Automated 5-year Mortality Prediction using Deep Learning and Radiomics Features from Chest Computed Tomography

We propose new methods for the prediction of 5-year mortality in elderly individuals using chest computed tomography (CT). The methods consist of a classifier that performs this prediction using a set of features extracted from the CT image and segmentation maps of multiple anatomic structures. We explore two approaches: 1) a unified framework based on deep learning, where features and classifier are automatically learned in a single optimisation process; and 2) a multi-stage framework based on the design and selection/extraction of hand-crafted radiomics features, followed by the classifier learning process. Experimental results, based on a dataset of 48 annotated chest CTs, show that the deep learning model produces a mean 5-year mortality prediction accuracy of 68.5%, while radiomics produces a mean accuracy that varies between 56% to 66% (depending on the feature selection/extraction method and classifier). The successful development of the proposed models has the potential to make a profound impact in preventive and personalised healthcare.Comment: 9 page

Spectral Energy Distributions for Disk and Halo M--Dwarfs

We have obtained infrared (1 to 2.5 micron) spectroscopy for 42 halo and disk dwarfs with spectral type M1 to M6.5. These data are compared to synthetic spectra generated by the latest model atmospheres of Allard & Hauschildt. Photospheric parameters metallicity, effective temperature and radius are determined for the sample. We find good agreement between observation and theory except for known problems due to incomplete molecular data for metal hydrides and water. The metal-poor M subdwarfs are well matched by the models as oxide opacity sources are less important in this case. The derived effective temperatures for the sample range from 3600K to 2600K; at these temperatures grain formation and extinction are not significant in the photosphere. The derived metallicities range from solar to one-tenth solar. The radii and effective temperatures derived agree well with recent models of low mass stars.Comment: 24 pages including 13 figures, 4 Tables; accepted by Ap

FeH Absorption in the Near-Infrared Spectra of Late M and L Dwarfs

We present medium-resolution z-, J-, and H-band spectra of four late-type dwarfs with spectral types ranging from M8 to L7.5. In an attempt to determine the origin of numerous weak absorption features throughout their near-infrared spectra, and motivated by the recent tentative identification of the E 4\Pi- A ^4\Pi system of FeH near 1.6 microns in umbral and cool star spectra, we have compared the dwarf spectra to a laboratory FeH emission spectrum. We have identified nearly 100 FeH absorption features in the z-, J-, and H-band spectra of the dwarfs. In particular, we have identified 34 features which dominate the appearance of the H-band spectra of the dwarfs and which appear in the laboratory FeH spectrum. Finally, all of the features are either weaker or absent in the spectrum of the L7.5 dwarf which is consistent with the weakening of the known FeH bandheads in the spectra of the latest L dwarfs.Comment: accepted by Ap