5 research outputs found

    Model diagram. Individuals in the simulated population are assigned demographic characteristics based on the joint probabilities of being in each age, sex, location, and income group given population demographic estimates for India.

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    <p>They are then assigned a probability of having diabetes, either diagnosed or undiagnosed, and having various associated co-morbid risk factors, based on the joint probabilities of these prevalence rates and factors listed in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.s004" target="_blank">S2 Table</a> and illustrated in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.s001" target="_blank">S1 Fig</a> based on prior population estimates for India. Individuals are then subject to the screening instruments listed in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.t001" target="_blank">Table 1</a>, from which the model estimates positive and negative test results and subsequent diabetes complications with and without treatment.</p

    Alternative risk factors included in survey-based screening instruments proposed for detecting undiagnosed diabetes in India [6–8].

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    <p>The model subjects each simulated individual to each of the listed screening instruments to identify how many people would test positive or negative by each instrument.</p><p>Alternative risk factors included in survey-based screening instruments proposed for detecting undiagnosed diabetes in India [<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.ref006" target="_blank">6</a>–<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.ref008" target="_blank">8</a>].</p

    Comparison of instrument performance in published sub-national populations versus synthetic national population [6–8,15].

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    <p>95% credible intervals are shown in parentheses. In all cases, the screening instrument is the first-stage test, and individuals testing positive are then subject to fasting blood glucose testing for diagnostic confirmation.</p><p>Comparison of instrument performance in published sub-national populations versus synthetic national population [<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.ref006" target="_blank">6</a>–<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.ref008" target="_blank">8</a>,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001827#pmed.1001827.ref015" target="_blank">15</a>].</p
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