Offenders’ perceptions of the UK prison smoking ban

Purpose Despite overall reductions in levels of smoking in the UK, rates of offender smoking remain high. In 2016, it was announced that prisons in England and Wales would gradually introduce a smoking ban. The purpose of this paper is to explore offenders’ perceptions around the upcoming smoking ban. Design/methodology/approach A total of eight focus groups were conducted in four prisons across the North of England. Both smoking and non-smoking offenders participated in the focus groups, and thematic analysis was used to explore the findings. Findings Themes generated from the data were “freedom and rights”, “the prison environment” and “guiding support”. Participants discussed how the smoking ban was viewed as a punishment and restricted their freedom, with perceptions as to why the ban was being implemented centring around others trying to control them. Participants expressed concerns around the financial implications of the smoking ban on already stretched prison resources. Participants also recommended improving the nicotine replacement therapy on offer, and increasing the range of leisure activities within the prison to prepare for the smoking ban. Originality/value Overall, it was apparent that participants’ awareness of the smoking ban was generally poor. It is recommended that offenders need to be made more aware of the smoking cessation support they will receive and given the opportunity to ask questions about the smoking ban. Increasing offenders’ awareness of the ban may reduce stress associated with a perceived lack of choice around their smoking behaviours

The Mediation Effects of Adaptive Blindness Strategies on the Relation Between Institutional Betrayal From Military Sexual Assault and Mental Health Symptoms

Military sexual assault is a serious and prevalent issue. The frequency with which military sexual assault occurs and the nature of the response to these events within the military system may contribute to institutional betrayal. Institutional betrayal is the failure of an institution, such as the military, to prevent sexual assault from occurring and/or the failure to support a survivor after sexual assault. Adaptive blindness strategies are forms of coping strategies that help individuals navigate a relationship they depend on when there is a betrayal. Two adaptive blindness strategies are self-blame and minimization. Although the adaptive blindness strategies may allow sexual assault survivors to navigate their experiences with sexual assault and institutional betrayal, it was predicted that both self-blame and minimization would be associated with more depressive symptoms and posttraumatic stress disorder (PTSD) symptoms. Data were collected using an online survey of 153 female service members who endorsed military sexual assault. Self-blame had significant mediation effects on the relation between institutional betrayal for both depressive symptoms and PTSD symptoms suggesting it may act as an adaptive blindness strategy. In contrast, minimization did not mediate the association between institutional betrayal and mental health outcomes. In addition, variables that may possibly impact the utilization of adaptive blindness strategies, specifically, years served and unit support, were analyzed via moderation models. Years served in the military did not have significant moderation effects on the relation between institutional betrayal and the adaptive blindness strategies. Unit support did significantly moderate the association between institutional betrayal and minimization, specifically, more unit support was associated with increased minimization in response to institutional betrayal. Therefore, minimization may act as an adaptive blindness strategy under conditions of high unit support. These findings should be incorporated into our understanding of how women service members may respond to institutional betrayal regarding sexual assault thus informing Department of Defense’s policies and therapists’ conceptualization of women service members to provide culturally competent care. The findings also add support for the use of the betrayal trauma theory (Freyd, 1994) with the population of women service members

The Effects of Military Sexual Trauma and Depressive Symptoms on Reintegration

Reintegration is a challenge for many veterans returning to civilian roles after military service. Difficulties range from an assortment of issues such as self-care to community participation. Military sexual trauma may be an experience that alters or changes veterans and result in difficulty in reintegration. Specifically, it was predicted that military sexual trauma would indirectly affect reintegration, via depressive symptoms. In addition, locus of control was predicted to play a role in how military sexual trauma impacts reintegration with external locus of control acting as a buffer. Participants were a cross-sectional community sample of both female veterans who reported having experienced and not experienced. They completed an online survey. Both endorsing military sexual harassment and military sexual assault predicted reintegration difficulties; however, depressive symptoms fully mediated associations between both forms of military sexual trauma (i.e., sexual harassment and sexual assault) and reintegration difficulties. Locus of control did not significantly moderate the pathway between military sexual trauma and reintegration nor the pathway between military sexual trauma and depressive symptoms. In fact, the significant direct associations of locus of control on depressive symptoms and reintegration were in the opposite direction of what was predicted in that external locus of control was associated with more reintegration difficulties and depressive symptoms. The results suggest the importance of reducing military sexual trauma and reintegration assistance programs

