Tamo gdje završava drama mentaliteta započinje drama političkog trenutka. Ivan Vidić, Octopussy, HNK, Zagreb & Veliki bijeli zec, ZeKaeM

<p><b>Copyright information:</b></p><p>Taken from "Host-pathogen systems biology: logical modelling of hepatocyte growth factor and induced c-Met signal transduction"</p><p>http://www.biomedcentral.com/1752-0509/2/4</p><p>BMC Systems Biology 2008;2():4-4.</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2254585.</p><p></p

The three identified clusters and their annotations.

<p>The three identified clusters and their annotations.</p

Differentially Expressed Genes Between the Different Clusters.

<p>These genes are found to be differentially expressed in most of the normalisation methods and irrespective of the level of filtering.</p

Cluster dendrogram from hierarchical agglomerative clustering of the gcrma normalised data, filtered with interquartile range filtering to give 282 probesets.

<p>Cluster dendrogram from hierarchical agglomerative clustering of the gcrma normalised data, filtered with interquartile range filtering to give 282 probesets.</p

Boxplots of the log2 transformed data normalised using A) rma, B) gcrma, and C) farms.

<p>Boxplots of the log2 transformed data normalised using A) rma, B) gcrma, and C) farms.</p

Cluster Assignments and the Consensus From Analysis of the Dendrograms Produced by Agglomerative Hierarchical Clustersing of the Normalised and Filtered Datasets.

<p>The two filtering methods are that according to Golub or using the Interquartile Range <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050253#pone.0050253-Golub1" target="_blank">[21]</a>. The normalisation methods are farms, rma or gcrma. The probeset sizes are approximately 1000 (L) or approximately 300 (S). The arrays are assigned to clusters 1,2,3 or 0 means there is no consensus and gaps indicate not cluster was assigned from that dendrogram.</p

Heatmap for the differentially expressed genes between clusters 1 and 2 for the rma normalised data filtered using the IQR method to give 1025 probes.

<p>Heatmap for the differentially expressed genes between clusters 1 and 2 for the rma normalised data filtered using the IQR method to give 1025 probes.</p

Values for the Filtering of the Microarray Probeset Level Data.

<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050253#pone-0050253-t001" target="_blank">Table 1A</a> are the parameters for the Golub filtering and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050253#pone-0050253-t001" target="_blank">Table 1B</a> are the parameters for the median based fitting. Where <b>r</b> is the ratio between the highest and lowest level of expression for a particular probe across all the arrays and <b>d</b> is the difference between the maximum and minimum expression levels. IQR is the interquartile range and the lower threshold must be passed by at least 25% of the arrays.</p

Host-pathogen systems biology: logical modelling of hepatocyte growth factor and induced c-Met signal transduction-7

<p><b>Copyright information:</b></p><p>Taken from "Host-pathogen systems biology: logical modelling of hepatocyte growth factor and induced c-Met signal transduction"</p><p>http://www.biomedcentral.com/1752-0509/2/4</p><p>BMC Systems Biology 2008;2():4-4.</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2254585.</p><p></p

Host-pathogen systems biology: logical modelling of hepatocyte growth factor and induced c-Met signal transduction-3

<p><b>Copyright information:</b></p><p>Taken from "Host-pathogen systems biology: logical modelling of hepatocyte growth factor and induced c-Met signal transduction"</p><p>http://www.biomedcentral.com/1752-0509/2/4</p><p>BMC Systems Biology 2008;2():4-4.</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2254585.</p><p></p