2020-05-08 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: UNM drug repurposing. NM cases. Doctors Without Borders. SNAP benefits online. NM 7th highest unemployment. Virtual LemonAid tonight. New N98 masks. Healthcare supply chain challenge. EMS lack resources. Infection risk in healthcare workers. COVID-19 on medical education. Human disinfectant chambers. Evidence of seroconversion. Dangers of considering herd immunity. Wastewater-based surveillance. More youths infected. Reconstructing ship spread. Pharmacoepidemiologic analysis. Clinicopathologic characteristics. Cancer treatment impact. Reduced voluntary psychiatric admission in Italy. Operating room management. Humidifiers reduce transmission. Phone contact tracing ethics. Call for patient database. Immunity certification program. Guidelines on tracheostomy, IBD, nose bleeding, pituitary tumors, and hematopoietic stem cells transplantation, benefits of low-PEEP, and of molecular diagnostics. FDA authorizes at-home test. Cephid Xpert test. MRSA nasal swabs. NIH remdesivir+barictinib RCT. Corticosteroid caution. Arbidol active in vitro. ACE/ARB systematic review. In silico phytochemical and virus protease candidates. Potential zinc benefit. 31 new clinical trials. Glycemic control benefit. Psychological effects meta-analysis and survey. Disease course model. Liver injury. Environmental and health perspectives. Olfactory and gustatory dysfunction. Vitamin D. Disease map

2020-04-30 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM residential facility deaths. NM case update. NM TriCore testing antibodies. Navajo nation cases. May 10 Navajo peak. Udall funding push. El Paso shopping discouraged. NM budget shortfall. Santa Fe furlough. Ethanol sanitizer safety. LA free testing for all. Michigan protest. NM Batelle N95 decontamination. Hospital revenue decline. Wastewater early detection. German herd immunity. 60-day viral shedding possible. Temporary infected “ark”. Prison release preparedness. Low quality research. Phased long-term care. Suicide prevention. Corticosteroid tradeoffs. Cloth mask guidelines. SARS-CoV-2 assays compared. IgG and viral loads. Better testing reporting. Dubious testing vendors. Promising oral drug. Hydroxychloroquine prophylaxis dosing. Umifenovir ineffective. Multi-drug nanoparticles. Drug discovery new targets. 38 new COVID-19 trials. Cancer research review. Attenuated SARS-CoV-2

2020-05-05 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM cases. Navajo cases. NM remdesivir inaccessible. Infected prison staff. No early prison releases. Unemployment beats working. NM $97M food benefits. UNM$50M revenue loss. Meat packer testing. Fall school reopening planning. Gym/salon reopening plans. 91k absentee ballots. Santa Fe closes polling stations. NM oil/gas pollution oversight. Prisons vulnerable. WH rejects FEMA report. Schools plan reopening. Italian mafia concerns. UK overtakes Italy. Symptom tracker early warning. Ethanol for FFP2 masks. Counterfeit masks. Mask skin damage. Mutant coronavirus more contagious. Hospital contamination zones. Disease prevalence estimation. Successful control measures. Average contagious period. Genetic epidemiology. Managing healthcare resources. Exercise and fitness. Italian disease management Q&A. Practice guidelines on: bronchoscopy, sarcoidosis management, glycemic control, key laboratory tests, ACE/ARB Tx, neurosurgery, cardiac surgery. WHO: test old pneumonia samples. SW NM free testing. Diagnostic assays compared. Corticosteroid benefits. Beekeepers COVID-free? European vaccine US trials. Cytokine storm interventions. Lopinavir-ritonavir second chance. Melatonin potential Tx. 48 clinical trials. Placental infection. Cytokine severity markers. Male lungs worse. Sleep problems. IBD physician survey. Researcher career impact

