5 research outputs found
Incidence and geographic distribution of extensively drug-resistant tuberculosis in KwaZulu-Natal Province, South Africa
South Africa is experiencing a widespread drug-resistant tuberculosis epidemic, although
data are limited regarding the current situation. This study finds that the extensively drugresistant
tuberculosis (XDR-TB) incidence in KwaZulu-Natal increased to 3.5 cases/
100,000 (776 cases) in 2011-2012. XDR-TB cases are widely distributed geographically,
with the majority of districts experiencing a rise in incidence.This work was supported by: R01
AI089349, National Institutes of Health, NRG NSS
(http://www.nih.gov/); 2007071, Doris Duke Charitable
Foundation Clinical Scientist Development Award,
NSS (http://www.ddcf.org/); 2007070, Doris Duke
Charitable Foundation Clinical Scientist Development
Award, NRG (http://www.ddcf.org/); K24 114444, K24
Career Development Award from the National
Institute of Allergy and Infectious Diseases, NRG
(http://www.niaid.nih.gov/Pages/default.aspx); P30 AI050409, Emory University Center for AIDS
Research, NRG (http://www.cfar.emory.edu/); K23
AI083088, National Institutes of Health, JCMB (http://
www.nih.gov/); and P30 AI051519, Einstein-
Montefiore Center for AIDS Research, JCMB (http://
www.einstein.yu.edu/centers/center-for-aidsresearch/).http://www.plosone.orgam201
Change in incidence of XDR-TB in KwaZulu-Natal province, South Africa, 2007 to 2010–12.
<p>Panel A shows the XDR-TB incidence (per 100,000 population) in each district in 2007. Panel B shows the average XDR-TB incidence by district in 2010–2012. The size of the circles is proportional to the incidence rate. The colors in panel B represents the change in incidence compared to 2007 data: red, increase; green, decrease.</p
Cases of XDR-TB in KwaZulu-Natal province, South Africa, October 2010-December 2012.
<p>*Statistics Soth Africa, 2012. [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132076#pone.0132076.ref014" target="_blank">14</a>]</p><p><sup>†</sup>Moodley et al. PLOS ONE 011. [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132076#pone.0132076.ref006" target="_blank">6</a>]</p><p>Cases of XDR-TB in KwaZulu-Natal province, South Africa, October 2010-December 2012.</p