“Suoni di seta: l’arte di Liu Fang”

Programma di sala per il concerto di Liu Fang 18 settembre 2007 h 17 e h 21, Torino, Teatro Baretti, Torino "Settembre Musica"

Additional file 2: of ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get Exercising): study protocol of a pragmatic, multicentre, randomised controlled trial testing physiotherapy for the prevention of complications and improved physical recovery after emergency abdominal surgery

EQ-5D-5L. EuroQual 5 Domains scoring. (DOCX 90 kb

Additional file 6: of ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get Exercising): study protocol of a pragmatic, multicentre, randomised controlled trial testing physiotherapy for the prevention of complications and improved physical recovery after emergency abdominal surgery

ICEAGE Data Dictionary. Data fields for ICEAGE. (DOCX 18 kb

Additional file 3: of ICEAGE (Incidence of Complications following Emergency Abdominal surgery: Get Exercising): study protocol of a pragmatic, multicentre, randomised controlled trial testing physiotherapy for the prevention of complications and improved physical recovery after emergency abdominal surgery

WHODAS. World Health Organisation disability assessment scale. (DOCX 20 kb

The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7

The canonical transient receptor potential channel subfamily (TRPC3, TRPC6, and TRPC7) contains Ca2+ permeable non-selective cation channels that are widely expressed in a variety of tissues. There is increasing evidence implicating TRPC channels, particularly TRPC3 and 6, in physiological and pathophysiological processes, eliciting interest in these channels as novel drug targets. Electrophysiology remains a benchmark technique for measuring ion channel function and accurately determining the pharmacological effects of compounds. In this report we describe the development of TRPC inhibitor assays on 2 automated planar patch clamp platforms - the IonWorks® Quattro™ and QPatch® systems. To enable activation of TRPC channels by carbachol, Chinese Hamster Ovary-K1 cells stably expressing the muscarinic M3 receptor were transduced with human TRPC3, TRPC6, or TRPC7 using BacMam viruses. TRPC3, 6, and 7 currents could be recorded on both platforms. However, the design of each platform limits which assay parameters can be recorded. Due to its continuous recording capabilities, the QPatch can capture both the activation and decay of the response. However, the transient nature of TRPC channels, the inability to reactivate and the large variation in peak currents limits the ability to develop assays for compound screening. The IonWorks Quattro, due to its discontinuous sampling, did not fully capture the peak of TRPC currents. However, due to the ability of the IonWorks Quattro to record from 64 cells per well, the variation from well to well was sufficiently reduced allowing for the development of medium-throughput screening assays. © Copyright 2014, Mary Ann Liebert, Inc. 2014

Baseline demographic and procedural characteristics for the PCI cohort.

<p>Baseline demographic and procedural characteristics for the PCI cohort.</p

Summary of adjusted outcomes comparing different DES types with CABG using different adjustment methods.

<p>Summary of adjusted outcomes comparing different DES types with CABG using different adjustment methods.</p

Summary of adjusted outcomes comparing PCI with CABG using different adjustment methods.

<p>Summary of adjusted outcomes comparing PCI with CABG using different adjustment methods.</p

Baseline demographic and procedural characteristics for total study population comparing CABG and PCI cohorts.

<p>Baseline demographic and procedural characteristics for total study population comparing CABG and PCI cohorts.</p

Baseline demographic and procedural characteristics for the CABG cohort.

<p>Baseline demographic and procedural characteristics for the CABG cohort.</p