COVID-19 and Guillain-Barre Syndrome: a systematic review of case reports

Background: Guillain-Barre Syndrome (GBS) is a neurological autoimmune disease that can lead to respiratory failure and death. Whether COVID-19 patients are at high risk of GBS is unknown. Through a systematic review of case reports, we aimed to summarize the main features of patients with GBS and COVID-19. Methods: Without any restrictions, we searched MEDLINE, Embase, Global Health, Scopus, Web of Science and MedXriv (April 23 rd , 2020). Two reviewers screened and studied titles, abstracts and reports. We extracted information to characterize sociodemographic variables, clinical presentation, laboratory results, treatments and outcomes. Results: Eight reports (n=12 patients) of GBS and COVID-19 were identified; one was a Miller Fisher case. Overall, the median age was 62.5 (interquartile range (IQR)=54.5-70.5) years, and there were more men (9/102). GBS symptoms started between 5 and 24 days after those of COVID-19. The median protein levels in cerebrospinal fluid samples was 101.5 mg/dl (IQR=51-145). None of the cerebrospinal fluid samples tested positive for COVID-19. Six patients debuted with ascendant weakness and three with facial weakness. Five patients had favourable evolution, four remained with relevant symptoms or required critical care and one died; the Miller Fisher case had successful resolution. Conclusions: GBS is emerging as a disease that may appear in COVID-19 patients. Although limited, preliminary evidence appears to suggest that GBS occurs after COVID-19 onset. Practitioners and investigators should have GBS in mind as they look after COVID-19 patients and conduct research on novel aspects of COVID-19. Comparison with GBS patients in the context of another viral outbreak (Zika), revealed similarities and differences that deserves further scrutiny and epidemiological studies

Estimativa da capacidade de suporte das pastagens nativas do Pantanal, sub-região da Nhecolândia.

Este estudo teve como finalidade avaliar as variações mensais da capacidade de suporte de uma área no Pantanal, e propor um cálculo geral de estimativa da capacidade de suporte para as pastagens nativas, com base na produtividade e seletividade das forrageiras existentes nas unidades de paisagem preferidas por bovinos na subregião da Nhecolândia, Pantanal. O estudo foi efetuado numa área de 151 ha, com rebanho de 46 vacas de cria, no período de outubro de 1997 a setembro de 1999. Foram avaliados mensalmente a produção de matéria seca total nas unidades de campo limpo e baixadas, e as respectivas produções de matéria seca total e selecionada dos principais sítios utilizados para pastejo. Um algoritmo foi aplicado para a obtenção das estimativas da capacidade de suporte que foram variáveis entre meses, especialmente no ano hidrológico de 1998/99, considerado "atípico" em relação à distribuição de chuvas. Portanto, a capacidade de suporte de uma invernada não deve seguir regras fixas, e sim flexíveis, de acordo com a proporção de ambientes e condições climáticas de cada propriedade. No entanto, em termos práticos foi proposto cálculo geral anual, que pareceu ser adequado para os anos que apresentam distribuição regular das chuvas.bitstream/item/37425/1/BP27.pd

Seismotectonics of the Southern Apennines and Adriatic foreland: insights on active regional E-W shear zones from analogue modeling

The active tectonics at the front of the Southern Apennines and in the Adriatic foreland is characterized by E-W striking, right-lateral seismogenic faults, interpreted as reactivated inherited discontinuities. The best studied among these is the Molise-Gondola shear zone (MGsz). The interaction of these shear zones with the Apennines chain is not yet clear. To address this open question we developed a set of scaled analogue experiments, aimed at analyzing: 1) how dextral strike-slip motion along a pre-existing zone of weakness within the foreland propagates toward the surface and affects the orogenic wedge; 2) the propagation of deformation as a function of displacement; 3) any insights on the active tectonics of Southern Italy. Our results stress the primary role played by these inherited structures when reactivated, and confirm that regional E-W dextral shear zones are a plausible way of explaining the seismotectonic setting of the external areas of the Southern Apennines

