Needle(s) in the Haystack – Synchronous Multifocal Tumor Induced Osteomalacia

This is the author accepted manuscript. The final version is available from Endocrine Society via http://dx.doi.org/10.1210/jc.2015-3854MG is supported by the NIHR Cambridge Biomedical Research Centre

Comparing the thermal performance of traditional and modern building in the coastal region of Nagappattinam, Tamil Nadu

542-547<span style="font-size:11.0pt;font-family: " times="" new="" roman";mso-fareast-font-family:advtimes;mso-bidi-font-family:mangal;="" mso-ansi-language:en-gb;mso-fareast-language:en-us;mso-bidi-language:hi"="" lang="EN-GB">Climate has a major effect on the performance of the building and its energy consumption. The traditional houses in the coastal region of Nagapattinam, Tamil Nadu in India located in a warm humid zone represent a unique phenomenon with unique device capable to meet the comfort demand through environmental well adapted design. The traditional house and modern house in the coastal region of Nagappattinam are examined by comparing the thermal performance within the same outdoor condition and the climatic region of Nagappattinam. In this paper, a simplified thermal comparison of a traditional house with a contemporary house have been given by using only data derived from the measurements <span style="font-size:11.0pt; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-bidi-font-family:mangal;mso-ansi-language:en-gb;mso-fareast-language:en-us;="" mso-bidi-language:hi"="" lang="EN-GB">This paper represents that the traditional houses in the coastal region of Nagappattinam provided useful indicators of appropriate architectural design response for future modern buildings.</span

Simulation of the Energy Performance of a Building with Green Roofs and Green Walls in a Tropical Climate

Global temperatures have continued to rise for decades, partly due to human-caused greenhouse gas emissions and subsequent urban heat island (UHI) effects. This current research examines the benefits of urban greenery by studying the impact of green roofs and walls of a building on thermal behavior and heat transfer in a warm and humid climate. This simulation study discusses the importance of greening systems in improving thermal comfort and minimizing the causes of UHI by assessing an integrated green building design. Using the simulation software DesignBuilder, the significance of greening systems, green roofs, and walls in enhancing thermal comfort and reducing the factors that contribute to UHI is investigated. The simulation results are based on the building’s energy usage in hot and humid regions while featuring green roofs and walls. The simulation results indicate a considerable positive impact of greening systems in improving the urban environment in hot and humid tropical climates. Air temperature, radiant temperature, humidity, and solar gain are decreased by urban greening. The total energy consumption and district cooling demand of buildings with green roofs and walls are reduced by 10.5% and 13%, respectively. The greening systems substantially improve air quality and building’s energy efficiency. Thus, the present study‘s findings can benefit urban designers and dwellers in devising strategies for establishing green spaces in congested urban environments by integrating green technologies and systems into built environments

Replacement

The fishmeal replaced with Spirulina platensis, Chlorella vulgaris and Azolla pinnata and the formulated diet fed to Macrobrachium rosenbergii postlarvae to assess the enhancement ability of non-enzymatic antioxidants (vitamin C and E), enzymatic antioxidants (superoxide dismutase (SOD) and catalase (CAT)) and lipid peroxidation (LPx) were analysed. In the present study, the S. platensis, C. vulgaris and A. pinnata inclusion diet fed groups had significant (P < 0.05) improvement in the levels of vitamins C and E in the hepatopancreas and muscle tissue. Among all the diets, the replacement materials in 50% incorporated feed fed groups showed better performance when compared with the control group in non-enzymatic antioxidant activity. The 50% fishmeal replacement (best performance) diet fed groups taken for enzymatic antioxidant study, in SOD, CAT and LPx showed no significant increases when compared with the control group. Hence, the present results revealed that the formulated feed enhanced the vitamins C and E, the result of decreased level of enzymatic antioxidants (SOD, CAT and LPx) revealed that these feeds are non-toxic and do not produce any stress to postlarvae. These ingredients can be used as an alternative protein source for sustainable Macrobrachium culture

