Increasing the productivity of rajma through proper sowing date and plant geometry

Rajma (Phaseolus vulgaris L.) cultivation is gaining popularity in Terai to Hills of Nepal. The poor plant establishment and yield due to the results of unsuitable sowing time and row spacing are the main reasons for lower productivity of it. Therefore, the date of sowing and row spacing trials were conducted in two consecutive years, 2017 and 2018 at the Grain Legumes Research Program, Khajura, Banke. A widespread and registered variety of rajma PDR 14 was used in the experiment. The experiment was laid out in a split-plot design with four sowing dates (a) 11th October, (b) 26th October, (c) 10th November and (d) 25th November as the main-factor, and three rows spacing (a) 30 cm, (b) 40 cm and (c) 50 cm as the sub-factor, consisted of three replications. The effect of the date of sowing on all the yield and yield attributing characters was found significant at a one percent significance level. Similarly, row spacing has resulted in a significant difference in grain yield. Rajma sown on 26th October (Kartik 9) produced 12, 38 and 64% higher grain yield than sown on 11th October, 10th November and 25th November, respectively. Moreover, rajma seeds sown on 26th October with 30 cm × 10 cm plant geometry produced the highest grain yield (2185 kg/ha). The narrow row spacing seemed well than the wider row in rajma production. There is a great potential to increase the production and productivity of rajma through an appropriate time of sowing and row spacing

Abnormalities in structural covariance of cortical gyrification in schizophrenia

The highly convoluted shape of the adult human brain results from several well-coordinated maturational events that start from embryonic development and extend through the adult life span. Disturbances in these maturational events can result in various neurological and psychiatric disorders, resulting in abnormal patterns of morphological relationship among cortical structures (structural covariance). Structural covariance can be studied using graph theory-based approaches that evaluate topological properties of brain networks. Covariance-based graph metrics allow cross-sectional study of coordinated maturational relationship among brain regions. Disrupted gyrification of focal brain regions is a consistent feature of schizophrenia. However, it is unclear if these localized disturbances result from a failure of coordinated development of brain regions in schizophrenia. We studied the structural covariance of gyrification in a sample of 41 patients with schizophrenia and 40 healthy controls by constructing gyrification-based networks using a 3-dimensional index. We found that several key regions including anterior insula and dorsolateral prefrontal cortex show increased segregation in schizophrenia, alongside reduced segregation in somato-sensory and occipital regions. Patients also showed a lack of prominence of the distributed covariance (hubness) of cingulate cortex. The abnormal segregated folding pattern in the right peri-sylvian regions (insula and fronto-temporal cortex) was associated with greater severity of illness. The study of structural covariance in cortical folding supports the presence of subtle deviation in the coordinated development of cortical convolutions in schizophrenia. The heterogeneity in the severity of schizophrenia could be explained in part by aberrant trajectories of neurodevelopment

The prevention of‑ and first response to‑ injuries in Nepal: A review of policies and legislation

Background: Injuries, the cause of an estimated 4.5 million deaths annually and many more disabilities worldwide each year, are the predictable outcome of particular circumstances. One of the most effective ways to prevent injuries is through policy and legislation. The aim of this research study was to identify and critically review all policy and legislation in Nepal that had the potential to prevent injuries. Methods: We identified legislation and policy that met inclusion criteria through a stakeholder meeting, networks and contacts, and websites and electronic resources. Each included document was critically reviewed to identify areas of strength and opportunities for improvement. We compared the included documents against WHO’s recommendations of known effective interventions. Results: Sixty-two documents met the inclusion criteria for this review. Of these, 24 (38.7%) were exclusively related to road injuries, 11 (17.7%) to occupational injuries, 6 (9.7%) to injuries in the home and 5 (8.1%) to injuries at school; 30 (48.4%) documents included text related to the first response to injuries. Of 127 strategic recommendations by WHO that provided an area for policy or legislative focus, 21 (16.5%) were considered adequately met by Nepali policy and legislation, 43 (33.9%) were considered partially met and 63 (49.6%) were not met. Conclusion: We drew five conclusions from this critical policy review, which we have related to recommendations as follows: widening the scope of legislation and policy for injury prevention to emphasize injuries occurring at home or school; addressing the causes of injuries and promoting proven preventive measures; greater clarity on both individual and institutional roles and responsibilities; trustworthy data and quality evidence to inform decision-making; and financial investment and capacity-strengthening for injury prevention and first response. The current system of federal governance in Nepal has potential for strengthening injury prevention and first response at the central, provincial and local levels

Sol-gel synthesis, characterization of ZnO thin films on different substrates, and bandgap calculation by the Tauc plot method

The sol-gel spin coating method was used for the preparation of the Zinc Oxide which was coated over polymer, transparent, and glass translucent substrates and characterized with the help of a UV-Vis Spectroscope. The wavelength bandgap of those samples was found to be 296nm, 310.5nm, and 330nm respectively. The actual band gap of ZnO is 388nm. Similarly, their optical bandgap energy calculated by the Tauc Plot method were 3.641eV, 3.385eV, and 3.495 eV respectively. The transparent polymer slide has the lowest wavelength bandgap and the translucent glass slide has the highest. Further, the bandgap’s value differs from its actual value to the difference in the absorption process due to the presence of the substrate. These results suggest that the choice of substrate can significantly impact the optical properties and performance of the zinc oxide thin film. This result can be applied in developing and optimizing zinc oxide thin films for various purposes, such as in solar cells, sensors, and optoelectronics. By carefully selecting the substrate, it may be possible to tailor the bandgap energy and other optical properties of the thin film to better suit the specific application

