2,033 research outputs found
Bio-Processes of the Oxidation Ditch When Subjected to a Sub-Arctic Climate
Alaska's far northern area is sparsely populated primarily because of a
severe climate which varies from northern temperate to Arctic. Construction
and power costs are high. Skilled operating personnel are scarce and
expensive, if available. Receiving streams are said to be delicate, particularily
in the winter, when little possibility for reaeration exists due to a total ice cover. The oxidation ditch modification of the extended aeration activated sludge process appears to be well suited for the
treatment of wastes in this environment. Past operating data on a plant
of this type located in Interior Alaska (near Fairbanks) indicated it may
be well suited to treat small volumes of domestic waste economically,
with low sludge production, and minimal sensitivity to low temperatures.The work reported on herein was done under Contract No. RFP DACA 897l-
R-0006 from the U. S. Army Cold Regions Research and Engineering
Laboratory, Hanover, New Hampshire
Spin dynamics and frequency dependence of magnetic damping study in soft ferromagnetic FeTaC film with a stripe domain structure
Perpendicular magnetic anisotropy (PMA) and low magnetic damping are the key
factors for the free layer magnetization switching by spin transfer torque
technique in magnetic tunnel junction devices. The magnetization precessional
dynamics in soft ferromagnetic FeTaC thin film with a stripe domain structure
was explored in broad band frequency range by employing micro-strip
ferromagnetic resonance technique. The polar angular variation of resonance
field and linewidth at different frequencies have been analyzed numerically
using Landau-Lifshitz-Gilbert equation by taking into account the total free
energy density of the film. The numerically estimated parameters Land\'{e}
-factor, PMA constant, and effective magnetization are found to be 2.1,
2 erg/cm and 7145 Oe, respectively. The frequency
dependence of Gilbert damping parameter () is evaluated by considering
both intrinsic and extrinsic effects into the total linewidth analysis. The
value of is found to be 0.006 at 10 GHz and it increases with
decreasing precessional frequency.Comment: 5 Pages, 6 Figures, Regular Submissio
Exploratory Analysis of Highly Heterogeneous Document Collections
We present an effective multifaceted system for exploratory analysis of
highly heterogeneous document collections. Our system is based on intelligently
tagging individual documents in a purely automated fashion and exploiting these
tags in a powerful faceted browsing framework. Tagging strategies employed
include both unsupervised and supervised approaches based on machine learning
and natural language processing. As one of our key tagging strategies, we
introduce the KERA algorithm (Keyword Extraction for Reports and Articles).
KERA extracts topic-representative terms from individual documents in a purely
unsupervised fashion and is revealed to be significantly more effective than
state-of-the-art methods. Finally, we evaluate our system in its ability to
help users locate documents pertaining to military critical technologies buried
deep in a large heterogeneous sea of information.Comment: 9 pages; KDD 2013: 19th ACM SIGKDD Conference on Knowledge Discovery
and Data Minin
Numerical calculations on the new approach to the cascade theory - I
In the new approach to the cascade theory suggested by Alladi Ramakrishnan and one of us (S. K. S.), we deal with the number of electrons produced between 0 and t in a soft cascade, each of these electrons having an energy greater than E at the point of its production as contrasted with the usual approach where we are interested in the number of electrons with energy greater than E at t. We present here numerical calculations of the mean numbers on the basis of the new approach
Chemical approaches to the re-structuring of proteins
Methodologies for protein re-structuring have been developed enabling site specific side chain modification to either coded or non-coded residues. Procedures for the modification of the protein profile by attachment of either pendants or structural motifs have been delineated. Selectivity has been demonstrated on the basis of modulation of the -CH2- spacer, which interposes the functional group and the peptide backbone
Re-entrant spin glass and magnetoresistance in Co_{0.2}Zn_{0.8}Fe_{1.6}Ti_{0.4}O_4 spinel oxide
We have investigated the static and dynamic response of magnetic clusters in
Co_{0.2}Zn_{0.8}Fe_{1.6}Ti_{0.4}O_4 spinel oxide, where a sequence of magnetic
phase transitions, i.e., paramagnetic (PM) to ferromagnetic at T_{C}
270K and ferromagnetic to canted spin glass state at T_f\leq$ 125K is
observed
Mapping of household vulnerability and identification of adaptation strategies in dryland systems of South Asia, Research Report No. 67
Low amount and high variability of rainfall in South Asian dryland production system have affected the livelihood of small and marginal households. Therefore, a marginal change in the climate could challenge the livelihood resilience of millions of farmers and affect the healthy ecosystem function in South Asia. The CGIAR Consortium Research Program on Dryland Systems (DS) focuses on DS across the world in order to tackle these problems. The overall emphasis of the research involves understanding the problem, identifying and demonstrating technologies and searching for mechanisms to promote the adoption of promising technologies. In South Asia, the program selected six districts in Andhra Pradesh (Anantapur and Kurnool), Karnataka (Bijapur) and Western Rajasthan (Jaisalmer, Barmer, and Jodhpur) as action sites..
Cellular kinetics: A clinical and computational review of CAR-T cell pharmacology
To the extent that pharmacokinetics influence the effectiveness of nonliving therapeutics, so too do cellular kinetics influence the efficacy of Chimeric Antigen Receptor (CAR) -T cell therapy. Like conventional therapeutics, CAR-T cell therapies undergo a distribution phase upon administration. Unlike other therapeutics, however, this distribution phase is followed by subsequent phases of expansion, contraction, and persistence. The magnitude and duration of these phases unequivocally influence clinical outcomes. Furthermore, the “pharmacodynamics” of CAR-T cells is truly dynamic, as cells can rapidly become exhausted and lose their therapeutic efficacy. Mathematical models are among the translational tools commonly applied to assess, characterize, and predict the complex cellular kinetics and dynamics of CAR-T cells. Here, we provide a focused review of the cellular kinetics of CAR-T cells, the mechanisms underpinning their complexity, and the mathematical modeling approaches used to interrogate them
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