755 research outputs found
A solution to the mu problem in the presence of a heavy gluino LSP
In this paper we present a solution to the problem in an SO(10)
supersymmetric grand unified model with gauge mediated and D-term supersymmetry
breaking. A Peccei-Quinn symmetry is broken at the messenger scale GeV and enables the generation of the term. The boundary
conditions defined at lead to a phenomenologically acceptable version of
the minimal supersymmetric standard model with novel particle phenomenology.
Either the gluino or the gravitino is the lightest supersymmetric particle
(LSP). If the gravitino is the LSP, then the gluino is the next-to-LSP (NLSP)
with a lifetime on the order of one month or longer. In either case this heavy
gluino, with mass in the range 25 - 35 GeV, can be treated as a stable particle
with respect to experiments at high energy accelerators. Given the extensive
phenomenological constraints we show that the model can only survive in a
narrow region of parameter space resulting in a light neutral Higgs with mass
GeV and . In addition the lightest stop
and neutralino have mass GeV and GeV,
respectively. Thus the model will soon be tested. Finally, the invisible axion
resulting from PQ symmetry breaking is a cold dark matter candidate.Comment: 30 pages, 9 figure
Molecular methodologies for improved polymicrobial sepsis diagnosis
Polymicrobial sepsis is associated with worse patient outcomes than monomicrobial sepsis. Routinely used culture-dependent microbiological diagnostic techniques have low sensitivity, often leading to missed identification of all causative organisms. To overcome these limitations, culture-independent methods incorporating advanced molecular technologies have recently been explored. However, contamination, assay inhibition and interference from host DNA are issues that must be addressed before these methods can be relied on for routine clinical use. While the host component of the complex sepsis host–pathogen interplay is well described, less is known about the pathogen’s role, including pathogen–pathogen interactions in polymicrobial sepsis. This review highlights the clinical significance of polymicrobial sepsis and addresses how promising alternative molecular microbiology methods can be improved to detect polymicrobial infections. It also discusses how the application of shotgun metagenomics can be used to uncover pathogen/pathogen interactions in polymicrobial sepsis cases and their potential role in the clinical course of this condition
Issues of alcohol misuse among older people : attitudes and experiences of social work practitioners
This small-scale qualitative research focused on the experiences of social workers vis--vis older people who misuse alcohol. Based in an Older People's Team in the west of Scotland, the study explored service provision for alcohol misuse and examined whether practitioners felt the existing services provided by the Substance Misuse Team were effective in meeting the needs of older people with an alcohol problem. Using semi-structured interviews, data were collected from 18 participants, the majority (14) of whom were female and whose ages ranged from 31 to 54 years. Several key themes emerged including the extent of alcohol problems among older people and the complex reasons that cause older people to misuse alcohol. These reasons commonly related to the increasing challenges of old age. The data also demonstrated that current services are not meeting the needs of older people. Practitioners identified a need for an 'age-specific' approach to target more effectively the complex needs of older people. Recommendations from practitioners included ways to develop new and more effective services, including a more age-specific service, such as providing longer term support in older people's own homes, using a specialised support worker, and increasing staff training on alcohol use among older people
Enacting Productive Dialogue: Addressing the Challenge that Non-Human Cognition Poses to Collaborations Between Enactivism and Heideggerian Phenomenology
This chapter uses one particular proposal for interdisciplinary collaboration – in this case, between early Heideggerian phenomenology and enactivist cognitive science – as an example of how such partnerships may confront and negotiate tensions between the perspectives they bring together. The discussion begins by summarising some of the intersections that render Heideggerian and enactivist thought promising interlocutors for each other. It then moves on to explore how Heideggerian enactivism could respond to the challenge of reconciling the significant differences in the ways that each discourse seeks to apply the structures it claims to uncover
Modal testing of offshore rock lighthouses around the British Isles
EURODYN 2017, 2017-09-10, 2017-09-13, RomeThis is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Given that 95 per cent of the UK’s international trade is transported by sea, and as a vital complement to fallible virtual navigational aids such as GPS, rock-mounted lighthouses constructed in the 19th century have a crucial role to play in safe navigation. However the longevity of these historical structures is threatened by extreme weather so in the UK, the General Lighthouse Authorities comprising Trinity House, the Northern Lighthouse Board and the Commissioners of Irish Lights are supporting three British universities in a program of linked experimental and analytical investigations of full-scale performance under extreme wave loading. The aim is to use structural models calibrated by modal testing to deduce wave loading from response recorded by long-term monitoring. The paper describes the procedures for modal testing, taking into account the constraints on access, logistics, unfamiliar layout and time. The test program sequentially covered Les Hanois, Wolf Rock, Longships and Bishops Rock lighthouses over summer 2016 followed by Fastnet Rock in December 2016. Some conventional techniques of forced and ambient vibration testing were used along with some unusual excitation methods. Results from the measurements and observations on the particular challenges associated with testing two of these iconic structures are presented.The research was funded by EPSRC grant EP/N022955/
Color Superconductivity from Supersymmetry
A supersymmetric composite model of color superconductivity is proposed.
