Constraining Dark Matter Substructure With Gaia Wide Binaries

We use a catalogue of stellar binaries with wide separations (up to 1 pc) identified by the Gaia satellite to constrain the presence of extended substructure within the Milky Way galaxy. Heating of the binaries through repeated encounters with substructure results in a characteristic distribution of binary separations, allowing constraints to be placed independent of the formation mechanism of wide binaries. Across a wide range of subhalo density profiles, we show that subhalos with masses $\gtrsim 65 \ M_\odot$ and characteristic length scales similar to the separation of these wide binaries cannot make up 100% of the Galaxy's dark matter. Constraints weaken for subhalos with larger length scales and are dependent on their density profiles. For such large subhalos, higher central densities lead to stronger constraints. Subhalos with density profiles similar to those expected from cold dark matter must be at least $\sim 5,000$ times denser than predicted by simulation to be constrained by the wide binary catalogue.Comment: 21 pages, 23 figure

Understanding Paramagnetic Spin Correlations in the Spin-Liquid Pyrochlore Tb2Ti2O7

Recent elastic and inelastic neutron scattering studies of the highly frustrated pyrochlore antiferromagnet Tb2Ti2O7 have shown some very intriguing features that cannot be modeled by the local classical Ising model, naively expected to describe this system at low temperatures. Using the random phase approximation to take into account fluctuations between the ground state doublet and the first excited doublet, we successfully describe the elastic neutron scattering pattern and dispersion relations in Tb2Ti2O7, semi-quantitatively consistent with experimental observations.Comment: revtex4, 4 pages, 1 Color+ 2 BW figure

Point Absorber Limits to Future Gravitational-Wave Detectors

High-quality optical resonant cavities require low optical loss, typically on the scale of parts per million. However, unintended micron-scale contaminants on the resonator mirrors that absorb the light circulating in the cavity can deform the surface thermoelastically, and thus increase losses by scattering light out of the resonant mode. The point absorber effect is a limiting factor in some highpower cavity experiments, for example, the Advanced LIGO gravitational wave detector. In this Letter, we present a general approach to the point absorber effect from first principles and simulate its contribution to the increased scattering. The achievable circulating power in current and future gravitational-wave detectors is calculated statistically given different point absorber configurations. Our formulation is further confirmed experimentally in comparison with the scattered power in the arm cavity of Advanced LIGO measured by in-situ photodiodes. The understanding presented here provides an important tool in the global effort to design future gravitational wave detectors that support high optical power, and thus reduce quantum noise

Epithelial cell–derived secreted and transmembrane 1a signals to activated neutrophils during pneumococcal pneumonia

Airway epithelial cell responses are critical to the outcome of lung infection. In this study, we aimed to identify unique contributions of epithelial cells during lung infection. To differentiate genes induced selectively in epithelial cells during pneumonia, we compared genome-wide expression profiles from three sorted cell populations: epithelial cells from uninfected mouse lungs, epithelial cells from mouse lungs with pneumococcal pneumonia, and nonepithelial cells from those same infected lungs. Of 1,166 transcripts that were more abundant in epithelial cells from infected lungs compared with nonepithelial cells from the same lungs or from epithelial cells of uninfected lungs, 32 genes were identified as highly expressed secreted products. Especially strong signals included two related secreted and transmembrane (Sectm) 1 genes, Sectm1a and Sectm1b. Refinement of sorting strategies suggested that both Sectm1 products were induced predominantly in conducting airway epithelial cells. Sectm1 was induced during the early stages of pneumococcal pneumonia, and mutation of NF-kB RelA in epithelial cells did not diminish its expression. Instead, type I IFN signaling was necessary and sufficient for Sectm1 induction in lung epithelial cells, mediated by signal transducer and activator of transcription 1. For target cells, Sectm1a bound to myeloid cells preferentially, in particular Ly6GbrightCD11bbright neutrophils in the infected lung. In contrast, Sectm1a did not bind to neutrophils from uninfected lungs. Sectm1a increased expression of the neutrophil-attracting chemokine CXCL2 by neutrophils from the infected lung. We propose that Sectm1a is an epithelial product that sustains a positive feedback loop amplifying neutrophilic inflammation during pneumococcal pneumonia

