Orange-Brown Precipitate: A Threat to the Success of Endodontic Treatment – An In Vitro Study

AIM: The aim of the present study was to evaluate the effect of various intermediate irrigating solutions in the removal of orange-brown precipitate formed due to alternative use of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) root canal irrigants. METHODS: The root canals of 50 mandibular premolars were prepared using ProTaper Universal Rotary instruments (Dentsply Maillefer, Ballaigues, Switzerland) up to size F3. The roots were randomly divided into five experimental groups specified by the intermediate irrigant used; Group 1: No intermediate irrigant used (control), Group 2: Saline, Group 3: 7% maleic acid (MA), Group 4: 4% sodium thiosulfate, and Group 5: 70% isopropyl alcohol (n = 10). After final irrigation with CHX, the specimens were evaluated for the presence/absence of orange-brown precipitate under stereomicroscope. RESULTS: Mean precipitate for all experimental groups was calculated using ANOVA F test which showed orange-brown precipitate (parachloroanaline) in all groups except Group 4 and Group 5 which were highly significant (p < 0.001) at all the levels of root canal. Intergroup pairwise comparison was done using Tukey’s post hoc test. CONCLUSION: About 7% MA is effective in minimizing the formation of orange-brown precipitate when used as intermediate irrigant between NaOCl and CHX. However, the precipitate was not observed with 4% sodium thiosulfate and 70% isopropyl alcohol

A CONTROLLED CLINICAL STUDY ON THE EFFECT OF CERTAIN INDIGENOUS DRUGS IN SHAKHASHRITA KAMALA WITH SPECIAL REFERENCE TO VIRAL HEPATITIS-B

Hepatitis-B is an infective disease predominantly affecting liver. Along with AIDS, which has been a major concern since 90s. Many of the Ayurvedic herbal medicines have been tried and have been proved to be effective in treating Shakhashrita kamala. The objective of the study was to see the effect of tablet Nirocil and indigenous drugs Kashaya in Shakhashrita kamala (Hepatitis-B) and to compare both of them. A Total of 26 patients, after considering the inclusion and exclusion criteria, having signs and symptoms of Shakhashrita kamala were included in the study and after diagnosing Hepatitis-B by elevated liver function tests and HBsAg (Elisa). Patients were assessed and scores were given with regards to the subjective parameters like Peetata of netra, Peetata of Mootra, Peetata of Jihwa jala, Swethavarchas, Kandu and objective parameters like total bilirubin, and HBsAg. All the subjective parameters are recorded and assessed on initial day, during and after treatment. Objective parameters are assessed before and after treatment. Out of 26 patients, 10 patients got completely cured, 8 patients got improvement and 8 patients got slight improvement. Overall assessment of the study revealed that, after treatment of 26 patients, there were 8 patients having HBsAg positive result and 18 patients were having HBsAg negative result which was highly significant. Both the groups showed significant positive in subjective parameters. Thus study revealed that indigenous drugs Kashaya has significant role to play in the management of Shaksahashrita kamala. To conclude, the study emphasized that indigenous drugs Kashaya has significant role to play in the management of Shaksahashrita kamala