MarkLogic Database – Only Enterprise NoSQL DB

MarkLogic DB is one of the Enterprise NoSQL database that supports multiple-model database design. It is optimized for structured and unstructured data that allows to store, manage, query and search across JSON, XML, RDF (Triplestore) and can handle data with a schema free and leads to faster time-to-results by providing handling of different types of data. It provides ACID Transactions using MVCC (multi-version concurrency control). One of the important key feature of MarkLogic is its Bitemporal behavior by providing data at every point in time. Due to its shared-nothing architecture it is highly available and easily and massively scalable with no single point of failure making structured data integration easier. It also has incremental backup means to only backup the updated data. Marklogic provides Hadoop integration and Hadoop is designed to store large amount of data in Hadoop Distributed File System (HDFS) and works better with the transactional applications

Effects of Hematocrit on Impedance and Shear Stress during Stenosed Artery Catheterization

The flow of blood through a stenosed catheterized artery has been studied. To observe the effects of hematocrit, blood has been represented by a two-phase macroscopic model (i.e., a suspension of red cells in plasma). It is found that for any given catheter size, the impedance increases with hematocrit and also for a given hematocrit, the same increases with the catheter size. In the stenotic region, the wall shear stress increases in the upstream of the stenosis throat and decreases in the downstream in an uncatheterized artery but the same possesses an opposite character in the case of a catheterized artery. The shear stress at the stenosis throat possesses the character similar to the flow resistance (impedance) with respect to the hematocrit for a given catheter size, however, the same decreases with an increase in the size of the catheter for any given hematocrit

Birefringence analysis of multilayer leaky cladding optical fibre

We analyse a multilayer leaky cladding (MLC) fibre using the finite element method and study the effect of the MLC on the bending loss and birefringence of two types of structures: (i) a circular core large-mode-area structure and (ii) an elliptical-small-core structure. In a large-mode-area structure, we verify that the multilayer leaky cladding strongly discriminates against higher order modes to achieve single-mode operation, the fibre shows negligible birefringence, and the bending loss of the fibre is low for bending radii larger than 10 cm. In the elliptical-small-core structure we show that the MLC reduces the birefringence of the fibre. This prevents the structure from becoming birefringent in case of any departures from circular geometry. The study should be useful in the designs of MLC fibres for various applications including high power amplifiers, gain flattening of fibre amplifiers and dispersion compensation.Comment: 18 page

Variant origin of superior polar artery and unusual hilar branching pattern of renal artery with clinical correlation

Classically, a single renal artery arising from the abdominal aorta supplies the respective kidney on each side. Near the hilum of the kidney each renal artery divides into anterior and posterior branchs, which in turn divide into segmental arteries supplying the different renal segments. A total of 84 formalin fixed cadavers (73 male and 11 female, 168 kidneys in total) constituted the material for the study. During routine abdominal dissection conducted for medical undergraduates, the kidneys and their arteries were explored and variations in morphological patterns of renal arteries were noted. We observed superior polar renal artery in 22.6% cases. Superior polar renal arteries had different sources of origin. In 10.7% of cases it came directly from the abdominal aorta as an accessory renal artery; in 5.4% of cases as a direct branch from the main renal artery; in 3.6% of cases from the superior hilar renal artery (from one of the duplicated renal arteries); and in 3.0% of cases from a segmental branch of the renal artery. We also observed unusual hilar branching patterns of renal arteries, which included a fork pattern in 11.3% of cases, ladder pattern in 7.7% of cases, net pattern in 5.9% of cases, and triplicate in 3.0% of cases. Understanding the anatomy of vascular variations of the kidney is essential for the clinician to be able to perform procedures such as renal transplantation, interventional radiological procedures, and renal vascular operations more safely and efficiently. (Folia Morphol 2011; 70, 1: 24-28

Variations in the formation of the median nerve and its clinical correlation

Variations in the formation of the median nerve are of interest to anatomists, radiologists, and surgeons. These variations may be vulnerable to damage in surgical operations, but their knowledge also helps in the interpretation of a nervous compression having unexplained clinical symptoms. We studied the variation in the formation of the median nerve in 87 cadavers, i.e. 174 upper limbs of formalin preserved cadavers at the department of Anatomy, Subharti medical college. We observed an additional root taking part in the formation of the median nerve in 26.4% of upper limbs, unusual low formation of the median nerve in the arm in front of the brachial artery in 18.4% of upper limbs, and median nerve formation medial to the axillary artery in 10.3% of upper limbs. Knowledge of such anatomical variations is of interest to the anatomist and clinician alike. Surgeons who perform procedures involving neoplasm or trauma repair need to be aware of these variations