2020-05-14 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM restrictions loosen. NM case count. Navajo Nation case count. 9 state parks open. Sunport revenue loss. Trump projects vaccine delivery. Wisconsin court case. Smokers quit. Ireland reopening. Danish schools open. Philippine typhoon evacuation. PPE-induced pressure injuries and facial dermatoses. U.S. mask stockpile. PPE for surgeons. Intubation time with aerosol box. Consumer spending with social restrictions. Suicide increase expected. Undetected virus homeless. Chinese infection control. 5% Spain infected. Sanitizing booth. Healthcare worker infection routes. Kawasaki disease France. CDC Kawaski guidance. Italian deaths characterized. CDC reopening school guidance. COVID-19 and epistemology. Monitoring misleading claims. UN mental health policy brief. CDC vaccination schedules. Guidelines on managing endoscopy units. COVID-19 lab testing (for lab professionals). Cancer surgery triage. Operating room practices. Orthodontic treatment. 3D printed NP swabs effective. Salt-water irrigation reduces duration. Corticosteroids ineffectual. Vaccines require biomanufacturing infrastructure. French pharm giant promises fair vaccine distribution. 26 new trials registered. LDH, lymphocytes and hs-CRP predict mortality. Fibrinogen higher in SARS. Insulin resistance. Glycemic monitoring. Hemostasis abnormalities. New phobia scale. OR global consensus. Inpatient cognitive assessments are challenging. Loud speech increases transmission. Monkeys present similarly. Human-to-dog transmission. Cat transmission

2020-05-09/10 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM gets remdesivir. NM case update. Dental services resume. NM prison testing. Educator age risk. Stuart Kauffman dashboard. Long-term care fatalities. Fauci in quarantine. US farmer support. US vaccinations down. South Korea bar shutdown. German rebound lockdown easing. Managing glove skin reactions. Neurosurgery down 70%. Impact airline travel ban. CDC meat packing report. UK distancing impact. 9-day incubation. Low fatality rate estimates. Improving social connection. Social distancing and mask use effective. Parents under stress. Nurse psychological stress. Israel Internal Medicine Tx strategies. Education management. Recommendations are given on endoscopy procedures, management of adrenal insufficiency and of IBD, on re-introduction of cardiovascular services, and respiratory PPE for healthcare workers. Guidelines for medical examiners, coroners, and pathologists. Successful GI department re-opening in China. FDA: serology testing performance. First antigen test approved. FFPE SARS-CoV-2 detection. Triple antiviral therapy effective. Respiratory rehabilitation effective. Targeting inflammatory cascade. Negative HCQ observational study. Chloroquine G6PD risk. Interferon inhibits replication – mouse. Tocilizumab benefit: uncontrolled study. Most trials in HCQ, remdesivir. NKG2A treatment target. In silico antiviral peptides. Chinese medicine review. Cell entry mechanisms. Olfactory viral entry. Higher female immune response. Immune checkpoints. Metagenomic analysis. ¼ hospitalized no risk factors. High RDW mortality. Mortality: vitamin D. Deaths of despair. Optimism and exercise

2020-05-20 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING

Executive Summary: NM Highlights: Governor’s update. NM case count. Governor’s response to republicans. Western Sky Community donation. Santa Feans using face coverings. NM Medicaid enrollment. NM colleges fall reopening. Rio Rancho partial reopening. NM Tourism Department cooking recipes. ABQ Meals on Wheels feeding more. US Highlights: Mexico influx California hospitals. Arkansas church outbreak. International Highlights: Estonia immunity passport rollout. South Korea school reopenings. Economics, Workforce, Supply Chain, PPE Highlights: Hydrogel patches for pressure injuries. Resuscitation with PPE. Journal of wound care PPE guidelines. Food supply chain protections. Epidemiology Highlights: Higher rates in Black communities. Superspreaders may explain propagation patterns. “Back-projection” used for analysis. Healthcare Policy Recommendations: Systems analysis of pandemic management is performed. Policy recommendations based on a nationwide psychological China survey. Practice Guidelines: COPD management FAQ and patient support resources. Testing: CRISPR rapid test. Fast and simple single tube assay. Drugs, Vaccines, Therapies, Clinical Trials: Protective immunity in macaques. DNA vaccine. Lopinavir and Ritonavir pharmacokinetics. 32 new trials. Other science: ACEI/ARB and disease severity. Cold plasma. Survey call for clinicians