42 research outputs found

    Influence of blend ratio on physical properties of oak tasar silk and acrylic blended spun yarn

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    In this study an attempt was made to utilize the oak tasar silk spinning waste through blending it with acrylic fibre and prepared yarn in mechanised spinning system.  The oak tasar silk and acrylic blended yarn were prepared on ring spinning machine with five different blend ratios viz. 100:0, 60:40, 50:50, 40:60 and 0:100. The prepared yarns were of medium to fine yarn count. Yarn Physical properties of yarns, unevenness and imperfections were studied and statistically analysed. Results revealed that the 100% acrylic and 50:50 tasar acrylic blended yarns had better properties as compared to 60:40 and 40:60. The addition of acrylic fibre content improved the physical properties, unevenness and imperfection of the blended yarns

    On-the-Job Stress: Interventions to Improve the Occupational Well-being of Policewomen in Assam, India

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    This article discusses the results of a study with an all-women police station and other police stations in Guwahati, Assam, India, considering their occupational stress and hazards related to womanhood issues. In this descriptive study, a sample of 30 women police was selected by purposive sampling and analyses were performed using responses to a questionnaire method and individual/group meetings. Well-being as well as levels of satisfaction leading to the commitment of the policewomen to their organization have been identified. A majority opined about experiencing occupational stress/hazards related to issues specific to womanhood. Ergonomic, on-the-job criteria, and appropriate design interventions, may address their stress and related concerns. Women’s hygiene specific issues in the workplace was a major concern. A few remedial design attempts have been proposed and some such improvements have been implemented by authorities to upgrade the women’s police station. In addition to the physical and mental well-being of existing policewomen enabling them to perform their duties effectively and efficiently, such sympathetic developments have created a positive niche to motivate more young women to enter the police force

    Rural Women Artists: A Visual Analysis of the Mural Art Forms of Santhal Pargana, Jharkhand, India

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    Women are the pioneers of traditional mural art practices in rural India. Warli art, Gond art, and Madhubani paintings are examples of their artworks. The women belonging to the Santhal region in eastern India, are highly skilled in rich rural vernacular art. Murals are generally created by them during local festivals and marriage ceremonies. The women of six districts that comprise the Santhal Pargana (Dumka, Godda, Deoghar, Jamtara, Pakur and Sahibganj), decorate their mud houses during these occasions with visual borders and motifs. A pilot study was carried out with the women artists to research these murals. The framework for the visual analysis is based on distinct symmetry operations such as translation, rotation, reflection, and glide reflection. This paper examines the various artistic expressions of the rural women of Santhal Pargana

    Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients

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    <p>Abstract</p> <p>Background</p> <p>Molecular chaperones have been shown to be important in the growth of the malaria parasite <it>Plasmodium falciparum </it>and inhibition of chaperone function by pharmacological agents has been shown to abrogate parasite growth. A recent study has demonstrated that clinical isolates of the parasite have distinct physiological states, one of which resembles environmental stress response showing up-regulation of specific molecular chaperones.</p> <p>Methods</p> <p>Chaperone networks operational in the distinct physiological clusters in clinical malaria parasites were constructed using cytoscape by utilizing their clinical expression profiles.</p> <p>Results</p> <p>Molecular chaperones show distinct profiles in the previously defined physiologically distinct states. Further, expression profiles of the chaperones from different cellular compartments correlate with specific patient clusters. While cluster 1 parasites, representing a starvation response, show up-regulation of organellar chaperones, cluster 2 parasites, which resemble active growth based on glycolysis, show up-regulation of cytoplasmic chaperones. Interestingly, cytoplasmic Hsp90 and its co-chaperones, previously implicated as drug targets in malaria, cluster in the same group. Detailed analysis of chaperone expression in the patient cluster 2 reveals up-regulation of the entire Hsp90-dependent pro-survival circuitries. In addition, cluster 2 also shows up-regulation of <it>Plasmodium </it>export element (PEXEL)-containing Hsp40s thought to have regulatory and host remodeling roles in the infected erythrocyte.</p> <p>Conclusion</p> <p>In all, this study demonstrates an intimate involvement of parasite-encoded chaperones, PfHsp90 in particular, in defining pathogenesis of malaria.</p

    Proteomics of Trypanosoma evansi Infection in Rodents

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    infection using mass spectrometry (MS). in mice infected with camel isolate. Homology driven searches for protein identification from MS/MS data led to most of the matches arising from related Trypanosoma species. Proteins identified belonged to various functional categories including metabolic enzymes; DNA metabolism; transcription; translation as well as cell-cell communication and signal transduction. TCA cycle enzymes were strikingly missing, possibly suggesting their low abundances. The clinical proteome revealed the presence of known and potential drug targets such as oligopeptidases, kinases, cysteine proteases and more. infections

