667 research outputs found

    On the flints and cherts from the uppermost Cretaceous beds (the Niniyur stage) of the Trichinopoly District-S. India

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    On the age of the Deccan traps near Rajahmundry

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    It must be remembered, however, that practically all this palaeontological evidence in support of an eocene age for the Deccan trap comes from plant fossils; and the question naturally arises as to what dependence is to be placed upon fossil plants as a guide to geological age—how far they could be considered "absolute indicators of a geological horizon". Whenever there has been a possible difference of opinion on the age of a bed as determined by the evidence of terrestrial fossil plants as against fossil marine animals, it is true that the geologist will always prefer the evidence of the latter and fix the age accordingly. But in a case like the age of the inter-traps where the decisive evidence of fossil marine animals is not available, it seems only reasonable to accept an age based on the verdict of the plant fossils, unless such a conclusion can be shown to be definitely unacceptable from the geological side

    A randomized open label parallel group study comparing the safety, effectiveness and adherence between 2% fusidic acid cream versus 1% retapamulin ointment in children with impetigo

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    Background: Impetigo is a contagious bacterial skin infection that affects both adults and children. Topical antibacterials such as mupirocin and fusidic acid are the most commonly used in both primary and secondary impetigo. Clinical trials have shown high efficacy of retapamulin in the treatment of secondary impetigo. However, its use in primary impetigo is limited. To this purpose, we compared the safety, efficacy and adherence to treatment of fusidic acid with retapamulin in primary impetigo.Methods: A total of 50 patients with a clinical diagnosis of primary impetigo, between 2-12 years of age, having 0.05). Both drugs were well tolerated.Conclusions: Both fusidic and retapamulin showed similar clinical success in patients with primary impetigo. Since fusidic acid has anti-inflammatory property and its treatment is cost-effective, it can be considered as first-line treatment and retapamulin in fusidic acid-resistant impetigo

    GM-CSF DNA: An adjuvant for higher avidity IgG, rectal IgA, and increased protection against the acute phase of a SHIV-89.6P challenge by a DNA/MVA immunodeficiency virus vaccine

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    AbstractSingle intradermal or intramuscular inoculations of GM-CSF DNA with the DNA prime for a simian–human immunodeficiency virus (SHIV)-89.6 vaccine, which consists of DNA priming followed by modified vaccinia Ankara (MVA) boosting, increased protection of both the blood and intestines against the acute phase of an intrarectal SHIV-89.6P challenge. GM-CSF appeared to contribute to protection by enhancing two antibody responses: the avidity maturation of anti-Env IgG in blood (p=<0.01) and the presence of long lasting anti-viral IgA in rectal secretions (p<0.01). The avidity of anti-Env IgG showed strong correlations with protection both pre and post challenge. Animals with the highest avidity anti-Env Ab had 1000-fold reductions in peak viremia over those with the lowest avidity anti-Env Ab. The enhanced IgA response was associated with the best protection, but did not achieve significance

    Effect of supplementing encapsulated microbial enzymes to corn-soybean meal based pelleted diets on performance and carcass variables in coloured broiler chicken

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    The experiment was conducted to determine the dietary supplementation of encapsulated (EC) or UEC enzymes on performance of colour broilers. The dietary supplementation of EC polysaccharide hydrolyzing enzymes and protease improved the performance compared to other groups. Feeding the birds with low nutrient-density diets did not affect the performance of the coloured broilers. The supplementation of EC enzymes resulted in a decrease in abdominal fat and increase in ready to cook yield compared to those diets with UEC or without enzymes

    Global bundle adjustment with variable orientation point distance for precise mars express orbit reconstruction

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    The photogrammetric bundle adjustment of line scanner image data requires a precise description of the time-dependent image orientation. For this task exterior orientation parameters of discrete points are used to model position and viewing direction of a camera trajectory via polynomials. This paper investigates the influence of the distance between these orientation points on the quality of trajectory modeling. A new method adapts the distance along the trajectory to the available image information. Compared to a constant distance as used previously, a better reconstruction of the exterior orientation is possible, especially when image quality changes within a strip. In our research we use image strips of the High Resolution Stereo Camera (HRSC), taken to map the Martian surface. Several experiments on the global image data set have been carried out to investigate how the bundle adjustment improves the image orientation, if the new method is employed. For evaluation the forward intersection errors of 3D points derived from HRSC images, as well as their remaining height differences to the MOLA DTM are used. In 13.5 % (515 of 3,828) of the image strips, taken during this ongoing mission over the last 12 years, high frequency image distortions were found. Bundle adjustment with a constant orientation point distance was able to reconstruct the orbit in 239 (46.4 %) cases. A variable orientation point distance increased this number to 507 (98.6 %).German Federal Ministry for Economic Affairs and Energy (BMWi)German Aerospace Center (DLR)/50 QM 130

    Exchange bias effect in alloys and compounds

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    The phenomenology of exchange bias effects observed in structurally single-phase alloys and compounds but composed of a variety of coexisting magnetic phases such as ferromagnetic, antiferromagnetic, ferrimagnetic, spin-glass, cluster-glass and disordered magnetic states are reviewed. The investigations on exchange bias effects are discussed in diverse types of alloys and compounds where qualitative and quantitative aspects of magnetism are focused based on macroscopic experimental tools such as magnetization and magnetoresistance measurements. Here, we focus on improvement of fundamental issues of the exchange bias effects rather than on their technological importance

    SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses

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    Vaccine regimens using different agents for priming and boosting have become popular for enhancing T cell and Ab responses elicited by candidate HIV/AIDS vaccines. Here we use a simian model to evaluate immunogenicity and protective efficacy of a recombinant modified vaccinia Ankara (MVA) vaccine in the presence and absence of a recombinant DNA prime. The simian vaccines and regimens represent prototypes for candidate HIV vaccines currently undergoing clinical testing
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