Bio-Processes of the Oxidation Ditch When Subjected to a Sub-Arctic Climate

Alaska's far northern area is sparsely populated primarily because of a severe climate which varies from northern temperate to Arctic. Construction and power costs are high. Skilled operating personnel are scarce and expensive, if available. Receiving streams are said to be delicate, particularily in the winter, when little possibility for reaeration exists due to a total ice cover. The oxidation ditch modification of the extended aeration activated sludge process appears to be well suited for the treatment of wastes in this environment. Past operating data on a plant of this type located in Interior Alaska (near Fairbanks) indicated it may be well suited to treat small volumes of domestic waste economically, with low sludge production, and minimal sensitivity to low temperatures.The work reported on herein was done under Contract No. RFP DACA 897l- R-0006 from the U. S. Army Cold Regions Research and Engineering Laboratory, Hanover, New Hampshire

Spin dynamics and frequency dependence of magnetic damping study in soft ferromagnetic FeTaC film with a stripe domain structure

Perpendicular magnetic anisotropy (PMA) and low magnetic damping are the key factors for the free layer magnetization switching by spin transfer torque technique in magnetic tunnel junction devices. The magnetization precessional dynamics in soft ferromagnetic FeTaC thin film with a stripe domain structure was explored in broad band frequency range by employing micro-strip ferromagnetic resonance technique. The polar angular variation of resonance field and linewidth at different frequencies have been analyzed numerically using Landau-Lifshitz-Gilbert equation by taking into account the total free energy density of the film. The numerically estimated parameters Land\'{e} $g$-factor, PMA constant, and effective magnetization are found to be 2.1, 2$\times10^{5}$ erg/cm$^{3}$ and 7145 Oe, respectively. The frequency dependence of Gilbert damping parameter ($\alpha$) is evaluated by considering both intrinsic and extrinsic effects into the total linewidth analysis. The value of $\alpha$ is found to be 0.006 at 10 GHz and it increases with decreasing precessional frequency.Comment: 5 Pages, 6 Figures, Regular Submissio

Exploratory Analysis of Highly Heterogeneous Document Collections

We present an effective multifaceted system for exploratory analysis of highly heterogeneous document collections. Our system is based on intelligently tagging individual documents in a purely automated fashion and exploiting these tags in a powerful faceted browsing framework. Tagging strategies employed include both unsupervised and supervised approaches based on machine learning and natural language processing. As one of our key tagging strategies, we introduce the KERA algorithm (Keyword Extraction for Reports and Articles). KERA extracts topic-representative terms from individual documents in a purely unsupervised fashion and is revealed to be significantly more effective than state-of-the-art methods. Finally, we evaluate our system in its ability to help users locate documents pertaining to military critical technologies buried deep in a large heterogeneous sea of information.Comment: 9 pages; KDD 2013: 19th ACM SIGKDD Conference on Knowledge Discovery and Data Minin

Numerical calculations on the new approach to the cascade theory - I

In the new approach to the cascade theory suggested by Alladi Ramakrishnan and one of us (S. K. S.), we deal with the number of electrons produced between 0 and t in a soft cascade, each of these electrons having an energy greater than E at the point of its production as contrasted with the usual approach where we are interested in the number of electrons with energy greater than E at t. We present here numerical calculations of the mean numbers on the basis of the new approach

Chemical approaches to the re-structuring of proteins

Methodologies for protein re-structuring have been developed enabling site specific side chain modification to either coded or non-coded residues. Procedures for the modification of the protein profile by attachment of either pendants or structural motifs have been delineated. Selectivity has been demonstrated on the basis of modulation of the -CH2- spacer, which interposes the functional group and the peptide backbone

Re-entrant spin glass and magnetoresistance in Co_{0.2}Zn_{0.8}Fe_{1.6}Ti_{0.4}O_4 spinel oxide

We have investigated the static and dynamic response of magnetic clusters in Co_{0.2}Zn_{0.8}Fe_{1.6}Ti_{0.4}O_4 spinel oxide, where a sequence of magnetic phase transitions, i.e., paramagnetic (PM) to ferromagnetic at T_{C} $\leq$ 270K and ferromagnetic to canted spin glass state at T_f$$\leq$ 125K is observed

Mapping of household vulnerability and identification of adaptation strategies in dryland systems of South Asia, Research Report No. 67

Low amount and high variability of rainfall in South Asian dryland production system have affected the livelihood of small and marginal households. Therefore, a marginal change in the climate could challenge the livelihood resilience of millions of farmers and affect the healthy ecosystem function in South Asia. The CGIAR Consortium Research Program on Dryland Systems (DS) focuses on DS across the world in order to tackle these problems. The overall emphasis of the research involves understanding the problem, identifying and demonstrating technologies and searching for mechanisms to promote the adoption of promising technologies. In South Asia, the program selected six districts in Andhra Pradesh (Anantapur and Kurnool), Karnataka (Bijapur) and Western Rajasthan (Jaisalmer, Barmer, and Jodhpur) as action sites..

Cellular kinetics: A clinical and computational review of CAR-T cell pharmacology

To the extent that pharmacokinetics influence the effectiveness of nonliving therapeutics, so too do cellular kinetics influence the efficacy of Chimeric Antigen Receptor (CAR) -T cell therapy. Like conventional therapeutics, CAR-T cell therapies undergo a distribution phase upon administration. Unlike other therapeutics, however, this distribution phase is followed by subsequent phases of expansion, contraction, and persistence. The magnitude and duration of these phases unequivocally influence clinical outcomes. Furthermore, the “pharmacodynamics” of CAR-T cells is truly dynamic, as cells can rapidly become exhausted and lose their therapeutic efficacy. Mathematical models are among the translational tools commonly applied to assess, characterize, and predict the complex cellular kinetics and dynamics of CAR-T cells. Here, we provide a focused review of the cellular kinetics of CAR-T cells, the mechanisms underpinning their complexity, and the mathematical modeling approaches used to interrogate them