Genetically encoded reporters for hyperpolarized xenon magnetic resonance imaging

Magnetic resonance imaging (MRI) enables high-resolution non-invasive observation of the anatomy and function of intact organisms. However, previous MRI reporters of key biological processes tied to gene expression have been limited by the inherently low molecular sensitivity of conventional ^1H MRI. This limitation could be overcome through the use of hyperpolarized nuclei, such as in the noble gas xenon, but previous reporters acting on such nuclei have been synthetic. Here, we introduce the first genetically encoded reporters for hyperpolarized ^(129)Xe MRI. These expressible reporters are based on gas vesicles (GVs), gas-binding protein nanostructures expressed by certain buoyant microorganisms. We show that GVs are capable of chemical exchange saturation transfer interactions with xenon, which enables chemically amplified GV detection at picomolar concentrations (a 100- to 10,000-fold improvement over comparable constructs for ^1H MRI). We demonstrate the use of GVs as heterologously expressed indicators of gene expression and chemically targeted exogenous labels in MRI experiments performed on living cells

A Neutron Star Binary Merger Model for GW170817/GRB170817a/SSS17a

The merging neutron star gravitational wave event GW170817 has been observed throughout the entire electromagnetic spectrum from radio waves to $\gamma$-rays. The resulting energetics, variability, and light curves are shown to be consistent with GW170817 originating from the merger of two neutron stars, in all likelihood followed by the prompt gravitational collapse of the massive remnant. The available $\gamma$-ray, X-ray and radio data provide a clear probe for the nature of the relativistic ejecta and the non-thermal processes occurring within, while the ultraviolet, optical and infrared emission are shown to probe material torn during the merger and subsequently heated by the decay of freshly synthesized $r$-process material. The simplest hypothesis that the non-thermal emission is due to a low-luminosity short $\gamma$-ray burst (sGRB) seems to agree with the present data. While low luminosity sGRBs might be common, we show here that the collective prompt and multi-wavelength observations are also consistent with a typical, powerful sGRB seen off-axis. Detailed follow-up observations are thus essential before we can place stringent constraints on the nature of the relativistic ejecta in GW170817.Comment: 9 pages, 5 figures, accepted to ApJ Letter

Theory of paramagnetic scattering in highly frustrated magnets with long-range dipole-dipole interactions: The case of the Tb2Ti2O7, pyrochlore antiferromagnet

Highly frustrated antiferromagnets composed of magnetic rare-earth moments are currently attracting much experimental and theoretical interest. Rare-earth ions generally have small exchange interactions and large magnetic moments. This makes it necessary to understand in detail the role of long-range magnetic dipole-dipole interactions in these systems, in particular in the context of spin-spin correlations that develop in the paramagnetic phase, but are often unable to condense into a conventional long-range magnetic ordered phase. This scenario is most dramatically emphasized in the frustrated pyrochlore antiferromagnet material Tb2Ti207 which does not order down to 50 mK despite an antiferromagnetic Curie-Weiss temperature Tcw ~ -20 K. In this paper we report results from mean-field theory calculations of the paramagnetic elastic neutron-scattering in highly frustrated magnetic systems with long-range dipole-dipole interactions, focusing on the Tb2Ti207 system. Modeling Tb2Ti207 as an antiferromagnetic Ising pyrochlore, we find that the mean-field paramagnetic scattering is inconsistent with the experimentally observed results. Through simple symmetry arguments we demonstrate that the observed paramagnetic correlations in Tb2Ti207 are precluded from being generated by any spin Hamiltonian that considers only Ising spins, but are qualitatively consistent with Heisenberg-like moments. Explicit calculations of the paramagnetic scattering pattern for both Ising and Heisenberg models, which include finite single-ion anisotropy, support these claims. We offer suggestions for reconciling the need to restore spin isotropy with the Ising like structure suggested by the single-ion properties of Tb3+.Comment: Revtex4, 18 pages, 3 eps figures (2 color figures). Change in title and emphasis on Tb2Ti2O7 only. Spin-ice material removed, to appear in a later publicatio

