Development of a creep data base management system for engineering materials

A fully menu driven creep data base management system has been developed for various high temperature materials using the client /server (C/S) architecture with Sybase system. 10 as backend and power builder 4.0 as an inter-face. The relational data base constitutes of various classes of materials, their heat treatment, prior history and the related creep properties at different test condit-ions, in addition to the source process route and chemical composition details.Top-down approach has been adopted in designing the entity-relationship (E-R) model. The creep data is organized into the third normal form, and the entire system is divided into manageable modules. Coding for the system is done using Transact-SQL for data defin- ition, manipulation and control operations, and power script language for application development. This article briefly outlines the formulation of data base design, and the implemented E-R model, in addition , to the prese-ntation of various screen formats used for data entry and retrieval modules

RP-HPLC Method Development and Validation for Simultaneous Estimation of Duloxetin and Methylcobalamine in Combined Dosage Form

A simple, precise, accurate, simultaneous stability indicating RP-HPLC method for the estimation of DLU (Duloxetin) and MCB (Methylcobalamine) in combined dosage form was developed using Intersil-C18 (4.6 x 250mm, 5m) in an Isocratic mode with mobile phase comprising of Phosphate buffer (pH 4.5) The flow rate was 1 mL/ min and effluent was monitored at 255.0 nm. The retention times were found to be 5.32 min for DLU and 3.59 min for MCB. The assay exhibited a linear dynamic range of 20- 120 g/mL for DLU and 10- 60 g/mL for MCB. The calibration curves were linear (r 2 = 0.999 for DLU and r 2 = 0.999 for MCB) over the entire linear range. Mean % recovery was found to be 99.68 % for DLU and 100.3 % for MCB with % RSD was NMT 2 for both estimations which fully agrees with system suitability which is in good agreement with labeled amount of formulation. The % RSD for Intra- Day and Inter-Day Precision was NMT than 2 for both the drugs. The developed method was validated as per ICH guidelines

A rare case of congenital absence of permanent canines associated with other dental anomalies

Agenesis of permanent canines is a rare condition and that of both maxillary and mandibular permanent canines is extremely rare. Reports of such cases are very scarce in the literature. It may occur either isolated or in association with other dental anomalies. This paper reports an unusual case of agenesis of both the maxillary permanent canines and mandibular right permanent canine occurring in association with congenitally missing mandibular permanent central incisors and microdontic maxillary lateral incisors in a 10 year-old Indian male

Stereoselective synthesis of cis- and trans-bicyclo [6.3.0] undec-4-en-10-ones. Efficient precursors of 4-oxo-1,2-cyclopentane dipropanoic acids

Short syntheses of title compounds from cheap, readily available cis, cis-1,5-cyclooctadiene are described

Soil and Water Conservation Works through National Rural Employment Guarantee Scheme (NREGS) in Andhra Pradesh — An Analysis of Livelihood Impact

The impact of National Rural Employment Guarantee Scheme (NREGS) has been studied on rural livelihoods and the nature of soil and water conservation (SWC) works. NREGS is under implementation in almost all the rural districts of the country with the major objective of enhancing livelihoods through productive works. Rajasthan, Andhra Pradesh and Madhya Pradesh are the three states leading in scheme implementation with a large number of works, expenditure and employment. In Andhra Pradesh, soil and water conservation (SWC) works have accounted for over 80 per cent. The share of labour wages under the scheme has been 80 per cent with only 20 per cent for material, which is well within the prescribed norm of 40 per cent for the latter. The field study in the Ananthapur district has indicated that almost two-thirds of the beneficiaries are farmers. The scheme has brought down the migration levels from about 27 per cent to only 7 per cent in the study villages. The linear regression function has brought out that the number of family members participating in the NREGS is significantly influenced by income from other sources, family size and landholding. The NREGS earnings are being used mainly for food, education and health security. Although the scheme provides opportunity for 100 days of wage guarantee, the actual average employment is only for 25 days per household. Ideally, this gap needs to be bridged at least in the distress districts. The study has observed that SWC works in agricultural lands, especially in the rainfed areas need to be continued. However, some works require structural modifications for a better impact.Agricultural and Food Policy,

