PASS pharmacological activity prediction of experimental compounds.

PASS pharmacological activity prediction of experimental compounds.</p

GC-MS study of phytochemical components in methanol extract of green jackfruit flour.

(DOCX)</p

Virtual screening results selected phytocompounds of JME docked with the human MAPK3.

Virtual screening results selected phytocompounds of JME docked with the human MAPK3.</p

Pharmacokinetic mapping of experimental compounds.

A) caffeic acid, B) DBDEA, C) syringic acid, and D) metformin.</p

Graphical representation of binding free energies of protein-ligand complexes.

Graphical representation of binding free energies of protein-ligand complexes.</p

Screening of active compounds using ADMET criteria.

Screening of active compounds using ADMET criteria.</p

Fig 9 -

Arrangement (A2) and binding pattern (B2) of binding interactions of DBDEA from JME with the residues of human MAPK3 protein.</p

Binding free energy values of JME phytocompounds and metformin complexed with human MAPK3 protein.

Binding free energy values of JME phytocompounds and metformin complexed with human MAPK3 protein.</p

Fig 11 -

Arrangement (A4) and binding pattern (B4) of binding interactions of metformin from JME with the residues of human MAPK3 protein.</p

Binding interactions of compound 6b and acarbose with α-glucosidase along with their bond length (Å).

Binding interactions of compound 6b and acarbose with α-glucosidase along with their bond length (Å).</p