Evidence (edge) strength between network protein pairs shown in Figure 5 (more links/edges between two nodes typically would mean more support in the literature).

<p>Only links associated with hub-node proteins (refer <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034480#pone-0034480-t004" target="_blank">Table 4</a>) are shown.</p

Hub nodes in PIN generated by CPNM for Case Study II.

<p>Hub nodes in PIN generated by CPNM for Case Study II.</p

Outbound, inbound, and undirected edge connectivity for a node.

<p>This table shows the distribution of direction information for a given protein in the network diagram shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034480#pone-0034480-g005" target="_blank">Figure 5</a>. Only links associated with hub-node proteins (refer <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034480#pone-0034480-t004" target="_blank">Table 4</a>) are shown.</p

CPNM output showing protein interactions extracted from literature for Case Study I.

<p>CPNM output showing protein interactions extracted from literature for Case Study I.</p

PIN generated by CPNM for Case Study I.

<p>PIN generated by CPNM for Case Study I.</p

Sample query formulation by CPNM.

<p>Sample query formulation by CPNM.</p

List of differentially expressed genes with fold change >3 selected for Case Study II.

<p>List of differentially expressed genes with fold change >3 selected for Case Study II.</p

CPNM web interface with query builder.

<p>CPNM web interface with query builder.</p

PIN generated by CPNM for Case Study II.

<p>PIN generated by CPNM for Case Study II.</p

Accuracy of CPNM on PI triplet prediction task based on 10-fold cross validation on a gold-standard dataset.

<p>Accuracy of CPNM on PI triplet prediction task based on 10-fold cross validation on a gold-standard dataset.</p