Alcohol use and alcohol-use disorders among older adults in India: a literature review.

OBJECTIVES: With changing attitudes to alcohol and an increasing life span in India, the prevalence of alcohol use and misuse in successive cohorts of older people is likely to increase. In this paper, we attempt to review the most recent evidence covering alcohol use and alcohol-use disorders in the Indian elderly. METHODS: PubMed, PsycINFO and Indmed databases were searched using relevant keywords. Papers meeting eligibility criteria were selected through a sequential process of screening title, abstract and full text. Data were extracted into Excel sheets. RESULTS: There was a dearth of pan-national studies. There were several methodological issues with many studies especially related to measurement. A substantial proportion of individuals above the age of 50 years are current consumers of alcohol and the prevalence is generally higher in urban compared to rural areas. Older women are generally likely to be alcohol abstainers. The general trend appears to be a reduction in current drinking among successive age cohorts over the age of 50. Alcohol consumption in the older adults is associated with educational status, health status, chronic morbidity, employment status, socioeconomic status, auditory/locomotor impairment and asthma. CONCLUSION: Alcohol use and misuse is a problem among the Indian older adults. With socio-demographic changes that will further increase longevity, this problem is likely to increase and policy-makers need to plan for it. Future research needs to improve validity and reliability in study methodology, as well as add to the current evidence base

A Lower Bound for Radio kk-chromatic Number of an Arbitrary Graph

Radio $k$-coloring is a variation of Hale's channel assignment problem, in which one seeks to assign positive integers to the vertices of a graph $G$, subject to certain constraints involving the distance between the vertices. Specifically, for any simple connected graph $G$ with diameter $d$ and apositive integer $k$, $1\leq k \leq d$, a radio $k$-coloring of $G$ is an assignment $f$ of positive integers to the vertices of $G$ such that $|f(u)-f(v)|\geq 1+k-d(u, v)$, where $u$ and $v$ are any two distinct vertices of $G$ and $d(u, v)$ is the distance between $u$ and $v$.In this paper we give a lower bound for the radio $k$-chromatic number of an arbitrarygraph in terms of $k$, the total number of vertices $n$ and apositive integer $M$ such that $d(u,v)+d(v,w)+d(u,w)\leq M$ for all $u,v,w\in V(G)$. If $M$ is the triameter we get a better lower bound. We also find the triameter $M$ for several graphs, and show that the lower bound obtained for these graphs is sharp for the case $k=d$

Organic carbon in sediments of the Southwestern margin of India: influence of productivity and monsoon variability during the late Quaternary

The texture, organic carbon (OC), CaC03 and Rock-Eval parameters of the sediments from two gravity cores collected at depths below the oxygen minimum zone (OMZ) of the southwestern margin of India are presented and compared the results with those within the OMZ. Clayey silt/ silty clays are the characteristic sediments. The OC in the core top sediments between Cape Comorin and Mangalore is higher below the OMZ than those from the OMZ. However, it is higher within the OMZ than those below the OMZ in the sediments between Mangalore and Goa. The down-core variations of OC are identical in these cores. In both the cores, relatively high OC content and low sedimentation rates correspond to the intervals of late Holocene and Last Glacial Maximum (LGM) and, low OC and high sedimentation rates to the early Holocene sediments. The CaC03 follows sand content in a core off Cape Comorin, with low values at the core top, increase marginally in the early Holocene and LGM and then decrease in the late Pleistocene sediments. The CaC03 values in a core off Mangalore are higher in the intervals of the late Holocene and early deglaciation than m early Holocene and LGM intervals. Rock-Eval parameters distinguish the sources of organic matter only at high OC concentrations. The high OC during the LGM may be related to the productivity, associated with convective mixing occurring during the NE monsoon. The low OC/CaC03 and high clay content during the early Holocene may be the consequences of the intensified SW monsoon that results in stronger near-surface stratification leading to low productivity High OC and low CaC03 during the late Holocene suggest increased productivity and early diagenesis in the near surface sediments. We suggest that the variations in productivity and downslope transport of sediment controlled the OC enrichment

Paleoclimatic and diagenetic history of the Late Quaternary sediments in a core from the Southeastern Arabian Sea: geochemical and magnetic signals

