3,115 research outputs found
Parent-child interaction in Nigerian families: conversation analysis, context and culture
This paper uses a conversation analysis (CA) approach to explore parent child interaction (PCI) within Nigerian families. We illustrate how speech and language therapists (SLTs), by using CA, can tailor recommendations according to the interactional style of each individual family that are consonant with the family’s cultural beliefs. Three parent-child dyads were videoed playing and talking together in their home environments. The analysis uncovered a preference for instructional talk similar to that used in the classroom. Closer examination revealed that this was not inappropriate when considering the context of the activities and their perceived discourse role. Furthermore, this was not necessarily at the expense of responsivity or semantic contingency. The preference for instructional talk appeared to reflect deeply held cultural beliefs about the role of adults and children within the family and it is argued that the cultural paradigm is vitally important to consider when evaluating PCI. Given a potential risk that such young children may be vulnerable in terms of language difficulties, we offer an example of how PCI can be enhanced to encourage language development without disrupting the naturally occurring talk or the underlying purpose of the interaction
Radon exposure and cancers other than lung cancer in Swedish iron miners.
Data are presented on the risks of cancers other than lung cancer in a cohort of iron miners from northern Sweden occupationally exposed to elevated levels of the radioactive gas radon. Compared with rates for the four northernmost counties of Sweden, mortality was increased for all cancers other than lung cancer (ratio of observed to expected deaths 1.21, 95% confidence interval 1.03-1.41), stomach cancer (ratio of observed to expected deaths 1.45, 95% confidence interval 1.04-1.98), and rectal cancer (ratio of observed to expected deaths 1.94, 95% confidence interval 1.03-3.31). Despite these overall increases, mortality was not significantly associated with cumulative exposure to radon, either for all cancers other than lung cancer or for any site of cancer other than lung cancer individually. However, the data from this cohort on its own have limited power; and for several sites of cancer the data in this study would be consistent with a radon-related increase. Further study of cancers other than lung cancer in populations exposed to radon is required
Unfolding dynamics of proteins under applied force
Understanding the mechanisms of protein folding is a major challenge that is being addressed effectively by collaboration between researchers in the physical and life sciences. Recently, it has become possible to mechanically unfold proteins by pulling on their two termini using local force probes such as the atomic force microscope. Here, we present data from experiments in which synthetic protein polymers designed to mimic naturally occurring polyproteins have been mechanically unfolded. For many years protein folding dynamics have been studied using chemical denaturation, and we therefore firstly discuss our mechanical unfolding data in the context of such experiments and show that the two unfolding mechanisms are not the same, at least for the proteins studied here. We also report unexpected observations that indicate a history effect in the observed unfolding forces of polymeric proteins and explain this in terms of the changing number of domains remaining to unfold and the increasing compliance of the lengthening unstructured polypeptide chain produced each time a domain unfolds
Algebraic inversion of the Dirac equation for the vector potential in the non-abelian case
We study the Dirac equation for spinor wavefunctions minimally coupled to an
external field, from the perspective of an algebraic system of linear equations
for the vector potential. By analogy with the method in electromagnetism, which
has been well-studied, and leads to classical solutions of the Maxwell-Dirac
equations, we set up the formalism for non-abelian gauge symmetry, with the
SU(2) group and the case of four-spinor doublets. An extended isospin-charge
conjugation operator is defined, enabling the hermiticity constraint on the
gauge potential to be imposed in a covariant fashion, and rendering the
algebraic system tractable. The outcome is an invertible linear equation for
the non-abelian vector potential in terms of bispinor current densities. We
show that, via application of suitable extended Fierz identities, the solution
of this system for the non-abelian vector potential is a rational expression
involving only Pauli scalar and Pauli triplet, Lorentz scalar, vector and axial
vector current densities, albeit in the non-closed form of a Neumann series.Comment: 21pp, uses iopar
Library technician course recognition: meeting the challenge of a distributed national education program
This paper looks at the challenges presented for the Australian Library and Information Association by its role as the professional association responsible for ensuring the quality of Australian library technician graduates. There is a particular focus on the issue of course recognition, where the Association?s role is complicated by the need to work alongside the national quality assurance processes that have been established by the relevant technical education authorities. The paper describes the history of course recognition in Australia; examines the relationship between course recognition and other quality measures; and describes the process the Association has undertaken recently to ensure appropriate professional scrutiny in a changing environment of accountability
