1,355 research outputs found

    The Odd One Out: Felony Murder, The Law of Parties, and the Execution of Non Killers

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    The focus of this research is in the area of the United States death penalty. More specifically, it examines the use of the felony murder rule and the law of parties at both federal and state level. These areas are considered in light of the 8th Amendment as according to the interpretations of the United States Supreme Court. The approach taken in this article is two dimensional: firstly it considers the theoretical approach to the felony murder rule and the law of parties by way of assessing the legislation and precedents at federal level, secondly it examines the law in practice at state level and compares and contrasts them. This article seeks to establish that the law of parties imposing the death penalty on non-triggerman accomplices is arbitrary, inadequate, unjustified and unconstitutional through its violation of the 8th Amendment

    Testing the Limits of Deliberative Constitutionalism

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    Ecological and economic benefits of integrating sheep into viticulture production

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    The integration of crop and livestock systems has been recognized for its potential to reduce the environmental impacts associated with agriculture and improve farmer livelihoods. However, to date, most research has focused on the integration of cattle into crop and pasture systems. Here we examine the integration of sheep into vineyards and assess farmers’ perceived benefits and costs of the practice. Viticulture expansion has led to significant land use change in recent years and new environmental challenges, particularly with respect to herbicide use. Sheep integration into vineyards offers the potential to utilize the synergies of both systems to reduce external inputs, promote soil health, and increase farmer profit. Our study focuses in New Zealand, the world’s 15th largest wine producer, particularly in Marlborough, which produces 75% of the country’s wine. As a result, the case study is an excellent representation of New Zealand viticulture, while also providing unique insights into a novel practice. Using a semi-structured interview and survey, we interviewed fifteen farmers representing five percent of total New Zealand wine production to examine ecological and economic benefits of sheep integration in viticulture systems. We find that seasonal integration of sheep during vine dormancy is common, while integration during the growing season is rare. Overall, farmers perceive significantly more benefits than challenges with the integration of sheep into vineyards, particularly reduced mowing (100% of farmers) and herbicide use (66% of farmers). On average, farmers reported 1.3 fewer herbicide applications annually, saving US 56 per hectare. As well, farmers indicated they were doing 2.2 fewer mows annually saving US 64 per hectare. These results suggest that wide-scale adoption of seasonal integration of sheep and viticulture can provide large ecological benefits and higher profitability vis-à-vis conventional viticulture practices; however, further integration of the two systems may provide even greater benefits not currently realized

    Genetic and biochemical characterization of an acquired subgroup B3 metallo-β-lactamase gene, blaAIM-1, and its unique genetic context in Pseudomonas aeruginosa from Australia

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    Three clinical Pseudomonas aeruginosa isolates (WCH2677, WCH2813, and WCH2837) isolated from the Women's and Children's Hospital, Adelaide, Australia, produced a metallo-β-lactamase (MBL)-positive Etest result. All isolates were PCR negative for known MBL genes. A gene bank was created, and an MBL gene, designated bla, was cloned and fully characterized. The encoded enzyme, AIM-1, is a group B3 MBL that has the highest level of identity to THIN-B and L1. It is chromosomal and flanked by two copies (one intact and one truncated) of an ISCR element, ISCR15. Southern hybridization studies indicated the movement of both ISCR15 and bla within the three different clinical isolates. AIM-1 hydrolyzes most β-lactams, with the exception of aztreonam and, to a lesser extent, ceftazidime; however, it possesses significantly higher k values for cefepime and carbapenems than most other MBLs. AIM-1 was the first mobile group B3 enzyme detected and signals further problems for already beleaguered antimicrobial regimes to treat serious P. aeruginosa and other Gram-negative infections

    Hospital postdischarge intervention trialled with family caregivers of older people in Western Australia: potential translation into practice

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    There is lack of a suitable assessment tool that can be used routinely and systematically by hospital staff to address family caregivers' (FCs') support needs. This paper describes a novel approach to identifying and addressing FCs' needs following hospital discharge of the older person receiving care. SETTING AND PARTICIPANTS: FC recruitment occurred on the patient's discharge from a tertiary hospital in Western Australia; 64 completed the study; 80% were female; mean age 63.2 years. INTERVENTION: The Further Enabling Care at Home (FECH) programme was delivered over the telephone by a specially trained nurse and included: support to facilitate understanding of the patient's discharge letter; caregiver support needs assessment and prioritisation of urgent needs; and collaborative guidance, from the nurse, regarding accessing supports. RESULTS: Sixty-four FCs completed the FECH programme. The top three support needs identified by the FCs were: knowing what to expect in the future (52%), knowing who to contact if they were concerned (52%) and practical help in the home (36%). The telephone-based outreach service worked well and was convenient for the nurse and the FCs, and saved on transport, time and money. Most of the FCs appreciated the systematic approach to identify and articulate their needs and were satisfied with the support they received, mainly navigation through the systems, problem solving, self-care strategies, explanation of illness, symptoms and medication and access to after-hours services. CONCLUSIONS: In order to guide services which may consider adopting this systematic approach to supporting FCs and integrating it into their routine practice, this evaluation of the FECH programme has described the processes implemented and highlighted the factors that hindered or facilitated these processes to engage caregivers with appropriate services in a timely manner. Positive feedback indicated that the programme was a useful addition to hospital discharge planning. TRIAL REGISTRATION NUMBER: ACTRN12614001174673; Results

    The Use of a Scenario-Based Nominal Group Technique to Assess P/CVE Programs: Development and Pilot Testing of a Toolkit