Geochemical and rock-magnetic investigations were carried out on a sediment core collected from the SE Arabian Sea at 1420 m depth in oxygenated waters below the present-day oxygen minimum zone. The top 250 cm of the core sediments represent the last 35 kaBP. The δ18O values of Globigerinoides ruber are heaviest during the Last Glacial Maximum (LGM) and appear unaffected by low-saline waters transported from the Bay of Bengal by the strong northeast monsoon and West Indian coastal current. The signatures of Bølling-Allerød and Younger Dryas events are distinct in the records of magnetic susceptibility, organic carbon (OC) and δ 18O. Glacial sediments show higher OC, CaCO3, Ba, Mo, U and Cd, while the early-to-late Holocene sediments show increasing concentrations of OC, CaCO3, Ba, Cu, Ni and Zn and decreasing concentrations of Mo, U and Cd. Productivity induced low-oxygenated bottom waters and reducing sedimentary conditions during glaciation, and productivity and oxygenated bottom waters in the Holocene are responsible for their variation. The core exhibits different stages of diagenesis at different sediment intervals. The occurrence of fine-grained, low-coercivity, ferrimagnetic mineral during glacial periods is indicative of its formation in organic-rich, anoxic sediments, which may be analogous to the diagenetic magnetic enhancement known in sapropels of the Mediterranean Sea and Japan Sea. The glacial sediments exhibiting reductive diagenesis with anoxic sedimentary environment in this core correspond to reductive diagenesis and intermittent bioturbation (oxygenation) reported in another core in the vicinity. This suggests that the poorly oxygenated bottom water conditions during glacial times should not be generalized, but are influenced locally by productivity, sedimentation rates and sediment reworking

Wind-driven estuarine turbidity maxima in Mandovi Estuary, central West coast of India

Systematic studies on the suspended particulate matter (SPM) measured on a seasonal cycle in the Mandovi Estuary, Goa indicate that the average concentrations of SPM at the regular station are ~20mg/l, 5mg/l, 19mg/l and 5mg/l for June–September, October–January, February–April and May, respectively. SPM exhibits low-to-moderate correlation with rainfall indicating that SPM is also influenced by other processes. Transect stations reveal that the SPM at sea-end stations of the estuary are at least two orders of magnitude greater than those at the river-end during the monsoon. Estuarine turbidity maximum (ETM) of nearly similar magnitude occurs at the same location in two periods, interrupted by a period with very low SPM concentrations. The ETM occurring in June–September is associated with low salinities; its formation is attributed to the interactions between strong southwesterly winds (5.1–5.6ms-1) and wind-induced waves and tidal currents and, dominant easterly river flow at the mouth of the estuary. The ETM occurring in February–April is associated with high salinity and is conspicuous. The strong NW and SW winds (3.2–3.7ms-1) and wind-driven waves and currents seem to have acted effectively at the mouth of the estuary in developing turbidity maximum. The impact of sea breeze appears nearly same as that of trade winds and cannot be underestimated in sediment resuspension and deposition

Rock magnetic and geochemical record in a sediment core from the Eastern Arabian Sea: diagenetic and environmental implications during the late Quaternary

Rock magnetic concentration, grain size and mineralogy parameters together with organic carbon, calcium carbonate, redox-sensitive elements, δ18O of Globigerinoides ruber and radiocarbon dating were carried out on a 445 cm long sediment core collected at 1380 m depth off Mangalore, southwestern margin of India. The top 290 cm sediments of the core correspond to the last 18 kaBP. The δ18O and magnetic records exhibit major events at ∼ 16 kaBP, 14.5 kaBP, 11.5 kaBP and 9.8/8.6 kaBP related to start and intensity of the summer monsoon and climate change, and are synchronous with that of the western Arabian Sea and North Atlantic. The sediments with high magnetic susceptibility correlate with high sedimentation rates. The sediments are dominated by fine-grained magnetite, but intervals of 1.2-3.8 kaBP and 10-13.5 kaBP were subjected to diagenetic changes, resulting in the dissolution of fine-grained magnetites and enrichment of redox-sensitive trace elements (Cu, Ni, Zn, V, Mo and U). The sediments between 290 cm and 445 cm correspond to 18-27 kaBP and are characterized by distinct decrease in magnetic concentration, grain size and mineralogy parameters, high organic carbon, low concentrations of redox-sensitive trace elements and abundant pyritized tubules. The reductive diagenetic conditions indicated by rock magnetic properties are in contrast with the weak sub-oxic conditions revealed by low concentrations of trace elements in the sediments. The seasonal organic matter flux produced during the winter monsoon and moderate sedimentation rates favoured reductive diagenesis in the sediments at and below the last glacial maximum (LGM). Intermittent bioturbation, however, allowed oxidants to penetrate into the sediments, remobilized redox-sensitive trace elements into the water column and modified the primary geochemical signal of the sedimentary environment

The nature and distribution of particulate matter in the Mandovi estuary, Central West coast of India

