Knowledge and practice of self home monitoring of blood glucose

Objectives: Both glycosylated haemoglobin and self-monitoring of blood glucose (SMBG) are necessary for optimal monitoring of glycaemic control in patients with diabetes mellitus. Methods: A cross-sectional survey was conducted among patients attending the endocrine clinic of Ekiti State University Teaching Hospital, Ado-Ekiti. With the aid of interviewer administered questionnaire, demographic and other information on awareness of SMBG, ownership of glucometer, and practice of SMBG were obtained. The data was analysed with Statistical Package for Social Sciences (SPSS) version 16. Results: One hundred and four patients comprising 29 males (27.9%) and 75 females (72.1%) were studied with a mean age of 59.6±13.7 years. Twenty two (21.2%) subjects had no formal education, while 38 (36.5%), 16 (15.4%), 28(26.9%) subjects had primary, secondary and tertiary education respectively. Sixty seven patients (64.4%) were aware of SMBG. Out of these, only 19 subjects (18.3%) had glucometers. Age and level of education were significantly related to ownership of glucometer (

Communicating carbon removal

Removing carbon dioxide from the atmosphere is “unavoidable” if net zero emissions are to be achieved, and is fast rising up the climate policy agenda. Research, development, demonstration, and deployment of various methods has begun, but technical advances alone will not guarantee a role for them in tackling climate change. For those engrossed in carbon removal debates, it is easy to forget that most people have never heard of these strategies. Public perception of carbon removal is therefore particularly sensitive to framings—the ways in which scientists, entrepreneurs, activists, politicians, the media, and others choose to organize and communicate it. In this perspective, we highlight four aspects of carbon removal for which their framing will play a decisive role in whether—and how—different methods are taken forward. First, the use of analogies can be helpful in guiding mental models, but can also inadvertently imply processes or outcomes that do not apply in the new example. Second, a taxonomic split between “nature-based” and “technological” methods threatens to divert attention from the actual qualities of different methods and constrain our policy options. Third, people are likely to overestimate the emissions-reduction potential of carbon removal, but this misperception can be corrected. Fourth, communications overlook the social arrangements for carbon removal and the alternative trajectories that implementation may take. We end by offering key recommendations for how we can communicate carbon removal more responsibly

Industry‐Dominated Science Advisory Boards Are Perceived To Be Legitimate…But Only When They Recommend More Stringent Risk Management Policies

In 2017, the US Environmental Protection Agency (EPA) was criticized for two controversial directives that restricted the eligibility of academic scientists to serve on the agency’s key science advisory boards (SABs). The EPA portrayed these directives as necessary to ensure the integrity of the SAB. Critics portrayed them as a tactic by the agency to advance a more industry‐friendly deregulatory agenda. With this backdrop, this research examined board composition and its effect on the perceived legitimacy of risk management recommendations by the SAB. In an experiment, we presented participants with hypothetical EPA SABs composed of different proportions of academic and industry scientists. We then asked participants to rate their satisfaction with, and the legitimacy of, these boards in light of their decisions in scenarios based on actual EPA SAB deliberations. Participants perceived higher levels of satisfaction and legitimacy when SABs made more stringent risk management recommendations. While SABs dominated by industry scientists were perceived to be more strongly motivated to protect business interests, we found no effect of board composition on perceptions of satisfaction and legitimacy. These results are consistent with prior research on decision quality that suggests people use normative outcomes as a heuristic for assessing the quality of deliberations. Moreover, these results suggest that members of the public are supportive of federal SABs regardless of their composition, but only if they take actions that are consistent with normative expectations.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163630/2/risa13540.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163630/1/risa13540_am.pd

Endocrine Admissions in a Tertiary Hospital In Nigeria: A 5-Year Review of Pattern and Trend

Hospital admission is a reflection of prevailing disease pattern in an environment, impact of services rendered in the outpatient department and preventative healthcare services in the community. The aim of this study was to determine the pattern and trend of endocrine related admissions at Ekiti State University Teaching Hospital, Ado-Ekiti. This was a retrospective analysis of health records of patients with endocrine related disorders admitted into the medical wards of the hospital between 2008-2012. The diagnoses, based on WHO ICD-10 were documented. Endocrine related admissions were subdivided into diabetes related, thyroid related and non-diabetes hypoglycaemia. Data of interest were compared with Pearson’s Chi-Square and Student’s t test. There were 3818 admissions out of which 457 (12.0%) were endocrine related. Majority of the endocrine admission were DM related (93.9%), representing 11.8% of the total admissions. There was increase in endocrine-related admissions from 9.1%-18.0% and a 10.6% increase in the DM related admissions from 2008 to 2012, but a decline in absolute number of endocrine admissions notably among females (X2 = 39.88, p<0.001). Poor glucose control (42.8%) was the commonest reason for diabetic admission, followed by hyperglycaemic emergencies (31.1%), diabetic foot disease (15.9%), sepsis (2.6%), stroke (2.3%), nephropathy/renal failure (1.6%), diabetic hand (0.9%), hypoglycaemia (0.9%), heart failure (0.7%). Between 2010-2012, hyperglycaemic crisis emerged as the commonest reason for diabetic admission, but overall, there was significant reduction in the number of hospitalizations for all diabetic complications (X2 = 128.69, df= 36, p=0.000). More resources need to be allocated for the management of diabetes mellitus while efforts to prevent its complications through educational activities and public awareness should be sustained