Effect of Lactobacillus sporogenes on survival, growth, biochemical constituents and energy utilization of freshwater prawn Macrobrachium rosenbergii post larvae

The present study was conducted to investigate the optimization of probiotic, Lactobacillus sporogenes on survival, growth, biochemical constituents and energy utilization of the freshwater prawn Macrobrachium rosenbergii post larvae (PL). Experimental diets were the same in all, except for the variation in probiotic levels. The probiotic L. sporogenes was used at 0%, 1%, 2%, 3% and 4% inclusion in the experimental diets. These diets were fed to M. rosenbergii PL for a period of 90 days. The food index parameters, such as SR, WG, SGR, FCE and PER were significantly (P < 0.05) higher in 4% L. sporogenes incorporated diet fed PL, whereas the FCR was significantly (P < 0.05) lower in 4% L. sporogenes incorporated diet fed PL. This indicates the fact that this feed produced higher growth rate than that of other experimental diets. Similarly the proximate composition of the total protein, total free amino acid, total carbohydrate, and total lipid content was significantly (P < 0.05) higher in 4% L. sporogenes incorporated diet fed PL. However, insignificant differences were recorded in ash and moisture contents between control and experimental groups. Energy utilization parameters, such as feeding rate, absorption rate, conversion rate and excretory rate were significantly (P < 0.05) higher in 4% L. sporogenes incorporated diet fed PL. Statistically insignificant differences were recorded in metabolic rate between control and experimental groups. This indicates that there were no differences in energy loss between control and experimental groups. However, L. sporogenes incorporated diet fed PL produced better growth performance

Daylight performance analysis of a residential building in a tropical climate

The present study investigates the effects of visible light transmittance in glazing and window-to-wall ratios on the ground floor daylighting performance in a two-storey residential building in a warm-humid climate. The metrics used to optimize daylighting performance with minimal glare are useful daylight illuminance, annual sunlight exposure, and spatial daylight autonomy. The daylighting performance of a residential building is assessed by empirical method and Design-Builder simulation, focusing on overcast sky situations. The useful daylight illuminance is the primary metric for analysing the amount of daylight throughout the year. Annual sunlight exposure and spatial daylight autonomy complement useful daylight illuminance in evaluating the daylighting performance. A window-to-wall ratio of 16%, a visible light transmittance of 0.62, and a glare of 0.52 can meet the daylighting requirements and standards. A design change in the window position helps to obtain annual sunlight exposure within 10% while maintaining high daylighting performance. When installed in the upper position of the wall with a higher sill and lintel height, glazing with a window-to-wall ratio of 16% and a visible light transmittance of 0.62 functions well without creating glare. The significant findings benefit all stakeholders in improving daylighting strategies in tropical climates and satisfying building standards

Effects of dietary supplementation of fish and vegetable oils on the growth performance and muscle compositions of the freshwater prawn Macrobrachium rosenbergii

The present investigation was conducted to assess the suitability of three vegetable oils (sunflower oil, coconut oil and castor oil) as an alternative dietary lipid source for cod liver oil to culture Macrobrachium rosenbergii post larvae (PLs). The experimental feeds contained 40% protein with separately incorporated three vegetable oils and cod liver oil. The feeding trial was conducted on M. rosenbergii PL for 60 days. In the final day of the experimental period, the survival rate, weight gain, length gain, specific growth rate and protein efficiency ratio of prawns showed no significance (P > 0.05) between sunflower oil and cod liver oil incorporated feed fed groups. The coconut oil and castor oil showed lower performance when compared with cod liver oil. The present result showed biochemical accumulation of total protein, amino acids, carbohydrate and lipid in experimental groups. Also there is no significant difference in ash and mineral (Na+ and K+) contents. Among the tested diets, the recorded growth rate and biochemical constituents of sunflower oil and cod liver oil incorporated feed fed groups were similar. The present results revealed that the sunflower oil was on par with cod liver oil. Hence, the sunflower oil can be incorporated in feed formulation for M. rosenbergii PL culture. It can be concluded that the coconut oil and castor oil are not ideal vegetable lipid source with these concentrations which produced lower performance in survival, growth and biochemical compositions of M. rosenbergii PL