ENHANCED TRANSDERMAL PERMEABILITY OF TELMISARTAN BY A NOVEL NANOEMULSION GEL

Objective: Telmisartan is an angiotensin II type I receptor blocker antihypertensive agent with 42% oral bioavailability. The aim of the present investigation was to develop a nanoemulsion gel to enhance bioavailability of poorly water soluble Telmisartan.Methods: Different nanoemulsion components (oil, surfactant and co-surfactant) were selected on the basis of solubility and emulsification ability. Pseudotemary phase diagrams were constructed using aqueous titration method. Carbopol 934 was added as a gel matrix to convert nanoemulsion into nanoemulsion gel. Drug loaded nanoemulsions and nanoemulsion gels were characterized for particle size, viscosity, rheological behavior, thermodynamic stability studies and ex vivo permeation studies using rat skin. Transdermal permeation of Telmisartan from nanoemulsion gels was determined using Franz Diffusion cell.Results: The optimized nanoemulsion gel (NEG) contained Labrafil®M 2125 CS (14.3%) as oil, Acrysol®EL 135 (30.84%) as surfactant, Carbitol® (15.42%) as co-surfactant and (32.44%) water; 20 mg drug and 1% w/w carbopol. The ex vivo permeation profile of optimized formulation was compared to nanoemulsion and normal gel. Permeability parameters like steady-state flux (Jss), permeability coefficient (Kp), and enhancement ratio (Er) were significantly increased in nanoemulsion (NE) and nanoemulsion gel (NEG) as compared to conventional gel. There was a considerable improvement in bio availability for nanoemulsion gel compared to the conventional telemisartan gel.Conclusion: Nanoemulsion gel has significantly increased the bio-availability of the drug.Â

Study of Electrical and Thermal Behaviour of Li-ion Polymer Cells for Auxiliary Power Supply in Underwater Applications

Lithium  ion  polymer (Li-Po) battery technology is the latest technology for portable use and the most promising technology for exercise torpedoes. These batteries are technologically evolved from Lithium ion batteries. In this paper, extensive experimental studies on Li-Po cells which include studies on electrical characteristics during charge-discharge cycles, discharge at different C rates, self discharge throughout  charge stand, temperature profiles at the cathode and anode during the discharges, etc. are reported and discussed. The extensive electrical characterisation done on these cells indicates the capability of these cells for use as auxiliary power supply in underwater weapon applications.Defence Science Journal, 2012, 62(2), pp.127-131, DOI:http://dx.doi.org/10.14429/dsj.62.99

On the interesting course of dichloroketene addition to 1,5-dimethyl-1,5-cyclooctadiene

Reaction of dichloroketene with 1,5-dimethyl-1,5 COD 6 charters an eventful course to furnish novel tricyclic ketone 10, through the intermediacy of tricyclic hydroxy olefin 9, in which the two carbon atoms of dichloroketene form a bridge across the eight mem-bered ring

Hydrodynamic Performance and Acoustic Response of Ship Propeller

The aim of the paper is to predict the hydrodynamic performance and noise generated by the propeller at different advance ratio and the speed of the propeller. Three bladed, DTMB 4119 propeller model was created using the NACA66 modified line, a = 0.8 hydrofoil profile. ANSYS Workbench software is used for mesh generation and computational analysis. A large-eddy simulation turbulence model and Ffowcs Williams-Hawkings (FWH) acoustic model is used for all simulations. A moving reference frame is used to simulate the rotational effects of the propeller. The speed of the propeller is 792 rpm, the propeller being 0.2 m, and inlet velocity is varied to study the effect of the advance ratio. A transient analysis is carried out using a time step value of 0.0005 seconds and the total simulation time is 0.6 seconds. The hydrodynamic performance parameters are validated by comparing with the experimental data available in the literature. The sound pressure level (SPL) is plotted over the frequency range of 0 to 1000 Hz at different locations, speed, and an advance ratio of 0.5, 0.7, 0.833, and 0.9,1. The structural, acoustic and hydrodynamic behaviour of the propeller was predicted using a two-way fluid structure interaction at an advance ratio of 0.833. The major conclusions drawn from the analysis are that the sound pressure level values are increased at the propeller off-design conditions and varying with the receiver locations. The data generated from this study is useful for the designers to carry out further research in order to reduce the noise generated from the propeller

Delay Comparison for 16x16 Vedic Multiplier Using RCA and CLA

In any integrated chip compulsory adders are required because first they are fast and second are the less power consumption and delay. And at the same time multiplication process is also used in various applications. So as the speed of multiplier increases then the speed of processor also increases. And hence we are proposing the Vedic multiplier using these adders. Vedic multiplier is an ancient mathematics which uses mainly 16 sutras for its operation. In this project we are using “urdhva triyagbhyam” sutra to do our process. This paper proposes the Vedic multiplier using the adders ripple carry adder(RCA) and carry look ahead adder(CLA) and puts forward that CLA is better than RCA.The major parameters we are simulating here are number of slices and delay. The code is written by using Verilog and is implemented using Xilinx ISE Design Suite