Effect of Al and Mg Doping on Optical Properties of ZnO Thin Films Prepared by Spin Coating

This paper investigated the influence of aluminum and magnesium doping on the optical and electrical properties of zinc oxide (ZnO) thin films for solar cell application. zinc acetate dehydrates was used as starting material. Aluminum chloride and tin chloride were added to each solution to serve as dopants. X-ray diffractions were analyzed by X-ray diffraction (XRD) which revealed crystalline and hexagonal wurtzite structure. All the films showed more than 80% transparency in the visible region. The optical band gap of undoped znO thin film was found to be 3.12ev while that of Al-doped and Mg-doped znO film was estimated to be 3.16eV and 3.26eV respectively. The resistivity of the films measured were 2.51×10–4Ω cm for Al-doped, 2.53×10–4Ω cm for mg-doped and 2.61×10-4Ω cm for undoped znO respectively. The quality of the films deposited in this work is a promising window layer component of a solar cell. The variation in the band gap observed in this work could be explained by Burstein–Moss effect which was fully explained in the discussion section of this work

Dual functionality of <i>O</i>-GlcNAc transferase is required for <i>Drosophila </i>development

Post-translational modification of intracellular proteins with O-linked N-acetylglucosamine (O-GlcNAc) catalysed by O-GlcNAc transferase (OGT) has been linked to regulation of diverse cellular functions. OGT possesses a C-terminal glycosyltransferase catalytic domain and N-terminal tetratricopeptide repeats that are implicated in protein–protein interactions. Drosophila OGT (DmOGT) is encoded by super sex combs (sxc), mutants of which are pupal lethal. However, it is not clear if this phenotype is caused by reduction of O-GlcNAcylation. Here we use a genetic approach to demonstrate that post-pupal Drosophila development can proceed with negligible OGT catalysis, while early embryonic development is OGT activity-dependent. Structural and enzymatic comparison between human OGT (hOGT) and DmOGT informed the rational design of DmOGT point mutants with a range of reduced catalytic activities. Strikingly, a severely hypomorphic OGT mutant complements sxc pupal lethality. However, the hypomorphic OGT mutant-rescued progeny do not produce F2 adults, because a set of Hox genes is de-repressed in F2 embryos, resulting in homeotic phenotypes. Thus, OGT catalytic activity is required up to late pupal stages, while further development proceeds with severely reduced OGT activity

Entrepreneurship for Sustainable Economic Growth in Nigeria

This paper underscores the importance of entrepreneurship as a realistic mechanism for sustainable economic growth in Nigeria considering the experiences of developed nations like the United States and vibrant economies like China and India. The paper discusses that entrepreneurship has been instrumental in economic growth, balanced regional development and job creation in most dynamic economies, where technology is changing at a faster rate and the product lifetime cycle is shrinking. The methodology adopted in this paper is the narrative-textual case study (NTCS); it is a social science research method that relies on the information and data from several sources for problem-solving or problem-identification. The paper reveals that the right business environment for entrepreneurship is lacking in Nigeria on account of the challenges of frequent power outages, bad roads, multiple taxes extortion of money from SMEs by government officials, lack of genuine support service for SMEs and expensive transportation/telecommunications costs have all combined to inhibit entrepreneurship and economic growth. The paper therefore concludes that government should focus on capacity building, improving infrastructure, judicious utilisation of the oil wealth and enabling environment thereby leading to sustainable economic growth

Effect of dung and dung beetle application on topsoil fungal assemblage of a post-coal mining reclamation land : towards soil health improvement

DATA AVAILABILITY STATEMENT: Paired-end sequence reads from this study are available in the Sequence Read Archives of the National Centre for Biotechnological Information under the accession number PRJNA684427 (http://www. ncbi.nlm.nih.gov/bioproject/684427).Please read abstract in article.The Coaltech Research Association NPC and grants from the National Research Foundation of South Africa.http://www.elsevier.com/locate/apsoilZoology and Entomolog