean ATP level of 37.8+/-7.7 nM. Hyper-osmotic stress induced a dose- and time-dependent release of ATP. Both cell types were found to proliferate in serum-free medium, and the addition of ATP and adenosine at concentrations as low as 0.1 nM inhibited growth. Gene profiling also demonstrated the presence of the ectonucleotidases CD39 and CD73 and the A1 adenosine receptor on both cell types
TGFbeta isoform dependent Smad2/3 kinetics in human lens epithelial cells: A Cellomics analysis.
No full textInhibition of TGF beta 2 mediated effects on human lens epithelial cells by the human monoclonal antibody CAT-152.
No full textSynthesis of Macromolecules in Epithelial Cells of the Cultured Amphibian Lens: III. Involvement of Protein Synthesis in Mitotic Activation C)
No full textAnalysis of the Differential Expression Patterns of Sumoylation Enzymes E1, E2 and E3 in Ocular Cell Lines
No full textAnalysis of Non-Sumoylated and Sumoylated Isoforms of Pax-6, the Master Regulator for Eye and Brain Development in Ocular Cell Lines
No full textLocalization Patterns of Sumoylation Enzymes E1, E2 and E3 in Ocular Cell Lines Predict Their Functional Importance
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