Microwave imaging assisted ultrasonically

Disclosed is an apparatus and methodology for imaging objects, more particularly radiologically dense objects. The currently disclosed technology has particular applicability in the medical field as a tool and methodology for investigation of radiologically dense breast tissue of young patients by using microwave energy in concert with an ultrasonic initial investigation of the tissue. The use of an ultrasonic initial investigation operates as an initial evaluation point for the subsequent microwave investigation

The use of Mobile Applications in the Perioperative Management of Patients with Colorectal Cancer

Background and Aim: Colorectal cancer is the third most common cancer worldwide both in men and women. The scope of this systematic review was to investigate if mobile applications exists and what are the benefits in the screening, diagnostic, pre-operative preparation, or post-operative follow-ups on the patients with colorectal cancer.  Materials and Methods: We used the frame of PRISMA guideline. On September 1th, 2023, we systematically searched PubMed using the MeSH terms “Colorectal Neoplasms” and “Mobile Applications”. No restrictions on the types of articles or publication date were imposed. Results: A total of 24 items were retained. The article’s titles and abstracts were screened and 7 articles were removed due to the absence of the abstracts (n=2), the article described a prognostic scoring model (n=2), one was a systematic review, one was reviewing the use of SMS and one was a letter to the editor.  Out of the 17 remaining articles, only 7 were available in full text and all were testing mobile applications. The scope of using the applications was to facilitate screening (n=3), recovery (n = 3) and monitor chemotoxicity (n=1). Conclusions: Mobile tools appear as an opportunity for rapid access and increased adherence to colorectal cancer screening guidelines. Mobile applications focused on patient recovery post colorectal cancer surgery need a more patient-centric approach. The mobile application built for monitoring chemotoxicity was deemed to address many of the limitations of identifying and quantifying chemotherapy toxicities. All in all, mobile applications may enhance existing clinical care and provide cost‐effective real‐time patient support, which may reduce the likelihood of hospital admission

Large olfactory groove meningiomas: Clinical outcome considering different surgical approaches

Olfactory groove meningiomas (OGMs) account for 4.5 to 13% of all intracranial meningiomas (1,2). They arise in the anterior cranial fossa at the cribriform plate of the ethmoid bone and the area of the suture adjoining the planum sphenoidale.We performed a large retrospective study of 98 patients (59 females and 39 males) evaluated and operated in the Neurosurgical Department of the National Institute of Neurology and Neurovascular Diseases between 1979 – 2009. This represented 7.93% of all intracranial meningiomas operated in our department (1235 cases). These operations were done by or under the supervision of the senior neurosurgeon (LD). For the surgical removal of the OGMs we used both frontolateral (67 cases) or bifrontal approaches (31 cases). We achieved total removal of the meningioma in most of the cases (93.9%), meaning in 66 patients operated through unilateral frontolateral craniotomy (98.5%), and in 26 patients operated through bifrontal craniotomy (83.9%). As postoperative complications, were encountered: subdural hygroma, postoperative hemorrhage, cerebrospinal fluid (CSF) leak, postoperative seizures, diffuse cerebral edema and local infection. Postoperative mortality was 7.14% (7 patients). Frontolateral approach allowed, even in large OGMs, very good postoperative results, with high rates of total tumor resection and low rates of morbidity and mortality

High-Power, Computer-Controlled, Light-Emitting Diode–Based Light Sources for Fluorescence Imaging and Image-Guided Surgery

Optical imaging requires appropriate light sources. For image-guided surgery, in particular fluorescence-guided surgery, a high fluence rate, a long working distance, computer control, and precise control of wavelength are required. In this article, we describe the development of light-emitting diode (LED)-based light sources that meet these criteria. These light sources are enabled by a compact LED module that includes an integrated linear driver, heat dissipation technology, and real-time temperature monitoring. Measuring only 27 mm wide by 29 mm high and weighing only 14.7 g, each module provides up to 6,500 lx of white (400–650 nm) light and up to 157 mW of filtered fluorescence excitation light while maintaining an operating temperature ≤ 50°C. We also describe software that can be used to design multimodule light housings and an embedded processor that permits computer control and temperature monitoring. With these tools, we constructed a 76-module, sterilizable, three-wavelength surgical light source capable of providing up to 40,000 lx of white light, 4.0 mW/cm2 of 670 nm near-infrared (NIR) fluorescence excitation light, and 14.0 mW/cm2 of 760 nm NIR fluorescence excitation light over a 15 cm diameter field of view. Using this light source, we demonstrated NIR fluorescence–guided surgery in a large-animal model

Trends in Minimally Invasive Approaches for Liver Resections–A Systematic Review

Background: SILS (single incision laparoscopic surgery) and NOTES (natural orifice transluminal endoscopic surgery) are considered breakthroughs in minimally invasive surgery, the first consisting in the surgeon working via a single entrance site and the second via a natural orifice (e.g., oral cavity). Methods: Since 2000 until 2022, the original articles published in the online databases were analyzed. Eligible studies included information about the current therapy of patients with liver surgical pathology and how the two new techniques improve the surgical approach. Results: A total of 798 studies were identified. By applying the exclusion criteria, nine studies remained to be included in the review. Two out of nine studies examined the NOTES approach in liver surgery, whereas the other seven focused on the SILS technique. The age of the patients ranged between 24 and 83 years. Liver resections for hepatocellular carcinoma or colorectal metastases were undertaken and biliary or hydatid cysts were removed. The mean procedure time was 95 to 205 min and the average diameter of the lesions was 5 cm. Conclusions: When practiced by multidisciplinary teams, transvaginal liver resection is feasible and safe. The goals of SILS and NOTES are to be less intrusive, more easily tolerated and aesthetic

Determination of carbon nanotube density by gradient sedimentation

Density gradient centrifugation is a high-resolution technique for the separation and characterization of large molecules and stable complexes. We have analyzed various nanotube structures by preparative centrifugation in sodium metatungstate-water solutions. Bundled, isolated and acid-treated single-walled nanotubes (SWNTs) and multiwall nanotubes (MWNTs) formed sharp bands at well-defined densities. The structure of the material in each band was confirmed by transmission electron microscopy and Raman spectroscopy. Our data suggest respective densities of 1.87, 2.13, 1.74, and 2.1 g/cm(3) for bundled, isolated, and acid-treated SWNTs and MWNTs. These measured results compare well with their calculated densities