Systematic seasonal variations of suspended particulate matter (SPM) along a 44-km transect of the Mandovi estuary reveal that the concentrations of SPM are low at river-end stations, increase generally seaward, and are highest at sea-end stations of the estuary. An estuarine turbidity maximum (ETM) occurs at sea-end stations during June-September when river discharge is high and also in February-May when river discharge is low. These are the two windiest times of year, the former associated with the southwest monsoon and the latter characterized by a persistent sea breeze. The salinity vs. SPM plot shows that high SPM is a seaward deposit and skewed landward. Suspended matter comprised of floccules, fecal pellets, and aggregates that consist of clay and biogenic particles occur everywhere in the estuary. Diatoms are the most common and are of marine type at the sea-end and freshwater-dominated at river-end stations of the estuary. SPM is characterized by kaolinite- and smectite-rich clay mineral suites at the river- and sea-end stations, respectively. Smectite concentrations increase seawards with the increase in SPM content and are not influenced by salinity. Wind-driven waves and currents and biogeochemical processes at the mouth of estuary likely play an important role in the formation of ETM in resuspension and transformation of SPM into floccules and aggregates and in their upkeep or removal

Origin of Cretaceous phosphorites from the onshore of Tamil Nadu, India

Cretaceous phosphorites from the onshore of Tamil Nadu have been investigated for their origin and compared with those in the offshore. Cretaceous phosphorites occur as light brown to yellowish brown or white nodules in Karai Shale of the Uttatur Group in the onshore Cauvery basin. Nodules exhibit phosphatic nucleus encrusted by a chalky shell of carbonate. The nucleus of the nodules consists of light and dark coloured laminae, phosphate peloids/coated grains and detrital particles interspersed between the laminae. Scanning electron microscope (SEM) studies reveal trapping and binding activity of microbial filaments. A mat structure with linearly arranged microbial filaments and hollow, cell-based coccoid cyanobacterial mat are present. Nodules contain abundant carbonate fluorapatite, followed by minor calcite, quartz and feldspar. The P2O5 content of the phosphorites ranges from 18 to 26%. The CaO/P2O5, Sr and F contents are higher than that of pure carbonate fluorapatite. Concentrations of Si, Al, K, Fe, and Ti are low. We suggest that the nuclei of the nodules represent phosphate clasts related to phosphate stromatolites formed at intertidal conditions. At high energy levels the microbial mats were disintegrated into phosphate clasts, coated with carbonate and then reworked into Karai Shale. On the other hand, Quaternary phosphorites occur as irregular to rounded, grey coloured phosphate clasts at water depths between 180 and 320m on the continental shelf of Tamil Nadu. They exhibit grain-supported texture. Despite Quaternary in age, they also resemble phosphate stromatolites of intertidal origin and reworked as phosphate clasts onto the shelf margin depressions. Benthic microbial mats probably supplied high phosphorus to the sediments. Availability of excess phosphorus seems to be a pre-requisite for the formation of phosphate stromatolites

Fluctuations in productivity and denitrification in the Southeastern Arabian Sea during the Late Quaternary

Sedimentological and stable isotopic characteristics of sediments have been studied in a core from the southeastern Arabian Sea containing records of the past 70 ka. Palaeoproductivity proxies such as organic carbon (Corg), total nitrogen (TN) and calcium carbonate (CaCO3) contents, show high values at the core top and during the Last Glacial Maximum (LGM) and marine isotope stage (MIS) 4, suggesting high productivity, whereas low Corg and CaCO3 contents are associated with the MIS ½ and mid-MIS 3, indicating reduced productivity. The δ18O values in planktonic foraminifera range between - 2.7% and - 0.1%, with a large glacial-interglacial amplitude Δδ18O of ∼2.6%, suggesting changes related to monsoonal precipitation/ runoff. The δ15N values fluctuate between 5.4% and 7.3%, signifying variation in denitrification intensity. The δ15N indicates an overall increase in denitrification intensity during MIS 1 and MIS 3 and, reduced intensity during MIS ½, LGM and mid-MIS 3. Higher primary productivity and reduced denitrification intensity during LGM and MIS 4 might be due to convective winter mixing and more oxygenated subsurface waters. Reduced primary productivity during MIS ½ and mid-MIS 3 might be the effect of enhanced precipitation associated with the intensified southwest monsoon fortifying near-surface stratification

Concept of Diabetic Neuropathy and its management in Ayurveda

Diabetes mellitus is a giant disease considered as one of the arch enemies of the mankind. The evidences at present suggest that incidence of Diabetes mellitus is raising among the general population. In Ayurveda, Diabetes mellitus closely resembles a disorder called Madhumeha, which is a subtype of Vataja Prameha. In Avarnjanya Madhumeha vitiated Kapha, Pitta and Meda causes Avarana to Vata that leads its aggravation causing diminution of vital Dhatus. This may lead to the complication of Madhumeha such as Diabetic Neuropathy. According to Ayurvedic principles there is involvement of Vata and Pitta Dosha in diabetic neuropathy. The drugs used conventionally are mostly for relief in the symptoms and moreover they have certain side effects. Many single drugs and Ayurvedic formulations are used in practice have significant effect on the symptoms of numbness, tingling, burning sensation and pain in the patients of diabetic neuropathy