Quarks and diquarks are dynamically generated as composite fields by a newly
introduced strong gauge dynamics. It is shown that the condensation of the
scalar component of the diquark supermultiplet occurs when the chemical
potential becomes larger than some critical value. We believe that the model
well captures aspects of the diquark condensate behavior and helps our
understanding of the diquark dynamics in real QCD. The results obtained here
might be useful when we consider a theory composed of quarks and diquarks.Comment: 4 pages, 2 figures, An error in Eq.(10) correcte
Observations from the EEFIT-TDMRC mission to Banda Aceh, Indonesia to investigate the recovery from the 2004 Indian Ocean Tsunami
On 26th December 2004 a subduction zone earthquake of magnitude Mw 9.3 struck off the coast of Sumatra in Indonesia. A large area of the Indian Ocean seabed was vertically displaced, and as a result a tsunami wave was generated that went on to affect many countries around the world. One of the worst hit places was the Aceh province of Sumatra where the capital city, Banda Aceh, experienced serious ground shaking and significant sea water inundation. In Indonesia at least 126,732 people were killed, a further 93,652 people were confirmed missing and 533,770 people were displaced. In 2022, nearly 20 years on from the disaster, engineers and scientists from the UK Earthquake Engineering Field Investigation Team (EEFIT) and from the Indonesian Tsunami and Disaster Mitigation Research Centre (TDMRC) conducted a joint longterm recovery mission. This paper reflects on how a society rebuilds after such a devastating loss and what lessons can be learnt as a community for future disaster risk reduction. The scope of the paper includes the rapid assessment of post-disaster housing, community infrastructure and preparedness measures
Heterotic Cosmic Strings
We show that all three conditions for the cosmological relevance of heterotic
cosmic strings, the right tension, stability and a production mechanism at the
end of inflation, can be met in the strongly coupled M-theory regime. Whereas
cosmic strings generated from weakly coupled heterotic strings have the well
known problems posed by Witten in 1985, we show that strings arising from
M5-branes wrapped around 4-cycles (divisors) of a Calabi-Yau in heterotic
M-theory compactifications, solve these problems in an elegant fashion.Comment: 25 pages, v2: section and references adde
Phases of Chiral Gauge Theories
We discuss the behavior of two non-supersymmetric chiral SU(N) gauge
theories, involving fermions in the symmetric and antisymmetric two-index
tensor representations respectively. In addition to global anomaly matching, we
employ a recently proposed inequality constraint on the number of effective low
energy (massless) degrees of freedom of a theory, based on the thermodynamic
free energy. Several possible zero temperature phases are consistent with the
constraints. A simple picture for the phase structure emerges if these theories
choose the phase, consistent with global anomaly matching, that minimizes the
massless degree of freedom count defined through the free energy. This idea
suggests that confinement with the preservation of the global symmetries
through the formation of massless composite fermions is in general not
preferred. While our discussion is restricted mainly to bilinear condensate
formation, higher dimensional condensates are considered for one case. We
conclude by commenting briefly on two related supersymmetric chiral theories.Comment: 23 pages, 2 figures, ReVTeX, improved forma
Increasing secondary resistance to fluoroquinolones amongst Helicobacter pylori in Western Australia
Background: The Australian Therapeutic Guidelines does not endorse culture and susceptibility testing prior to salvage therapy for Helicobacter pylorieradication. We wished to determine whether this remains appropriate.
Aim: To determine the sensitivity (as minimum inhibitory concentrations, MIC) of H pylorito a range of antibiotics used in salvage therapy over time.
Methods: From 2012 to 2017, gastric or duodenal biopsy samples were obtained from 154 patients receiving H pylorieradication therapy. MIC for amoxicillin, clarithromycin, tetracycline, metronidazole, rifampicin and levofloxacinwere measured using standard laboratory techniques.
Results: A significant increase from zero to 28% in secondary resistance to levofloxacin amongst H. pyloriin Western Australia was noted over the study period. No corresponding trend was seen with the other antibiotics.
Conclusions: These findings suggest that selective use of culture and susceptibility testing may be warranted prior to initiating salvage therapy with levofloxacin
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