Unusual presentation of a vascularized iris lesion in an infant

We report an unusual presentation of a 10-month-old girl with left eye (LE) redness and watering. Evaluation showed an iris vascular lesion and lens opacity in her LE. Child underwent USG B-scan and ultrasound biomicroscopy, by which an extensive mass lesion arising from iris and ciliary body with absent calcification was revealed. Following extensive evaluation, child underwent cataract extraction and trans-scleral total excision of the mass lesion. Histopathology proved it as juvenile xanthogranuloma (JXG) with vascular proliferation. JXG is a rare benign self-limiting dermatologic disorder affecting mainly infants and small children. Ocular lesions are the most common extracutaneous manifestation. Cataract in JXG is less frequently reported. This case is reported due to its rarity and as it presented solely as an intraocular lesion with combined diffuse infiltration into ciliary body and cataract which is unusual. Early recognition and systematic approach helped in sight saving and organ salvaging

A report on a series of nanophthalmos with histopathology and immunohistochemistry analyses using light microscopy

We aimed to study the histopathological and immunohistochemistry features in clinically diagnosed cases of nanophthalmos using light microscopy. This was an observational comparative study. We enrolled four eyes of four consecutive patients with nanophthalmos and visually significant cataract, who underwent cataract surgery with prophylactic posterior sclerostomy. Histological analysis of the excised scleral tissue was done and compared with age-matched cadaver controls between January 2021 and October 2021. Hematoxylin and Eosin (H&E) stains were used for histological analysis, and was further supplemented with immunohistochemistry (IHC) and immunofluorescence (IF) analyses using a simple light microscope. The immunostained sections were analyzed using confocal microscope for the fibronectin expression level. The main outcome measure was demonstration of histological changes of sclera in nanophthalmic eyes undergoing cataract surgery. Light microscopic features of nanophthalmos revealed thick fibers with fraying and lightly stained cores, irregular serrated edges, and randomly interspersed fibroblasts compared to regular arrangement of collagen fibers seen in cadaver controls. Immunohistochemistry analysis with anti-fibronectin antibody showed strong positivity in clustered fibers in nanophthalmos, and less intense diffuse staining in cadaver tissue. Histoclinical correlation was observed in one nanophthalmic scleral tissue with axial length less than 17 mm showing severe disorganization with diffuse collagenization, loss of fibrillary architecture compared to another specimen with axial length more than 17 mm. Simple, cost-effective light microscopy using basic stains was effective in identifying the characteristic histopathological features in nanophthalmic eyes, and this was further highlighted by immunohistochemistry and immunofluorescence analyses

SDG 15 life on land: a review of sustainable fashion design processes: upcycling waste organic yarns

The fashion industry has had a significant impact on the environment and overall global sustainability. Evidence shows it is the most polluting industry and the largest consumer of water, accounting for 20% of global water wastage detrimentally affecting both life on land and underwater. As such a few key stakeholders in the fashion industry have begun undertaking key preventative measures. These include but are not limited to the use of organic cotton crops, reduction of water use throughout the production chain, the implementation of a zero-waste patternmaking technique, second-hand shops, recycling of production materials, recycling discarded fishing nets into nylon fibre and increasing the use of biodegradable fibres, crop’s waste fibres, bio-based fibres and bio-textile processes and renewable sources like bamboo and hemp. The review presented in this chapter examines the fashion production cycle, the use of alternative organic materials and recycling processes for the sustainable production of yarns whilst exploring the connections between the Sustainable Development Goals (SDGs) 15 Life on Land and 14 Life below Water