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    Preventing and countering violent extremism (P/CVE) requires coordination among multiple agencies, stakeholders and systems. The complexity of this task (compounded by the variety of P/CVE programming around the world) creates a  challenge for those hoping to develop these initiatives. The purpose of this project was to develop a replicable process and corresponding toolkit to engage multiple stakeholders in consensus building around the efficacy and improvement of nascent, developing or mature systems-level P/CVE programs. As a method, we adapted the process of nominal group technique (NGT), a structured-brainstorming tool that provides an orderly procedure for obtaining qualitative and ranked information from heterogenous participant pools. The technique we developed is based on a case-study approach (“scenario”) which we then tested in three countries (USA, Sweden, and North Macedonia) with existing P/CVE initiatives at different stages of development. We conducted scenario-based NGT sessions in each location and then systematically analyzed the results using iterative qualitative coding based on a common framework. Results were analyzed to achieve consensus on the most common system-level challenges and system-level functions, necessary to overcome those challenges, in each location. Practitioners in each local jurisdiction were then able to utilize the results derived from the NGT for their own purposes, such as advocacy to policy makers, strategic regional P/CVE planning, and ongoing stakeholder engagement. Acknowledgments: This project was funded by the NATO Science for Peace and Security Programme under the award entitled "Evaluation Support for CVE at the Local Level" SPS.MYPG5556, the Swedish Contingency Agency (MSB), and the U.S. Department of Homeland Security (DHS), Science and Technology Directorate (Cooperative Agreement Number: 2015-ST-108-FRG005). The content of this manuscript as well as the views and discussions expressed are solely those of the authors and do not necessarily represent the official views of any of the above institutions, nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. government

    An Experimental Field Study of Delayed Density Dependence in Natural Populations of Aedes albopictus

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    Aedes albopictus, a species known to transmit dengue and chikungunya viruses, is primarily a container-inhabiting mosquito. The potential for pathogen transmission by Ae. albopictus has increased our need to understand its ecology and population dynamics. Two parameters that we know little about are the impact of direct density-dependence and delayed density-dependence in the larval stage. The present study uses a manipulative experimental design, under field conditions, to understand the impact of delayed density dependence in a natural population of Ae. albopictus in Raleigh, North Carolina. Twenty liter buckets, divided in half prior to experimentation, placed in the field accumulated rainwater and detritus, providing oviposition and larval production sites for natural populations of Ae. albopictus. Two treatments, a larvae present and larvae absent treatment, were produced in each bucket. After five weeks all larvae were removed from both treatments and the buckets were covered with fine mesh cloth. Equal numbers of first instars were added to both treatments in every bucket. Pupae were collected daily and adults were frozen as they emerged. We found a significant impact of delayed density-dependence on larval survival, development time and adult body size in containers with high larval densities. Our results indicate that delayed density-dependence will have negative impacts on the mosquito population when larval densities are high enough to deplete accessible nutrients faster than the rate of natural food accumulation

    The biocide triclosan induces (p)ppGpp dependent antibiotic tolerance and alters SarA dependent biofilm structures in Staphylococcus aureus

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    The biocide triclosan is used extensively in both household and hospital settings. The chronic exposure to the biocide occurring in individuals that use triclosan-containing products results in low levels of triclosan present in the human body that has been linked to induction of antibiotic tolerance and altered biofilm formation. Here we aimed to unravel the molecular mechanisms involved in triclosan induced antibiotic tolerance and biofilm formation in Staphylococcus aureus. Triclosan treatment prior to planktonic exposure to bactericidal antibiotics resulted in 1,000 fold higher viable cell counts compared to non-pretreated cultures. Triclosan pretreatment also protected S. aureus biofilms against otherwise lethal doses of antibiotics as shown by live/dead cell staining and viable cell counting. Triclosan mediated antibiotic tolerance in planktonic and biofilm cultures required an active stringent response because a pppGpp0 strain was not protected from antibiotic killing. Incubation of S. aureus with triclosan also altered biofilm structure due to SarA-mediated overproduction of the polysaccharide intercellular adhesin (PIA) in the biofilm matrix. Thus, physiologically relevant concentrations of triclosan can trigger (p)ppGpp dependent antibiotic tolerance as well as SarA dependent biofilm formation

    Posterior Parietal Cortex Dependent Contextual Renewal of Conditioned Positive and Negative Associations

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    Conor Ollendike ’26, Major: Psychology, neuroscience certificate Ashley Sawtelle ’26, Major: Psychology Yamilet Nieves ’26, Major: Neuroscience, Minor: Women and Gender Studies Rachael Layden ’23, Major: Psychology Christopher Walsh ’23, Majors: Biology and Psychology, neuroscience certificate Jose Pena ’25, Major: Neuroscience, Minor: Physics Shelby Bawden ’23, Majors: Biology and Psychology, neuroscience certificate Faculty Mentor: Dr. Victoria Templer, Psychology Recent work suggests the Posterior Parietal Cortex (PPC) is necessary for the renewal of an extinguished conditioned fear response in a novel (ABA), but not a familiar (ABC) context (in ABA/C, slot 1 refers to acquisition; 2- extinction, 3 –renewal). We investigated whether such context-dependent renewal generalizes to positive conditioned stimuli in sham operated control rats and a small cohort of Designer Receptor Activated Only by Designer Drugs (DREADDs) PPC rats after delivery of CNO to inactivate PPC. Control rats renewed positive (light-food) and negative associations (tone-shock) regardless of the renewal context, replicating context dependent renewal in rodents found in previous literature. The positive condition conferred a significantly higher magnitude of renewal compared to the negative condition. When the PPC was deactivated, rats did not renew in both the positive and negative ABC condition but did in the ABA condition. However, when the PPC was active in both the ABC and ABA conditions all subjects renewed both positive and negative associations, matching the sham operated controls. These results suggest the PPC plays a crucial role in renewal of a context dependent conditioned fear response as well as a context dependent conditioned positive response
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