Figure 3

<p>A) LD plot of <i>CD28</i> among north-Indians, B) LD plot of <i>CD28</i> among CEU population, C) <i>CD28</i> haplotypes among north-Indians, D) <i>CD28</i> haplotypes among CEU population.</p

List of significant (p<0.05) SNPs in and around IL23R gene.

<p>List of significant (p<0.05) SNPs in and around IL23R gene.</p

Significant allelic/genotypic associations [p value; OR (95%CI)] of genes/markers tested in total sample set and <i>prakriti</i>-wise subgroups.

<p>NS = not significant.</p>#<p>was previously referred to as rs6954345.</p><p>‘*’stands significant at FDR <0.05.</p

Regression analysis of covariates showing significance (p<0.2) in different <i>prakriti</i> subgroups.

<p>Significant associations are indicated in bold.</p

Significant haplotypic# associations [p value; OR (95%CI)] of genes/markers tested in total sample set and <i>prakriti</i>-wise subgroups.

#<p>Order of markers constituting the haplotypes are indicated in parentheses after the genes.</p><p>NS = not significant.</p><p>‘*’adjusted p = 0.02.</p><p>‘**’adjusted p = 0.004.</p

<i>Prakriti</i>-wise distribution and demography of the study samples.

<p><i>Prakriti</i>-wise distribution and demography of the study samples.</p

Comparison of clinical parameters between <i>prakriti</i> subgroups.

*<p>Values not available for all the samples in the study, thus there are varying numbers in the group under the different parameters.</p>**<p>‘+’ and ‘−’ indicate higher and lower means of parameter between respective comparison groups; these are shown only for those comparisons showing significant differences.</p><p>Significant associations are indicated in bold.</p