A real time application on Neutrosophic Nano Soft Topology

In this paper, we introduce Neutrosophic Nano Topological Space inducedby soft set. The “Neutrosophic Nano Soft Topological Space”(NNSTS) is generated by soft lower approximation, soft upper approximation and soft boundary region. The approximations are derived by the soft relation. Also a real life problem is converted to Neutrosophic Nano Soft Topology and solved by calculating score value.Publisher's Versio

Effects of twin pregnancy chorionic properties on fetal outcomes: a comparative study

Background: Twins carry significant risks to both mothers and babies. The purpose of this study was to evaluate chorionicity and its impact on perinatal outcomes in twins.Methods: This prospective observational study was conducted in the department of obstetrics and gynecology, Government T. D. Medical College, Alappuzha, Kerala. A total of 106 cases of twin pregnancies were included in the prospective descriptive study. Based on the ultrasound results and methods of the postpartum pathologic examination of the placental membranes, the cases were divided into the twin group with monochorionic diamniotic (MCDA) and twin group with dichorionic diamniotic (DCDA group). The relationships of different chorionic properties and fetal outcomes were determined by comparing various fetal outcomes.Results: Among 106 twin pregnancies, 61.3% were DCDA twins, 38.7% were MCDA. Average maternal age of monochorionic twin was 25 and that of dichorionic twin was 27. Perinatal mortality of monochorionic twin was 14.7% when compared to 8.6% for dichorionic twin. The mean gestational age for monochorionic twin pregnancy was 34.78 weeks whereas it was 35.91 weeks for dichorionic pregnancy. Elective and emergency LSCS was done more for dichorionic twin pregnancies compared to monochorionic twin pregnancies. Low Apgar scores were seen in monochorionic twins compared to dichorionic twins.Conclusions: The incidence of fetal outcomes in the monochorionic group was inferior to those in the dichorionic group. The fetal outcomes may be improved by determining the chorionic properties in early pregnancy by using ultrasound and consequently planning for pregnancy monitoring and intervention

A cross sectional study on immunization status of anganwadi children in a rural area of north Kerala, India

Background: The current scenario depicts that immunization coverage has been steadily increasing but the average level remains far less than the desired. Though there is increased accessibility of health care services in rural areas, its utilization is low. Hence the present study is undertaken in an attempt to assess immunization status of children between 2 to 5 years of age enrolled in anganwadi centers in a field practice area of Pariyaram Medical College. The aim of the study was to assess the immunization status of anganwadi children in a rural area of north Kerala, India.Methodology: A cross Sectional Study was done among anganwadi Children between ages 2 to 5 years from January 2013 to March 2013 at Cheruthazham. Cluster sampling method was used. Each Anganwadi centre was considered as a single cluster and all children from the selected anganwadi centers were included in the study. Data was analyzed by SPSS Version 17, Microsoft excel 2007. Results: 94% of children were fully immunized with BCG, DPT, OPV and measles. Coverage was highest for BCG, DPT-1 and OPV-1 (100%) and least for measles, 94%. The major cause of incomplete immunization was postponement of immunization due to inter current illness of the child. There is only marginal difference in immunization coverage according to gender, religion or education of parents. Conclusion: Regular health education sessions, and regular reminders and removal of misconceptions prevailing among people will solve the problems of non-immunization.

A study on nutritional status of Anganwadi children in a rural area of North Kerala

Background: Malnutrition being the biggest contributor to child mortality and morbidity is highly prevalent among preschool children in India. The state of Kerala which tops the list in most of the health indicators in India is no exception to wide prevalence of malnutrition in children. Objective: To assess the nutritional status of Anganwadi children aged 2-5 years in a rural area of North Kerala. Materials and Methods: A cross-sectional study was done among Anganwadi children between 2 and 5 years of age from January 2013 to March 2013 at Cheruthazham, Kannur district of Kerala. Cluster sampling method was used for the study. Height and weight of the children were measured using the standard anthropometric equipment, and body mass index was calculated. Data were analyzed by SPSS version 17, Microsoft Excel 2007. Results: In accordance with the WHO criteria, 14.6% of children were underweight; 10.6% stunted and 16.6% were wasted. Underweight, stunting, and wasting were most prevalent in 2-3-year-old children and minimum among 3-4-year-old children. Underweight and wasting were more prevalent among female children than their male counterparts. Stunting was more in male children. Conclusion: Results of the present study showed that the nutritional status of the children in studied population was good comparing with other studies. Nutrition, health education and good access, and utilization of healthcare can be very effective interventions which could result in substantial reduction in undernutrition in children

Anonymity handling and sensor object modeling for pervasive environments using VISA processing

Pervasive computing devices are configured for anywhere at any time services to adapt the changes in the dynamic environment with respect to the user mobility.The paper proposes a salient model for a log based anonymity handling in pervasive networks.The model defines a resource registry and sensor object modeling.Associability between the nodes are configured with an allied user interface in the environment.Resource registry refers to a record of information about the sensor nodes.A log book is maintained to keep track of the service discovery issues.New device enquiry, registration and adaption are major issues in such pervasive devices.These issues lead to unacknowledged communication that causes anonymity.This paper defines and discusses the presence of anonymity in pervasive environments due to aforementioned issues