Exploring how gifts are discovered and why talents develop in sport
This thesis has attempted to advance knowledge and understanding of giftedness and talent in sport. Difficulties concerning conceptual clarity and issues concerning the origin of talent have slowed the advancement of this field of inquiry. By recognising the divisions that have occurred within the literature due to approach and presupposition, Gagne's (2000) Differentiated Model Of Giftedness and Talent was applied to reorganise the literature and establish a more sturdy conceptual base from which to launch new research. From this view, it became more appropriate to divide and describe talent as the discovery of giftedness and the development of talent. By reorganising previous research with this distinction, previous questions became inappropriate and new avenues of approach were revealed. In the past, research had questioned how talents develop and how gifts could be used to predict talent. However, it now became appropriate to consider how gifts are discovered and why talent develops. To this end, phenomenological interviews were conducted with expert coaches, gifted individuals and their families in an effort to explore how gifts were discovered and why individuals committed themselves to developing talent. This approach facilitated the reconstruction of subjective experience which was necessary to explore the multidimensional and interdependent nature of talent. The results gave a deep insight into the views and experiences of people who were, or who understood giftedness and talent. To express these findings, a new empirically based model has been proposed to explain how gifts are discovered and why talents develop.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
A map of OMC-1 in CO 9-8
The distribution of 12C16O J=9-8 (1.037 THz) emission has been mapped in
OMC-1 at 35 points with 84" resolution. This is the first map of this source in
this transition and only the second velocity-resolved ground-based observation
of a line in the terahertz frequency band. There is emission present at all
points in the map, a region roughly 4' by 6' in size, with peak antenna
temperature dropping only near the edges. Away from the Orion KL outflow, the
velocity structure suggests that most of the emission comes from the OMC-1
photon-dominated region, with a typical linewidthof 3-6 km/s. Large velocity
gradient modeling of the emission in J=9-8 and six lower transitions suggests
that the lines originate in regions with temperatures around 120 K and
densities of at least 10^(3.5) cm^(-3) near theta^(1) C Ori and at the Orion
Bar, and from 70 K gas at around 10^(4) cm^(-3) southeast and west of the bar.
These observations are among the first made with the 0.8 m Smithsonian
Astrophysical Observatory Receiver Lab Telescope, a new instrument designed to
observe at frequencies above 1 THz from an extremely high and dry site in
northern Chile.Comment: Minor changes to references, text to match ApJ versio
Prognostic factors for disease progression in advanced Hodgkin's disease: an analysis of patients aged under 60 years showing no progression in the first 6 months after starting primary chemotherapy.
The aim of this study was to determine whether a very high-risk group based on presenting characteristics could be identified in patients with advanced Hodgkin's disease who may benefit from high-dose chemotherapy (HDCT). Between 1975 and 1992, 453 previously untreated patients aged under 60 years who did not progress in the first 6 months after the start of standard chemotherapy had their hospital notes reviewed. The outcomes analysed were early disease progression (in the 6- to 18-month window following the start of chemotherapy) and disease progression in the whole of the follow-up period. A Cox regression analysis was used to investigate the combined effects of a number of presenting characteristics on these outcomes. Despite the presence of factors with significant effects on the relative rate of progression, the absolute effects in a group identified as having the poorest prognosis were not especially poor. No group could be defined with a freedom from progression rate of less than 70% over 6-18 months, and the worst prognostic group, which included only 53 patients, had an overall freedom from progression rate of 57% at 5 years. Four other reported prognostic indices were evaluated using our data set, but none of the indices was more successful in identifying a very high-risk group. It has not been possible to define a sufficiently high-risk group of patients with Hodgkin's disease based on presenting characteristics for whom HDCT could be advised as part of primary treatment. The search for more discriminating prognostic factors identifying vulnerable patients with a high risk of relapse must continue before a role can be found for HDCT following conventional chemotherapy in patients without disease progression
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