Structure-Activity Relationship Studies of Synthetic Cathinones and Related Agents

Synthetic cathinones and related agents represent an international drug abuse problem, and at the same time an important class of clinically useful compounds. Structure-activity relationship studies are needed to elucidate molecular features underlying the pharmacology of these agents. Illicit methcathinone (i.e., MCAT), the prototype of the synthetic cathinone class, exists as a racemic mixture. Though the differences in potency and target selectivity between the positional and optical isomers of synthetic cathinones and related agents have been demonstrated to have important implications for abuse and therapeutic potential, the two MCAT isomers have never been directly compared at their molecular targets: the monoamine transporters (MATs). Additionally, previous studies have found that the carbonyl oxygen atom can be replaced with a methoxy group, but this results in two chiral centers (i.e., four possible optical isomers for synthesis and evaluation). Here, the individual isomers of MCAT, their racemate, and achiral MCAT analogs were prepared where necessary, and examined in vitro and in silico at the MATs. All agents were active as substrates, with a rank order of potency suggesting that α-position chirality, in either configuration, is favored but not required, with the S(-) configuration slightly preferred. Either chiral center removal approach resulted in a reduction in potency, suggesting both favorable interactions with the α-methyl, and limited bulk tolerance. To further investigate this possibility, docking studies were conducted using homology models of the MATs. Common binding modes were identified that were similar to the binding mode of S(+)amphetamine co-crystallized at drosophila DAT. Taken together, these studies supported our conclusions, as steric hindrance was observed in the α-methyl region of the proposed binding site for the R(+)MCAT isomer. Inclusion of the original synthetic cathinones among Schedule I controlled substances has driven the clandestine development of a second generation of agents, resulting in an array of new synthetic cathinones diverse in structure and effect.Pyrrolidinophenones are a major constituent of second-generation bath salts. Little is known about their structure-activity relationships. Here, we have synthesized and examined a series of aryl-substituted pyrrolidinophenone analogs, as well as an achiral pyrrolidinophenone analog, utilizing novel synthetic chemistry and an innovative cell-based epifluorescence Ca2+ imaging technique. Herein, we evaluated the neurochemical properties of these novel compounds at the dopamine transporter (DAT), considered to exert a major role in actions of drugs of abuse. For future structure-activity relationship studies, additional analogs of synthetic cathinone-related agents were produced using novel synthetic approaches, including analogs and isomers of known amphetamine drugs of abuse. Finally, though much has been learned about the role of the dopamine and serotonin transporters in the mechanisms of action of synthetic cathinones, the role of the norepinephrine transporter is poorly understood. Homology models of the human norephinephrine transporter were built and docking studies conducted to inform the study of MAT ligand selectivity, activity, and binding. In conclusion, these studies represent progress towards the establishment of comprehensive structure-activity relationships for synthetic cathinones and related agents. Particular emphasis was placed on the SAR of the phenylalkylamine α-carbon in the synthetic cathinone context, and the role of the norepinephrine transporter in their activity

Pion electromagnetic form factor from full lattice QCD

We present preliminary results from the first calculation of the pion electromagnetic form factor at physical light quark masses. This form factor parameterises the deviations from the behaviour of a point-like particle when a photon hits the pion. These deviations result from the internal structure of the pion and can thus be calculated in QCD. We use three sets (different lattice spacings) of n_f=2+1+1 lattice configurations generated by the MILC collaboration. The Highly Improved Staggered Quark formalism (HISQ) is used for all of the sea and valence quarks. Using lattice configurations with u/d quark masses very close to the physical value is an advantage, as we avoid the chiral extrapolation. We study the shape of the vector (f_+) form factor in the q^2 range from 0 to -0.12 GeV^2 and extract the mean square radius, <r^2_v>. The shape of the vector form factor and the resulting radius is compared with experiment