Pattern of antidepressant prescription at tertiary (mental hospital vs medical college) care centre of central India

Background: Western literature full of extensively study the antidepressant prescription pattern at different settings. Recently in Indian context multicentre study and individual centers reported pattern of antidepressant uses for management of depression. With the time newer antidepressant approved, with better understanding of evidence based pathogenesis of illness influence the treatment patterns. Mental hospital setting is different that medical college setting at least for stigma related issue. The aim of the research work was to study the pattern of antidepressant prescription at mental hospital and medical college settings.Methods: Cross-sectional assessments were done at mental hospital and medical college centers. Subjects diagnosed as depressive episode as per ICD 10, age >18 year included in study. Total 105 treatment seeking subject included in study from both centers Data was collected on socio-demographic characteristics, Clinical profile and prescribed medication.Results: 49 subjects from mental hospital, 56 subjects from medical college included in study. Mean age of study sample 39.27±12.96 vs 37.49±14.90 years respectively at mental hospital and medical college centers. Escitalopram prescribed 83.7% subjects, 53.3 % subjects receive monotherapy. L methyl folate and atypical antipsychotics was most commonly adjunctive medication with antidepressants.Conclusions: In sociodemographic differences subjects attending mental hospital belong to lower socioeconomic status compare to subject attending mental hospitals. There were no significant differences in prescription pattern of antidepressant medication for treatment of depressive episode. Escitalopram most commonly prescribed antidepressant and L methyl folate and atypical antipsychotics was most commonly used adjuvant with antidepressant medications.

A comparative study of inflammatory marker highly sensitive C- Reactive Protein in depression patients exhibiting suicidal behaviour and depression patients without suicidal behaviour

Background: Recent research have found a link between inflammatory pathway and suicidal behaviour. hs-CRP, IL, TNF have been shown to have significant alterations in suicidality, however multiple covariates influence this relationship. One of the main limitations of most of the studies is that they have evaluated the CRP in patients demonstrating suicidal behaviour but not in depression. No study has been conducted in Indian subpopulation with parameters of our study. Aims of the study was to compare hsCRP levels between depression patients with suicidal behaviour and without suicidal behaviour.Methods: Authors compared 50 depression patients with suicidal behaviour and 50 depression patients without suicidal behaviour, diagnosed using ICD10. Hamilton Depression Rating Scale (HDRS‑17), Suicide behaviour Questionnaire- Revised (SBQ-R), Beck Scale for Suicidal Ideation (BSSI) were applied for assessment of depression and suicidality. Highly sensitive CRP was measured using autoanalyzer.Results: hsCRP levels were significantly high in depression patients with suicidal behaviour (4.12 mg/dl) than depression without suicidal behaviour (2.42 mg/dl). Duration of illness, HAM-D, BSSI and SBQ-R scores correlated positively with hsCRP levels.Conclusions: Depression with suicidal behaviour patients have a significantly higher hs-CRP levels than depression without suicidal behaviour. Patients of depression with suicidal behaviour group have a strong positive correlation between hs-CRP levels and HAM-D, BSSI and SBQ-R scores

Co-axial dual-core resonant leaky fibre for optical amplifiers

We present a co-axial dual-core resonant leaky optical fibre design, in which the outer core is made highly leaky. A suitable choice of parameters can enable us to resonantly couple power from the inner core to the outer core. In a large-core fibre, such a resonant coupling can considerably increase the differential leakage loss between the fundamental and the higher order modes and can result in effective single-mode operation. In a small-core single-mode fibre, such a coupling can lead to sharp increase in the wavelength dependent leakage loss near the resonant wavelength and can be utilized for the suppression of amplified spontaneous emission and thereby gain equalization of an optical amplifier. We study the propagation characteristics of the fibre using the transfer matrix method and present an example of each, the large-mode-area design for high power amplifiers and the wavelength tunable leakage loss design for inherent gain equalization of optical amplifiers.Comment: 6 page