Eating disorders in weight-related therapy (EDIT): Protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management

The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that contribute to eating disorder risk. We present a protocol for a systematic review and individual participant data (IPD) meta-analysis which aims to identify participants at risk of developing eating disorders, or related symptoms, during or after weight management interventions conducted in adolescents or adults with overweight or obesity. We systematically searched four databases up to March 2022 and clinical trials registries to May 2022 to identify randomised controlled trials of weight management interventions conducted in adolescents or adults with overweight or obesity that measured eating disorder risk at pre- and post-intervention or follow-up. Authors from eligible trials have been invited to share their deidentified IPD. Two IPD meta-analyses will be conducted. The first IPD meta-analysis aims to examine participant level factors associated with a change in eating disorder scores during and following a weight management intervention. To do this we will examine baseline variables that predict change in eating disorder risk within intervention arms. The second IPD meta-analysis aims to assess whether there are participant level factors that predict whether participation in an intervention is more or less likely than no intervention to lead to a change in eating disorder risk. To do this, we will examine if there are differences in predictors of eating disorder risk between intervention and no-treatment control arms. The primary outcome will be a standardised mean difference in global eating disorder score from baseline to immediately post-intervention and at 6- and 12- months follow-up. Identifying participant level risk factors predicting eating disorder risk will inform screening and monitoring protocols to allow early identification and intervention for those at risk

Vertical Variation in Pollen Abundance in North-Central London

Pollen data from three samplers located at heights of 0.5m, 10m and 55 m were used to investigate vertical differences in pollen abundance in North-Central London. Weekly accumulative counts for all pollen types were collected from February to September 1988. Distinct variations in abundance between the sites were recorded for some pollen taxa. For example,Gramineae recorded greater abundance at the higher sampling position. Other pollen types, includingPlatanus, were recorded at consistently greater abundance at the 10 m height compared to the 55 m level. Significant differences between the pollen counts at these two heights are discussed in relation to pollen source area, the specific gravity of the pollen grain, airflow patterns of the urban area and the weather conditions affecting pollen dispersal. Tracer experiments using Lycopodium spores were employed to investigate dispersal patterns to all three sampling heights. The results from these trials are used to assist in the interpretation of data from the depositional samplers. The study reported in this paper forms part of a wider survey of 14 sampling sites examining spatial variations in pollen abundance