    Clinical Proteomics of the Neglected Human Malarial Parasite Plasmodium vivax

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    Recent reports highlight the severity and the morbidity of disease caused by the long neglected malaria parasite Plasmodium vivax. Due to inherent difficulties in the laboratory-propagation of P. vivax, the biology of this parasite has not been adequately explored. While the proteome of P. falciparum, the causative agent of cerebral malaria, has been extensively explored from several sources, there is limited information on the proteome of P. vivax. We have, for the first time, examined the proteome of P. vivax isolated directly from patients without adaptation to laboratory conditions. We have identified 153 proteins from clinical P. vivax, majority of which do not show homology to any previously known gene products. We also report 29 new proteins that were found to be expressed in P. vivax for the first time. In addition, several proteins previously implicated as anti-malarial targets, were also found in our analysis. Most importantly, we found several unique proteins expressed by P. vivax.This study is an important step in providing insight into physiology of the parasite under clinical settings

    FORMULATION AND EVALUATION OF HERBAL LIPSTICK PREPARED FROM ROSA ‘Papa meilland’

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    Cosmetics are in advanced demand since one time till nowadays as herbal care products are in great demand. Lipstick phrasings are most extensively used to enhance the beauty and appearance of lips and to add a pressing effect on facial makeup. It's delicate to apply Lipstick on dried, chapped, cracked, infected or diseased lips with blisters and lesions. They use herbal camo for the purpose of curing unwanted topical conditions and ameliorating the appearance and beauty of lips with this end and objects a herbal medication was made to formulate and estimate herbal camo by using rose Papa meilland (powder), olive oil, naturally occurring excipients. Rose Papa meilland contains composites substantially peonidin-3-Osophoroside, peonidin and peonidin-3-O’Glucoside, used as a colouring agent. The herbal Lipstick was estimated for their parcels similar to spreading, covering property and glossiness and set up to be a better and satisfactory product to give seductive beautification with remedial effect. The herbal camo with natural constituents can serve as provident and effectiveness to ornamental herbal care and beauty product. Due to the colorful adverse goods of available synthetic medication, the present work was conceived by us to formulate a herbal powder having minimum or no side goods which will considerably use by the women of our communities with great surety and satisfaction

    Detection of Heavy Elements in the Pulp of Snow-Capped Seabuckthorn Medicinal Plant Using Emission Spectroscopy

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    Seabuckthorn (SBT) is a very popular plant in high-altitude cold desert areas which has tremendous medicinal properties. The present study used Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) to analyze SBT fruit pulp extracts concerning heavy metals Potassium, Phosphorus, Calcium, Magnesium, Copper, Manganese, Zinc, Boron, Nickel, Cadmium and Lead. This study found that heavy metals in SBT herbal plant was in the range of 8.65 g/kg Potassium, 1.74 g/kg Phosphorus, 0.692 g/kg Calcium, 0.546 g/kg Magnesium, 39.45 mg/kg Iron, 5.468 mg/kg Copper, 12.68 mg /kg Manganese, 8.25 mg/kg Zinc, 11.36 mg/kg Boron, 0.35 mg/kg Nickel, 0.021 mg/kg Cadmium and 0.027 mg/kg Lead. The findings of this study were compared with the prescribed limits of these metals in WHO guidelines and the content of all these heavy metals was found to be within safe limits

    Antiglycation, Antioxidant and Antidiabetic Activity of Strawberry (Fragaria × ananassa) Fruits during Ripening Stages

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    ABSTRACT In present study, antiglycation, anti-oxidant and anti-diabetic potential of three different stages [Green (I), Greenish White (II), Whitish Red (III)] of strawberry was investigated. Time bound antiglycation activity of the extract was assayed by incubating guanosine with glucose or fructose with or without extract. To determine the anti-oxidant activity, antioxidant enzyme assays (Catalase, Peroxidase, Polyphenol oxidase) and free radical scavenging assays (Xanthine oxidase, superoxide anion free radical scavenging) were performed while anti-diabetic assays were carried out through measurement of inhibition of α-glucosidase and α-amylase activities. Maximum UV absorbance for glycation reactions was observed for 24 hrs. The superoxide scavenging activity of 100 µg fruit extract of stage I, II and III was found to be 4.35%, 18.74% and 16.28% respectively. Xanthine oxidase inhibitory activity showed a maximum percent inhibition of 60.68% at concentration of 702.46 µg ± 1.53 at stage III. IC 50 value for α-glucosidase and α -amylase activity at stage III was found to be 154.27 µg ± 33.12 and 195.28 µg ± 13.30 respectively. Present study demonstrates that strawberry during ripening stages exhibits potent antiglycation, antioxidant and anti-diabetic activities. Ripening stages of strawberry should further be investigated for mechanisms of antiglycation, antioxidant and anti-diabetic activities for management of diabetes
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