Electromagnetic Evidence that SSS17a is the Result of a Binary Neutron Star Merger

11 hours after the detection of gravitational wave source GW170817 by the Laser Interferometer Gravitational-Wave Observatory and Virgo Interferometers, an associated optical transient SSS17a was discovered in the galaxy NGC 4993. While the gravitational wave data indicate GW170817 is consistent with the merger of two compact objects, the electromagnetic observations provide independent constraints of the nature of that system. Here we synthesize all optical and near-infrared photometry and spectroscopy of SSS17a collected by the One-Meter Two-Hemisphere collaboration. We find that SSS17a is unlike other known transients. The source is best described by theoretical models of a kilonova consisting of radioactive elements produced by rapid neutron capture (the r-process). We find that SSS17a was the result of a binary neutron star merger, reinforcing the gravitational wave result.Comment: 21 pages, 4 figures, accepted to Scienc

Characterization of edge damage induced on REBCO superconducting tape by mechanical slitting

Rare-earth barium-copper-oxide (REBCO) superconductors are high-field superconductors fabricated in a tape geometry that can be utilized in magnet applications well in excess of 20 T. Due to the multilayer architecture of the tape, delamination is one cause of mechanical failure in REBCO tapes. During a mechanical slitting step in the manufacturing process, edge cracks can be introduced into the tape. These cracks are thought to be potential initiation sites for crack propagation in the tapes when subjected to stresses in the fabrication and operation of magnet systems. We sought to understand which layers were the mechanically weakest by locating the crack initiation layer and identifying the geometrical conditions of the slitter that promoted or suppressed crack formation. The described cracking was investigated by selectively etching and characterizing each layer with scanning electron microscopy, laser confocal microscopy, and digital image analysis. Our analysis showed that the average crack lengths in the REBCO, LaMnO3 (LMO) and Al2O3 layers were 34 μm, 28 μm, and 15 μm, respectively. The total number of cracks measured in 30mmof wire length was between 3000 and 5700 depending on the layer and their crack densities were 102 cracks mm-1 for REBCO, 108 cracks mm-1 for LMO, and 183 cracks mm-1 for Al2O3. These results indicated that there are separate crack initiation mechanisms for the REBCO and the LMO layers, as detailed in the paper. With a better understanding of the crack growth behavior exhibited by REBCO tapes, the fabrication process can be improved to provide a more mechanically stable and cost-effective superconductor

Aria 1.5 : user manual.

Aria is a Galerkin finite element based program for solving coupled-physics problems described by systems of PDEs and is capable of solving nonlinear, implicit, transient and direct-to-steady state problems in two and three dimensions on parallel architectures. The suite of physics currently supported by Aria includes the incompressible Navier-Stokes equations, energy transport equation, species transport equations, nonlinear elastic solid mechanics, and electrostatics as well as generalized scalar, vector and tensor transport equations. Additionally, Aria includes support for arbitrary Lagrangian-Eulerian (ALE) and level set based free and moving boundary tracking. Coupled physics problems are solved in several ways including fully-coupled Newton's method with analytic or numerical sensitivities, fully-coupled Newton-Krylov methods, fully-coupled Picard's method, and a loosely-coupled nonlinear iteration about subsets of the system that are solved using combinations of the aforementioned methods. Error estimation, uniform and dynamic h-adaptivity and dynamic load balancing are some of Aria's more advanced capabilities. Aria is based on the Sierra Framework