7 research outputs found

    Tecate, caracterización de atributos turísticos y empresas

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    The Magical Towns Program (MTP) it’s a public policy strategy that has incorporated 132 until the year 2021 and seeks to promote sustainable tourism. Tecate has been part of this public policy since 2012. This exploratory study analyzes the relevance of its incorporation, describes its tourist heritage and its business network based on an on-site investigation, using observation and survey techniques. The data illustrates a magical urban town, with tourist attractions and services, a business sector dedicated mostly to commerce, that are key elements to articulate and generate a competitive tourism product that enhances the current benefits represented in formal employment with an average remuneration of 2.5 minimum wages.El Programa Pueblos Mágicos (PPM) es una estrategia de política pública que ha incorporado a 132 localidades hasta el año 2021 y busca promover el turismo sustentable. Tecate, Baja California, forma parte de este programa público desde 2012. En este estudio exploratorio se analiza la pertinencia de su incorporación, se describe su patrimonio turístico y su tejido empresarial a partir de una investigación in situ, utilizando las técnicas de observación y encuesta. Los datos ilustran un pueblo mágico urbano, con atractivos y servicios turísticos, un tejido empresarial dedicado mayormente al comercio, que son elementos factibles de articularse para generar un producto turístico competitivo que potencie los beneficios actuales representados en empleo formal, con una remuneración promedio de 2,5 salarios mínimos

    Tecate, caracterización de atributos turísticos y empresas

    Get PDF
    El Programa Pueblos Mágicos (PPM) es una estrategia de política pública que ha incorporado a 132 localidades hasta el año 2021 y busca promover el turismo sustentable. Tecate, Baja California, forma parte de este programa público desde 2012. En este estudio exploratorio se analiza la pertinencia de su incorporación, se describe su patrimonio turístico y su tejido empresarial a partir de una investigación in situ, utilizando las técnicas de observación y encuesta. Los datos ilustran un pueblo mágico urbano, con atractivos y servicios turísticos, un tejido empresarial dedicado mayormente al comercio, que son elementos factibles de articularse para generar un producto turístico competitivo que potencie los beneficios actuales representados en empleo formal, con una remuneración promedio de 2,5 salarios mínimos

    Infective Endocarditis in End-Stage Renal Disease Patients in Developing Countries: What is the Real Problem?

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    The epidemiology of infective endocarditis (IE) has changed over the last decades, due to various factors. This chapter focuses on IE in patients with end-stage renal disease. Then it reviews the most relevant reports published in the last decade worldwide; the different scenarios in developing countries versus developed countries; different microorganisms, treatment times, and outcomes; and also our own experience in these patients. Finally, it mentions the recommendations that have helped some developed countries to reduce more than 50% of bacteremia in catheter patients and how to make them possible in developing countries

    A novel approach for direct detection of the IGH::CRLF2 gene fusion by fluorescent in situ hybridization

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    Abstract Background High expression of the Cytokine Receptor-Like Factor 2 (CRLF2) gene has been observed in patients with acute lymphoblastic leukemia BCR-ABL1-like subtype. Currently, there is no commercial system available for the direct detection of the IGH::CRLF2 fusion by fluorescent in situ hybridization (FISH), as there are for many other leukemia-related gene fusions. In an effort to verify the IGH::CRLF2 fusion, some researchers prepare home-grown FISH probes from bacterial artificial chromosome clones flanking the IGH and CRLF2 genes, which is the best alternative to confirm the fusion, however difficult to reproduce in most cytogenetic laboratories. Results For the direct observation of the IGH::CRLF2 gene fusion we designed a methodological approach requiring the two commercially available IGH and CRLF2 break-apart probes. Conclusions Our methodological approach allows direct visualization of the IGH::CRLF2 gene fusion and has the potential to be used for identification of other gene fusions

    High-Intensity Ultrasound Pulses Effect on Physicochemical and Antioxidant Properties of Tilapia (Oreochromis niloticus) Skin Gelatin

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    Ultrasonic pulses are considered green technology for the improvement of the functional properties of proteins. In this study, four high-intensity ultrasound pulse treatments (ultrasound-pulsed gelatin (UPG)-42, UPG-52, UPG-71, UPG-84, and non-pulsed control gelatin (CG)) were applied to tilapia (Oreochromis niloticus) skin gelatin in order to study their effect on its physicochemical and antioxidant properties; a non-treated gelatin was used as a control. UPGs showed a significant increase in soluble protein and surface hydrophobicity compared to the control gelatin, and no significant difference was found in the electrophoretic profiles. The effects on the secondary structure were studied by circular dichroism and infrared spectra, and these showed that the random coil conformation was the main component in all treatments and the ultrasonic treatments only affected the α-helix and β-sheet proportion. Finally, the ABTS ((2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)) and FRAP (ferric reducing ability) assays demonstrated that ultrasound treatments could improve the antioxidant activity of gelatins as free radical scavengers and electron donors. These results suggest that high-intensity ultrasound pulse technology is useful to improve fish gelatin antioxidant properties, which could be associated with secondary structure disruption

    Effect of Different Polyalcohols as Plasticizers on the Functional Properties of Squid Protein Film (<i>Dosidicus Gigas</i>)

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    Conventional plastic materials accumulation has led to a constant search to develop friendly packaging, edible coatings from biopolymers are an example. Since different proteins have different behavior and plastizicer compatibility, in this work, the effect of different polyalcohols (glycerol, sorbitol, maltitol, mannitol, and xylitol) as plasticizers on squid protein films behavior was studied. The results show that except for mannitol, transparent, and flexible films can be obtained. None of them showed transmission to light on the ultraviolet (UV) spectrum. However, only glycerol and sorbitol were sufficiently flexible to evaluate their mechanical properties, in which glycerol had a more elastic behavior with an elongation at a break of 920% and tensile strength (TS) of 0.94 MPa, while sorbitol exhibited a more plastic behavior with an elongation at break of 511% and a TS of 4.41 MPa. Water-vapor transmission rate was higher in glycerol, with 194.41 g&#183;m&#8722;2d&#8722;1, while sorbitol had 44.27 g&#183;m&#8722;2d&#8722;1 but presented blooming. This could be due to low interaction between sorbitol and the protein matrix, correlating with the film-solubility results. Amide I band of the Fourier transform infrared (FT-IR) spectra demonstrated higher denaturation and loss of alpha helical structure in glycerol film, followed by maltitol/sorbitol, xylitol, mannitol, and the control film. This in accordance with thermogravimetric analysis (TGA) results. The results of this study prove that only glycerol and sorbitol are suitable to obtain a see-through flexible film
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