C-reactive protein: An inflammatory biomarker in oral cancer

C-reactive protein (CRP) is a plasma phase protein that takes part in systemic responses to inflammatory reactions. Its serum concentration can increase up to 1000 folds or more in relation to acute stimuli due to infections, tissue injuries, and malignant disorders. It is highly resistant to proteolysis, principally synthesized in the liver in response to proinflammatory cytokines, i.e. interleukin (IL)-6, IL-1β, and tumor necrosis factor. These cytokines are seen to be related to neoplastic disorders. It forms an integral component of innate immunity and serves primarily to recognize potential pathogens and damaged cells. The present article summarizes the importance of CRP and its significance in oral cancer and associated disorders. It was found that a lowered CRP level may prove to be beneficial in prevention and treatment of oral cavity cancer

Rare case of palatal schwannoma: Case report and review of literature

Schwannomas, also known as neurilemmoma, are benign, slow-growing nerve sheath tumors arising from Schwann cells. Approximately 25-40% of schwannomas occur in the head and neck region. However, schwannomas that present in the oral cavity are relatively rare, constituting around 1% of all described cases in the head and neck region. [1],[2] Here, we report a rare case of an intraoral schwannoma, in a 28-year-old male, with painless swelling located in the posterolateral aspect of the soft palate on the right side. Definitive diagnosis was obtained after histopathology examination. Surgical excision of the tumor was done with no complications or recurrences

Keratocystic odontogenic tumor involving the maxillary antrum with displacement of the third molar: A rare case report

Keratocystic odontogenic tumor (KCOT) is a benign intraosseous neoplasm of the jaw with a high rate of recurrence. The lesion commonly occurs in the mandibular molar-ramus area and is rarely seen in the maxilla. Its occurrence in the maxillary sinus along with a displaced third molar is very rare. This article reports a case of KCOT in a 15-year-old boy with a displaced third molar involving the right maxillary antrum

Adenoid cystic carcinoma of the palate: case report and review of literature

Adenoid Cystic Carcinoma (ACC) is a rare tumor constitutes for less than 1% of head and neck malignancies and 10% of all salivary gland tumors. Palate is the most common site to be involved in the oral cavity followed by parotid gland and submandibular gland. They are usually asymptomatic, slow growing, characteristically shows infiltrative growth and perineural invasion. This paper reports a case of Adenoid Cystic Carcinoma in a 35 year old female man reported with a swelling on the left side of palate involving the hard and soft palate since 8 months which was diagnosed histopathologically and review of literature of the peculiar clinical, and histopathological features.Pan African Medical Journal 2016; 2