Gems: Objects of aesthetic beauty and scientific curiosity

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Heats of Formation of Solid Solutions of CsCl with CsBr

1008-100

Is IT enough? Evidence from a natural experiment in India's agriculture markets

Access to information and communication technologies (ICTs) such as mobile phone networks is widely known to improve market efficiency. In this paper, we examine whether access to timely and accurate information provided through ICT applications has any additional impact. Using a detailed data set from Reuters Market Light (RML), a text message service in India that provides daily price information to market participants, we find that this information reduces the geographic price dispersion of crops in rural communities by an average of 12%, over and above access to mobile phone technology and other means of communication. To identify the effect of information on price dispersion, we exploit a natural experiment where bulk text messages were banned unexpectedly across India for 12 days in 2010. We find that besides reducing geographic price dispersion, RML also increases the rate at which prices converge across India over time. We discuss the implications of this for development organizations and information providers

RecA protein promoted homologous pairing in vitro. Pairing between linear duplex DNA bound to HU Protein (nucleosome cores) and nucleoprotein filaments of recA protein-single-stranded DNA

RecA protein promotes two distinct types of synaptic structures between circular single strands and duplex DNA; paranemic joints, where true intertwining of paired strands is prohibited and the classically intertwined plectonemic form of heteroduplex DNA. Paranemic joints are less stable than plectonemic joints and are believed to be the precursors for the formation of plectonemic joints. We present evidence that under strand exchange conditions the binding of HU protein, from Escherichia coli, to duplex DNA differentially affects homologous pairing in vitro. This conclusion is based on the observation that the formation of paranemic joint molecules was not affected, whereas the formation of plectonemic joint molecules was inhibited from the start of the reaction. Furthermore, introduction of HU protein into an ongoing reaction stalls further increase in the rate of the reaction. By contrast, binding of HU protein to circular single strands has neither stimulatory nor inhibitory effect. Since the formation of paranemic joint molecules is believed to generate positive supercoiling in the duplex DNA, we have examined the ability of positive superhelical DNA to serve as a template in the formation of paranemic joint molecules. The inert positively supercoiled DNA could be converted into an active substrate, in situ, by the action of wheat germ topoisomerase I. Taken collectively, these results indicate that the structural features of the bacterial chromosome which include DNA supercoiling and organization of DNA into nucleosome-like structures by HU protein modulate homologous pairing promoted by the nucleoprotein filaments of recA protein single-stranded DNA

Nested conformal prediction and quantile out-of-bag ensemble methods

Conformal prediction is a popular tool for providing valid prediction sets for classification and regression problems, without relying on any distributional assumptions on the data. While the traditional description of conformal prediction starts with a nonconformity score, we provide an alternate (but equivalent) view that starts with a sequence of nested sets and calibrates them to find a valid prediction set. The nested framework subsumes all nonconformity scores, including recent proposals based on quantile regression and density estimation. While these ideas were originally derived based on sample splitting, our framework seamlessly extends them to other aggregation schemes like cross-conformal, jackknife+ and out-of-bag methods. We use the framework to derive a new algorithm (QOOB, pronounced cube) that combines four ideas: quantile regression, cross-conformalization, ensemble methods and out-of-bag predictions. We develop a computationally efficient implementation of cross-conformal, that is also used by QOOB. In a detailed numerical investigation, QOOB performs either the best or close to the best on all simulated and real datasets.Comment: 38 pages, 5 figures, 8 table

Robust scheduling practices in the U.S. airline industry: Costs, returns, and inefficiencies

Airlines use robust scheduling to mitigate the impact of unforeseeable disruptions on profits. We examine how effectively three common practices—flexibility to swap aircraft, flexibility to reassign gates, and scheduled aircraft downtime—accomplish this goal. We first estimate a multiple-input, multiple-outcome production frontier, which defines the attainable set of outcomes from given inputs. We then recover unobserved input costs and calculate how expenditure on inputs affects outcomes and revenues. We find that the per-dollar return from expenditure on gates, or more effective management of existing gate capacity, is three times larger than the per-dollar returns from other inputs. Next, we use the estimated trade-offs faced by carriers along the frontier to measure the value to carriers of reducing delays. Finally, we calculate the improvement in carriers’ outcomes and profits if their operational inefficiencies are eliminated. On average, we estimate that operational inefficiencies cost carriers about $1.7 billion in revenue annually

Central Mucoepidermoid carcinoma of mandible – A case report and review of the literature

BACKGROUND: Primary central mucoepidermoid carcinoma of jaws is a rare lesion comprising 2–3% of all mucoepidermoid carcinomas reported in literature. CASE PRESENTATION: The case presented here illustrates the hypothesis that its specific pathogenesis is unknown. CONCLUSIONS: Mucoepidermoid carcinoma of the jaw is a rare tumour of unknown aetiology. Although about a 100 cases has been reported in literature, the speculation on its aetiopathogenesis has mainly centred on the pluripotential capabilities of the epithelial lining of odontogenic cysts

Some illustrations of the optical behaviour of iridescent calcite

The paper reproduces illustrations of various optical effects displayed by twinning layers in iridescent calcite. Brief descriptive notes are appended

Learning from Many: Partner Exposure and Team Familiarity in Fluid Teams

In services where teams come together for short collaborations, managers are often advised to strive for high team familiarity so as to improve coordination and consequently, performance. However, inducing high team familiarity by keeping team membership intact can limit workers’ opportunities to acquire useful knowledge and alternative practices from exposure to a broader set of partners. We introduce an empirical measure for prior partner exposure and estimate its impact (along with that of team familiarity) on operational performance using data from the London Ambulance Service. Our analysis focuses on ambulance transports involving new paramedic recruits, where exogenous changes in team membership enable identification of the performance effect. Specifically, we investigate the impact of prior partner exposure on time spent during patient pickup at the scene and patient handover at the hospital. We find that the effect varies with the process characteristics. For the patient pickup process, which is less standardized, greater partner exposure directly improves performance. For the more standardized patient handover process, this beneficial effect is triggered beyond a threshold of sufficient individual experience. In addition, we find some evidence that this beneficial performance impact of prior partner exposure is amplified during periods of high workload, particularly for the patient handover process. Finally, a counterfactual analysis based on our estimates shows that a team formation strategy emphasizing partner exposure outperforms one that emphasizes team familiarity by about 9.2% in our empirical context