COMORBIDITY BETWEEN FACTITIOUS AND BORDERLINE PERSONALITY DISORDER: A NARRATIVE ANALYSIS

Background: Factitious disorder (FD) illnesses have increased recently, primarily due to comorbidity with borderline personality disorder (BPD). Psychiatrists, hospital doctors, and general practitioners are interested in and concerned about patients with comorbid FD-BPD. Subjects and methods: We used a qualitative analysis of prototypical narratives collected as vignettes by merging individual contributions, case histories, naturalistic observations, and data from mental health practitioners into specific descriptions. Our study used a phenomenological and narrative method to illustrate the contents and behaviours in FD-BPD comorbidity. Results: Fourteen case vignettes were created from our case studies. These categories included knowledge of symptoms and medical terms, dramatisation, symptoms ambiguity, unexplainable deterioration of symptoms, symptom inventiveness, craving for painkillers, conflicts with health carers, hospital migration, piling of medication and search for invasive diagnostic procedures. Conclusions: The combined use of narrative analysis and naturalistic observation has helped identify a unique comorbid condition of FD-BPD, which is not yet clearly described in its behavioural components by the international literature. The current study presents novel findings into a condition becoming progressively popular in psychiatric and medical settings

PSYCHIATRY IN TIME OF COVID-19 PANDEMIC

COVID-19 or Coronavirus pandemic has generated a very serious and grave global concern regarding the health of every person in the whole world. Besides, due to the rapid diffusion of the viral infection, there are already alarms on how to deal with the psychiatric aspects of COVID-19 pandemic in persons with an established diagnosis of psychiatric disorders, staff, and those in selfisolation. What is the influence of COVID-19 on mental health? The current study will review the psychiatric implications of COVID-19 pandemic on the general population, the bearing of social isolation, the prevention behaviours, and clinical cases of people who required psychiatric admission to hospital due to the emotional impact of COVID-19 social circumstances

Social Network Analysis of Alzheimer’s Teams: A Clinical Review and Applications in Psychiatry to Explore Interprofessional Care

Understanding the social networks of professionals in psychiatric hospitals and communities working with persons with Alzheimer’s (PWA) disease helps tackle the knowledge management in patient care and the centrality of team members in providing information and advice to colleagues. To use Social Network Analysis (SNA) to confirm or reject the hypothesis that psychiatric professionals have equal status in sharing information and advice on the care of PWA and have reciprocal ties in a social network. The sample consisting of 50 psychiatric professionals working in geriatric psychiatry in the UK completed an anonymous online survey asking them to select the professional categories of the colleagues in the interprofessional team who are most frequently approached when providing or receiving advice about patient care and gathering patient information. SNA is both a descriptive qualitative analysis and a quantitative method that investigates the degree of the prestige of professionals in their working network, the reciprocity of their ties with other team members, and knowledge management. The social network graphs and numerical outcomes showed that interprofessional teams in geriatric psychiatry have health carers who play central roles in providing the whole team with the knowledge necessary for patient care; these are primarily senior professionals in nursing and medical roles. However, the study reported that only 13% of professionals had reciprocal ties with knowledge sharing within teams. The current research findings show that knowledge management in interprofessional teams caring for PWA is not evenly distributed. Those with apparently higher seniority and experience are more frequently consulted; however, other more peripheral figures can be equally valuable in integrated care.N/

Iron Dyshomeostasis in COVID-19: Biomarkers Reveal a Functional Link to 5-Lipoxygenase Activation

Coronavirus disease 2019 (COVID-19) is characterized by a broad spectrum of clinical symptoms. After acute infection, some subjects develop a post-COVID-19 syndrome known as long-COVID. This study aims to recognize the molecular and functional mechanisms that occur in COVID-19 and long-COVID patients and identify useful biomarkers for the management of patients with COVID-19 and long-COVID. Here, we profiled the response to COVID-19 by performing a proteomic analysis of lymphocytes isolated from patients. We identified significant changes in proteins involved in iron metabolism using different biochemical analyses, considering ceruloplasmin (Cp), transferrin (Tf), hemopexin (HPX), lipocalin 2 (LCN2), and superoxide dismutase 1 (SOD1). Moreover, our results show an activation of 5-lipoxygenase (5-LOX) in COVID-19 and in long-COVID possibly through an iron-dependent post-translational mechanism. Furthermore, this work defines leukotriene B4 (LTB4) and lipocalin 2 (LCN2) as possible markers of COVID-19 and long-COVID and suggests novel opportunities for prevention and treatment

Iron Dyshomeostasis in COVID-19: Biomarkers Reveal a Functional Link to 5-Lipoxygenase Activation

Coronavirus disease 2019 (COVID-19) is characterized by a broad spectrum of clinical symptoms. After acute infection, some subjects develop a post-COVID-19 syndrome known as longCOVID. This study aims to recognize the molecular and functional mechanisms that occur in COVID-19 and long-COVID patients and identify useful biomarkers for the management of patients with COVID-19 and long-COVID. Here, we profiled the response to COVID-19 by performing a proteomic analysis of lymphocytes isolated from patients. We identified significant changes in proteins involved in iron metabolism using different biochemical analyses, considering ceruloplasmin (Cp), transferrin (Tf), hemopexin (HPX), lipocalin 2 (LCN2), and superoxide dismutase 1 (SOD1). Moreover, our results show an activation of 5-lipoxygenase (5-LOX) in COVID19 and in long-COVID possibly through an iron-dependent post-translational mechanism. Furthermore, this work defines leukotriene B4 (LTB4) and lipocalin 2 (LCN2) as possible markers of COVID-19 and long-COVID and suggests novel opportunities for prevention and treatment