Sol-gel synthesis, characterization of ZnO thin films on different substrates, and bandgap calculation by the Tauc plot method

The sol-gel spin coating method was used for the preparation of the Zinc Oxide which was coated over polymer, transparent, and glass translucent substrates and characterized with the help of a UV-Vis Spectroscope. The wavelength bandgap of those samples was found to be 296nm, 310.5nm, and 330nm respectively. The actual band gap of ZnO is 388nm. Similarly, their optical bandgap energy calculated by the Tauc Plot method were 3.641eV, 3.385eV, and 3.495 eV respectively. The transparent polymer slide has the lowest wavelength bandgap and the translucent glass slide has the highest. Further, the bandgap’s value differs from its actual value to the difference in the absorption process due to the presence of the substrate. These results suggest that the choice of substrate can significantly impact the optical properties and performance of the zinc oxide thin film. This result can be applied in developing and optimizing zinc oxide thin films for various purposes, such as in solar cells, sensors, and optoelectronics. By carefully selecting the substrate, it may be possible to tailor the bandgap energy and other optical properties of the thin film to better suit the specific application

Phenotypic characterization of wheat landraces from mid and far western districts of Nepal

The study was conducted to evaluate phenotypic variation in one hundred and sixty six wheat landraces from mid and far western districts of Nepal. They were sown in randomized complete block design with two replications at National Wheat Research Program in 2014/15. The observed traits were analyzed using descriptive statistics and multivariate analysis using MINITAB v. 14. The results showed a wide range of phenotypic variability in observed parameters. The results also showed that the highest value of the standard deviation from mean (Sd) was for grain yield (±290.10) followed by plant height (±7.21). Among the traits the lowest deviation from mean (Sd) was for thousand grain weight TGW (±2.68). Wheat landraces grouped in four clusters depending on similarity of the studied traits. The results in this cluster, showed that days to maturity ranged from 97 to111 days, TGW ranged from 16 to17 gm, plant height ranged from 76 to 85 cm, and grain yield ranged from 2800 to 3000 Kg ha-1. Wheat landraces under study are grouped depending on specific traits useful for wheat improvement program. Results of this study can be supportive to detect wheat landraces within species with similar traits. In addition it can be useful for sampling in successive studies and parental selection in wheat breeding program.International Journal of Environment Vol.4(4) 2015: 32-44</p

Wheat Variety Improvement for Climate Resilience

High temperature stress unfavorably affects plant growth and reduces grain yield (GY). This study was conducted with an aim to identify the terminal heat tolerance of one hundred and two wheat genotypes with three checks. They were sown under normal (non-stress) and late (stress) conditions at Regional Agricultural Research Station (RARS), Tarahara; RARS, Nepalgunj and National Wheat Research Program (NWRP), Bhairahawa, Nepal. The trial was sown in Augmented design during 2014/15 winter season as a Nepal heat tolerance wheat screening nursery (NHTWSN). Grain yield, maturity, stress susceptibility and tolerant indices were estimated to assess the heat tolerance of the genotypes. Combined analysis among the tested wheat lines (102 new entries + 3 checks) showed that KACHU//KIRITATI/WBLL1 ((Heat tolerance index (HTI) = 1.78) possessed the highest level of heat tolerance, followed by SLVS&nbsp; /3/ CROC_1/ AE.SQUARROSA (224)// OPATA/5/ VEE/LIRA//BOW/3/BCN/4/KAUZ/6/ 2*KA/NAC//TRCH (HTI=1.57) while SUP152/VILLA JUAREZ F2009 (HTI=0.83) appeared to be the least heat tolerant. Correlation analysis showed that yield under stress environment had positive (r=0.083) and significant (p&lt;0.05) association with that of non-stress environment. Grain yield (Kg/ha) under both environments had significant positive correlation with mean productivity (MP), geometric mean productivity (GMP) and HTI. Thirty seven wheat genotypes possessing heat tolerance will be considered in further heat tolerance trial and can also be used directly in varietal development and in the crossing program to breed more heat tolerant genotypes

Use of Antidepressants among Patients Diagnosed with Depression: A Scoping Review

Introduction. Depression is a major global health problem with a relatively high lifetime prevalence and significant disability. Antidepressants are the most effective medications used for the treatment of depression. Hence, this study is aimed at summarizing the studies on antidepressant use among patients diagnosed with depression. Method. PubMed, Embase, Web of Science, Scopus, and Google Scholar were searched for literature (2000-2019) using keywords such as depression, drug utilization, antidepressants, prescription, serotonin reuptake inhibitor, serotonin and norepinephrine reuptake inhibitor, tricyclic antidepressants, and atypical antidepressants. Results. Antidepressant users were mostly females, married people, housewives, lower-income people, employees, and highly educated people, as they were found to be more prone to develop depression than their counterparts. Selective serotonin reuptake inhibitors (SSRIs), such as sertraline, were most commonly prescribed among depressive patients. Conclusion. Our study suggested that out of five major antidepressant drugs available for the treatment of depression, selective serotonin reuptake inhibitors are preferred over others because of their better side effects and tolerability profile