1 research outputs found
Correlation of Bony Invasion With Nodal Metastasis, Pattern of Invasion and Survival in Oral Squamous Cell Carcinoma: A Retrospective Analysis of 122 Primary Cases From Oral Cancer Centre of South India
Oral squamous cell carcinoma (OSCC) is considered to be the most common epithelial malignant neoplasm
of the oral cavity. Despite advancements in diagnosis and therapeutics the clinical outcome of the disease
has not improved much which may be attributed to tumor biology and heterogeneity. Bone invasion by
cancer cells is currently staged as a moderately advanced disease. However, many low-grade carcinomas
such as verrucous carcinoma and carcinoma cuniculatum show body invasion but less nodal metastases and
better overall survival. The present study was orchestrated to analyze if bone invasion in OSCC has any
impact on regional nodal metastases and survival