Daytime Napping and Nighttime Sleep During Pregnancy and Preterm Birth in Iran

Objectives: This study investigated the relationship between sleep quality during pregnancy and preterm birth. Methods: This longitudinal study was conducted between August 2018 and May 2019. The participants were 150 pregnant women who had been referred to 7 healthcare centers in the city of Qazvin, Iran and met the inclusion criteria. The Petersburg Sleep Quality Index, the Epworth Sleepiness Scale, and 2 questions about daytime sleep status and a demographic questionnaire were administered at 14-18 weeks and 28-32 weeks of gestation. Data were analyzed using the Mann-Whitney test, the Fisher exact test, and univariate and multivariable logistic regression. Results: In the present study, poor sleep quality affected 84.7% of the participants at 14-18 weeks and 93.3% at 28-32 weeks of gestation. The final model for preterm birth prediction incorporated age and the Petersburg Sleep Quality Index score in the second and third trimesters. Preterm birth increased by 14% with each unit increase in age. With each unit increase in the Petersburg Sleep Quality Index score in the second and third trimesters, preterm birth increased by 42% and 28%, respectively, but the p-values of these factors were not significant. Conclusions: Although a significant percentage of pregnant women had poor sleep quality, no significant relationship was found between sleep quality during pregnancy and preterm birth

Antibacterial, physical and mechanical properties of bonding agent containing synthesized Zinc Dimethacrylate

The aim of this study includes synthesis of zinc dimethacrylate ionomer (ZDMA) by a new method, incorporate it into resin bonding and evaluate its antibacterial, physical and mechanical properties. Resin adhesives containing 0 to 5% wt of ZDMA was produced and the following tests were accomplished: A: Antibacterial test: 1.Direct contact test. 2.Material aging; in both of them the bacterial colony counting were performed. B: Physical test: 1.Degree of conversion (D.C). 2.Evaluating the amount of released Zinc ion release in aqueous medium. C: Mechanical test: 1.Compressive strength test. 2.Shear bond test (enamel and dentine separately). The obtained results were statistically analyzed using One Way ANOVA and LSD post hoc test (?=0.05). The anti-bacterial test revealed that all the ZDMA containing groups significantly reduced the amount of Streptococcus Mutans bacteria. Moreover, the D.C in all ZDMA groups was enhanced. Furthermore, ion release analysis revealed noticeable stability of Zn2+ in samples, as in the 5wt.% group it was even after nine cycle of 24h wash. On the other hand, the compressive strength was significantly reduced just in the 5% ZDMA group while the other groups were superior comparing to the control. In addition, there was no significant difference among the enamel shear bond strength of the groups. However, about the dentine shear bond strength, only the 5% ZDMA group was significantly higher than the control. Low percentages of ZDMA in adhesive could impart anti-bacterial efficacy without challenging its mechanical and physical properties

Effect of Perineal Massage with Ostrich Oil on the Episiotomy and Lacerations in Nulliparous Women: A Randomized Controlled Clinical Trial

Background: Perineal lacerations resulting from vaginal delivery may cause short and long complications, which lead to some problems in women after the delivery. Ostrich oil is safe for use in skincare and beauty products. The aim of this study was to examine the effect of perineal massage with Ostrich oil on the episiotomy and lacerations in nulliparous women. Materials and Methods: This single‑blind randomized controlled trial was conducted on 77 nulliparous women referred to Razi Hospital in Qazvin (Iran) from May to December 2018. After screening of potential participants, 80 out of 105 pregnant women were selected by convenience sampling and were assigned into the intervention and control groups by block randomization technique. In the intervention group, participants received a perineal massage with Ostrich oil in the active phase and the second stage of labor. The rates of episiotomy and perineal laceration were compared between the two groups. Data were analyzed using Chi-square, t-test and Mann-Whitney. Results: Perineal massage with Ostrich oil in the intervention group significantly decreased the rate of episiotomy compared to the control group (2 = 18.32, df = 1, p < 0.001). However, there was no statistically significant difference in perineal lacerations between the two groups. Conclusions: The results revealed that perineal massage with Ostrich oil could be recommended as an effective, safe, and inexpensive method to improve the rate of episiotomy in vaginal delivery. Perineal massage can be performed by midwives in the first and second stages of labor

Effect of Perineal Massage with Ostrich Oil on the Episiotomy and Lacerations in Nulliparous Women: A Randomized Controlled Clinical Trial

Background: Perineal lacerations resulting from vaginal delivery may cause short and long complications, which lead to some problems in women after the delivery. Ostrich oil is safe for use in skincare and beauty products. The aim of this study was to examine the effect of perineal massage with Ostrich oil on the episiotomy and lacerations in nulliparous women. Materials and Methods: This single‑blind randomized controlled trial was conducted on 77 nulliparous women referred to Razi Hospital in Qazvin (Iran) from May to December 2018. After screening of potential participants, 80 out of 105 pregnant women were selected by convenience sampling and were assigned into the intervention and control groups by block randomization technique. In the intervention group, participants received a perineal massage with Ostrich oil in the active phase and the second stage of labor. The rates of episiotomy and perineal laceration were compared between the two groups. Data were analyzed using Chi-square, t-test and Mann-Whitney. Results: Perineal massage with Ostrich oil in the intervention group significantly decreased the rate of episiotomy compared to the control group (2 = 18.32, df = 1, p < 0.001). However, there was no statistically significant difference in perineal lacerations between the two groups. Conclusions: The results revealed that perineal massage with Ostrich oil could be recommended as an effective, safe, and inexpensive method to improve the rate of episiotomy in vaginal delivery. Perineal massage can be performed by midwives in the first and second stages of labor

The analgesic effect of curcumin and nano-curcumin in clinical and preclinical studies: a systematic review and meta-analysis

Chronic pain remains a treatment challenge. Curcumin, a natural plant product found in the Curcuma genus, has been shown to possess anti-inflammatory, antioxidant, and neuroprotective properties. In this systematic review and meta-analysis, we aimed to evaluate the efficacy of curcumin and nano-curcumin for treating chronic pain in clinical and preclinical studies. A systematic search was performed through PubMed, SCOPUS, Web of Science Core Collection, Cochrane, and Google Scholar up to April 1, 2023, using relevant keywords. Trials that met the inclusion criteria were included in this study. We applied the mean difference (MD) or standardized mean difference (SMD) in random or fixed-effects models to analyze the impact of combined trials. We also evaluated the potential risk of bias using the Higgins method for clinical studies and the SYRCLE Risk of Bias tool for animal studies. Our meta-analysis included 59 studies, comprising 29 animal studies and 30 clinical studies. Curcumin strongly reduced pain in preclinical studies, and both the intraperitoneal (SMD = 1.48; 95% CI, 0.81 to 2.14; p </p