Modes of fault reactivation from analogue modeling experiments: implications for the seismotectonics of the southern Adriatic foreland (Italy)

The active tectonics at the front of the Southern Apennines and in the Adriatic foreland is characterized by E-W striking, right-lateral seismogenic faults, interpreted as reactivated inherited discontinuities. The best studied among these is the Molise-Gondola shear zone (MGsz). The interaction of these shear zones with the Apennines chain is not yet clear. To address this open question we developed a set of scaled analogue experiments, aimed at analyzing: 1) how dextral strike-slip motion along a pre-existing zone of weakness within the foreland propagates toward the surface and affects the orogenic wedge; 2) the propagation of deformation as a function of increasing displacement; 3) any insights on the active tectonics of Southern Italy. Our results stress the primary role played by these inherited structures when reactivated, and confirm that regional EW dextral shear zones are a plausible way of explaining the seismotectonic setting of the external areas of the Southern Apennines

Avaliação da prevenção e controle da anemia infecciosa equina no Pantanal.

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Uréia sérica, escore corporal e peso de fêmeas bovinas mantidas em pastagem nativa, Pantanal Mato-Grossense-do-Sul.

Neste trabalho objetivou-se avaliar as variações nos níveis de uréia sérica e suas relações com o peso e escore corporal de animais pertencentes a um rebanho de cria, nos períodos seco e chuvoso, na sub-região da Nhecolândia, Pantanal de Mato Grosso do Sul.bitstream/item/80587/1/CT95.pd

Emergency-department accesses in home care paediatric patients: Occurrence and risks of use in a six-year retrospective investigation in Northern Italy

Objective To assess the determinants of ED use in paediatric patients enrolled in an Integrated Paediatric Home Care (IPHC) program. Methods A retrospective study was conducted using administrative databases on a cohort of patients enrolled in an IPHC program between January 1st, 2012, and December 31st, 2017, in Northern Italy. ED visits that occurred during the IPHC program were considered. Data were collected considering sociodemographic, clinical and organizational variables. A multivariable stepwise logistic regression analysis was performed. The dependent variable to identify possible associations was ED visit. Results A total of 463 ED visits occurred in 465 children, with an incidence rate of 1. The risk of ED visits significantly increased among children involved in the IPHC program after hospital discharge (OR 1.94). Additionally, the risk of ED visits increased significantly as the duration of IPHC increased (OR 5.80 between 101 and 200 days, to OR 7.84 between 201 and 300 days, OR 12.54 between 301 and 400 days and OR 18.67 to more than 400 days). Conclusion The overall results represent a practical perspective to contribute improving both the service quality of IPHC and reducing low acuity and improper ED use

Mapeamento de unidades de paisagem em nível de fazenda, Pantanal da Nhecolândia.

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Classificação preliminar das paisagens da sub-região do Abobral, Pantanal, usando imagens de satélite.

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Unidades demonstrativas de plantas medicinais, aromáticas e condimentares da Embrapa Pantanal, em Corumbá, MS.

A implantação de Unidades Demonstrativas de plantas medicinais, aromáticas e condimentares da Embrapa Pantanal, em parceria com a Associação de Pais e Mestres dos Excepcionais (APAE) e com a Empresa Brasileira de Infra-estrutura Aeroportuária (Infraero), em Corumbá, é uma das ações do projeto “Plantas condimentares: uma opção para agregação de valor e renda à agricultura familiar”, desenvolvido pelo Escritório de Negócios de Campinas, em parceria com centros de pesquisa da empresa, além de universidades, produtores e empresas privadas de várias regiões do país. O objetivo deste trabalho é identificar locais e genótipos de qualidade e adequados à produção de plantas medicinais, condimentares e aromáticas, além de aprimorar a qualificação de técnicos e a implantação de unidades de observação, demonstração, produção e processamento destas plantas, criando novas alternativas de renda para pequenos e médios agricultores.Disponível também em: Cadernos de Agroecologia, V. 5, n.1, 2010