Correlation of acute suppurative otitis media with infant feeding position

Background: Acute otitis media (AOM) is the most common childhood illness necessitating medical therapy for children younger than 5 years. Long-term and exclusive breastfeeding is associated with protection against AOM. However, faulty feeding position and habits can lead to the occurrence of AOM in infants. Objectives: The aim of this study is to assess the risk of occurrence of AOM with faulty feeding positions during the 1st year of life. Materials and Methods: All breastfed infants <1 year with a provisional diagnosis of AOM, during August 2015 - January 2016 (6 months), were included in the study. Syndromic children, children with craniofacial anomalies, bottle-fed infants, and those not willing to participate in the study were excluded from the study. Demographic details and detailed history, especially, the feeding position were collected from the parents. Diagnosis of AOM was confirmed by a senior ENT surgeon after otoscopic examination. Results: 118 children with AOM were statistically analyzed. They aged between 1 month and 12 months with a mean of 6.8 and standard deviation of 4.1 months. There were 68 (57.62%) males and 50 (42.37%) females. No statistical significance was observed for sex or laterality with AOM. A statistically significant correlation was observed between AOM and age groups, AOM and position of the baby. Conclusion: In this study, we have observed that feeding the infant in supine position significantly increases the risk of AOM in infants

Role of Relative Humidity in Processing and Storage of Seeds and Assessment of Variability in Storage Behaviour in Brassica

The role of relative humidity (RH) while processing and storing seeds of Brassica spp. and Eruca sativa was investigated by creating different levels of relative humidity, namely, 75%, 50%, 32%, and 11% using different saturated salt solutions and 1% RH using concentrated sulphuric acid. The variability in seed storage behaviour of different species of Brassica was also evaluated. The samples were stored at 40±2°C in sealed containers and various physiological parameters were assessed at different intervals up to three months. The seed viability and seedling vigour parameters were considerably reduced in all accessions at high relative humidity irrespective of the species. Storage at intermediate relative humidities caused minimal decline in viability. All the accessions performed better at relative humidity level of 32% maintaining seed moisture content of 3%. On analyzing the variability in storage behaviour, B. rapa and B. juncea were better performers than B. napus and Eruca sativa

Ethnomedical survey of plants used by the Orang Asli in Kampung Bawong, Perak, West Malaysia

<p>Abstract</p> <p>Background</p> <p>A qualitative ethnomedical survey was carried out among a local Orang Asli tribe to gather information on the use of medicinal plants in the region of Kampung Bawong, Perak of West Malaysia in order to evaluate the potential medicinal uses of local plants used in curing different diseases and illnesses.</p> <p>Methods</p> <p>Sixteen informants ranging in age from 35 to 65 years were interviewed. A total of 62 species of plants used by Orang Asli are described in this study based on field surveys and direct face to face communication. These plants belonged to 36 families and are used to treat a wide range of discomforts and diseases.</p> <p>Results</p> <p>The results of this study showed that majority of the Orang Asli, of Kampung Bawong are still dependent on local plants as their primary source of medication. As the first ethnomedical study in this area, publishing this work is expected to open up more studies to identify and assess the pharmacological and toxicological action of the plants from this region.</p> <p>Conclusions</p> <p>Preservation and recording of ethnobotanical and ethnomedical uses of traditional medicinal plants is an indispensable obligation for sustaining the medicinal and cultural resource of mankind. Extensive research on such traditional plants is of prime importance to scientifically validate their ethnomedical claims.</p

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

<p>Abstract</p> <p>Background</p> <p>Increasing evidence indicates that the interaction between the CXC chemokine receptor-4 (CXCR4) and its ligand CXCL12 is critical in the process of metastasis that accounts for more than 90% of cancer-related deaths. Thus, novel agents that can downregulate the CXCR4/CXCL12 axis have therapeutic potential in inhibiting cancer metastasis.</p> <p>Methods</p> <p>In this report, we investigated the potential of an agent, plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone), for its ability to modulate CXCR4 expression and function in various tumor cells using Western blot analysis, DNA binding assay, transient transfection, real time PCR analysis, chromatin immunoprecipitation, and cellular migration and invasion assays.</p> <p>Results</p> <p>We found that plumbagin downregulated the expression of CXCR4 in breast cancer cells irrespective of their HER2 status. The decrease in CXCR4 expression induced by plumbagin was not cell type-specific as the inhibition also occurred in gastric, lung, renal, oral, and hepatocellular tumor cell lines. Neither proteasome inhibition nor lysosomal stabilization had any effect on plumbagin-induced decrease in CXCR4 expression. Detailed study of the underlying molecular mechanism(s) revealed that the regulation of the downregulation of CXCR4 was at the transcriptional level, as indicated by downregulation of mRNA expression, inhibition of NF-κB activation, and suppression of chromatin immunoprecipitation activity. In addition, using a virtual, predictive, functional proteomics-based tumor pathway platform, we tested the hypothesis that NF-κB inhibition by plumbagin causes the decrease in CXCR4 and other metastatic genes. Suppression of CXCR4 expression by plumbagin was found to correlate with the inhibition of CXCL12-induced migration and invasion of both breast and gastric cancer cells.</p> <p>Conclusions</p> <p>Overall, our results indicate, for the first time, that plumbagin is a novel blocker of CXCR4 expression and thus has the potential to suppress metastasis of cancer.</p