Nonperturbative tests of the renormalization of mixed clover-staggered currents in lattice QCD

The Fermilab Lattice and MILC collaborations have shown in one-loop lattice QCD perturbation theory that the renormalization constants of vector and axial-vector mixed clover-asqtad currents are closely related to the product of those for clover-clover and asqtad-asqtad (local) vector currents. To be useful for future higher precision calculations this relationship must be valid beyond one-loop and very general. We test its validity nonperturbatively using clover and Highly Improved Staggered (HISQ) strange quarks, utilising the absolute normalization of the HISQ temporal axial current. We find that the renormalization of the mixed current differs from the square root of the product of the pure HISQ and pure clover currents by 2−3%. We also compare discretization errors between the clover and HISQ formalisms

Exploring the application of the Prototype Willingness Model to weight loss dieting behaviour among UK adults

Frequent weight loss dieting leads to increased BMI and is associated with eating pathologies. Theoretical models can aid the development of interventions to reduce risk behaviours such as frequent dieting if they are able to adequately account for the target behaviour. The Prototype Willingness Model (PWM) may be able to account for weight loss dieting as this behaviour is often associated with social images. This study explored whether the PWM could predict weight loss dieting status over and above the Theory of Planned Behaviour (TPB). One hundred and ninety two participants (69% female; mode age 35-44) completed PWM and TPB measures and recorded their height and weight. Males were more likely to be non-dieters than females. Frequent dieters had a higher BMI than non-dieters and rated themselves as more similar to the overweight prototype. Prototype perceptions predicted willingness to eat unhealthy foods alone. Similarity to the overweight prototype predicted weight loss dieting status over and above TPB measures and sex. Further research should explore prototype perceptions in an obese/overweight frequent dieting population as this may be a fruitful direction for developing interventions to reduce weight loss dieting

Alfvén-fast wave coupling in a 2D non-uniform medium

Funding: The authors acknowledge financial support by the UK’s Science and Technology Facilities Council (STFC). R.D. was supported by STFC Doctoral Training Partnership Grant ST/T506436/1. A.N.W. was partially supported by STFC Grant ST/W001195/1.A 2D Cartesian simulation is presented and used to solve the ideal, low-beta, linear magnetohydrodynamics equations. A simulation is used to investigate the propagation of Alfvén waves through inhomogeneities in Alfvén speed and density. In particular, the loss of Alfvén wave energy through coupling to the fast wave, and also the form of the Alfvén wave as it emerges from the inhomogeneous region is studied. Potential applications of this include the magnetospheres of both Jupiter and the Earth. The results show that Alfvén waves can be significantly distorted by a nonuniformity and still propagate through the region efficiently, with relatively small amounts of Alfvén wave energy lost through mode conversion and reflection.Publisher PDFPeer reviewe

A-Site and B-Site Order in (Na\u3csub\u3e1/2\u3c/sub\u3eLa\u3csub\u3e1/2\u3c/sub\u3e)(Mg\u3csub\u3e1/3\u3c/sub\u3eNb\u3csub\u3e2/3\u3c/sub\u3e)O\u3csub\u3e3\u3c/sub\u3e Perovskite

(Na1/2La1/2)(Mg1/3Nb2/3)O3 undergoes a series of phase transitions that involve cation order on the A- and B-sites of the parent perovskite structure. At high temperatures both sites contain a random distribution of cations; below 1275°C a 〈111〉 layering of Mg and Nb leads to the formation of a 1:2 ordered structure with a monoclinic supercell. A second transition was observed at 925°C, where the Na and La cations order onto alternate A-site positions along the 〈001〉 direction of the parent subcell. By quenching samples from above 1275°C to preserve the disorder on the B-site, a fourth variant of this compound was obtained by inducing A-site order through a subsequent anneal at 900°C. Although the changes in structure do not produce significant alterations in the relative permittivity (εr ~ 35), they do have a significant effect on the value of the temperature coefficient of the capacitance