385 research outputs found

    Conventions spreading in open-ended systems

    Full text link
    We introduce a simple open-ended model that describes the emergence of a shared vocabulary. The ordering transition toward consensus is generated only by an agreement mechanism. This interaction defines a finite and small number of states, despite each individual having the ability to invent an unlimited number of new words. The existence of a phase transition is studied by analyzing the convergence times, the cognitive efforts of the agents and the scaling behavior in memory and timeComment: 11 pages, 5 figure

    Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease

    Get PDF
    AIMS Arterial spin labelling (ASL) MRI measures perfusion without administration of contrast agent. While ASL has been validated in animals and healthy volunteers (HVs), application to chronic kidney disease (CKD) has been limited. We investigated the utility of ASL MRI in patients with CKD. METHODS We studied renal perfusion in 24 HVs and 17 patients with CKD (age 22-77 years, 40% male) using ASL MRI at 3.0T. Kidney function was determined using estimated glomerular filtration rate (eGFR). T1 relaxation time was measured using modified look-locker inversion and xFB02;ow-sensitive alternating inversion recovery true-fast imaging and steady precession was performed to measure cortical and whole kidney perfusion. RESULTS T1 was higher in CKD within cortex and whole kidney, and there was association between T1 time and eGFR. No association was seen between kidney size and volume and either T1, or ASL perfusion. Perfusion was lower in CKD in cortex (136 ± 37 vs. 279 ± 69 ml/min/100 g; p < 0.001) and whole kidney (146 ± 24 vs. 221 ± 38 ml/min/100 g; p < 0.001). There was significant, negative, association between T1 longitudinal relaxation time and ASL perfusion in both the cortex (r = -0.75, p < 0.001) and whole kidney (r = -0.50, p < 0.001). There was correlation between eGFR and both cortical (r = 0.73, p < 0.01) and whole kidney (r = 0.69, p < 0.01) perfusion. CONCLUSIONS Significant differences in renal structure and function were demonstrated using ASL MRI. T1 may be representative of structural changes associated with CKD; however, further investigation is required into the pathological correlates of reduced ASL perfusion and increased T1 time in CKD

    Bethe ansatz solution of the anisotropic correlated electron model associated with the Temperley-Lieb algebra

    Full text link
    A recently proposed strongly correlated electron system associated with the Temperley-Lieb algebra is solved by means of the coordinate Bethe ansatz for periodic and closed boundary conditions.Comment: 21 page

    Bethe ansatz solution of the closed anisotropic supersymmetric U model with quantum supersymmetry

    Full text link
    The nested algebraic Bethe ansatz is presented for the anisotropic supersymmetric UU model maintaining quantum supersymmetry. The Bethe ansatz equations of the model are obtained on a one-dimensional closed lattice and an expression for the energy is given.Comment: 7 pages (revtex), minor modifications. To appear in Mod. Phys. Lett.

    Research priorities in cardiovascular imaging.

    Get PDF
    AIM: A modified Delphi approach was used to develop consensus opinion among British Society for Cardiac Imaging/British Society of Cardiac CT (BSCI/BSCCT) members in order to prioritise research questions in cardiovascular imaging. METHODS: All members of the BSCI/BSCCT were invited to submit research questions that they considered to be of the highest clinical and/or academic priority in the field of cardiovascular imaging (phase 1). Subsequently a steering committee removed duplicate questions and combined questions of a similar theme by consensus agreement where appropriate. BSCI/BSCCT members were invited to rank the resulting research questions in two further iterative rounds (phases 2 and 3) to determine a final list of high-priority research questions. RESULTS: A total of 111 research questions were submitted in phase 1 by 30 BSCI/BSCCT members. While there was a broad range of topics, from determining the optimal features/markers of the vulnerable plaque to investigating how cardiac imaging can best be used to maximise clinical outcomes and economic costs, multimodality imaging-related (n=44, 40%) questions dominated the categories and coronary artery imaging (n=40, 36%) was the most common topic. Over two iterative rounds of prioritisation of these research questions, the original 111 were reduced to 75 questions in round 2, and 25 in round 3. From these 25 a final Top 10 list was distilled by consensus grouping. CONCLUSION: This study has identified and ranked the top research priorities in cardiovascular imaging, as identified by the BSCI/BSCCT membership. This is a first step towards identifying the cardiovascular imaging research priorities within the UK and may assist researchers and funding bodies alike in setting priorities

    Gaussian Wavefunctional Approach in Thermofield Dynamics

    Full text link
    The Gaussian wavefunctional approach is developed in thermofield dynamics. We manufacture thermal vacuum wavefunctional, its creation as well as annihilation operators,and accordingly thermo-particle excited states. For a (D+1)-dimensional scalar field system with an arbitrary potential whose Fourier representation exists in a sense of tempered distributions, we calculate the finite temperature Gaussian effective potential (FTGEP), one- and two-thermo-particle-state energies. The zero-temperature limit of each of them is just the corresponding result in quantum field theory, and the FTGEP can lead to the same one of each of some concrete models as calculated by the imaginary time Green function.Comment: the revised version of hep-th/9807025, with one equation being added, a few sentences rewritten, and some spelling mistakes corrected. 7 page, Revtex, no figur

    Integrable multiparametric quantum spin chains

    Full text link
    Using Reshetikhin's construction for multiparametric quantum algebras we obtain the associated multiparametric quantum spin chains. We show that under certain restrictions these models can be mapped to quantum spin chains with twisted boundary conditions. We illustrate how this general formalism applies to construct multiparametric versions of the supersymmetric t-J and U models.Comment: 17 pages, RevTe

    Thermal and magnetic properties of integrable spin-1 and spin-3/2 chains with applications to real compounds

    Full text link
    The ground state and thermodynamic properties of spin-1 and spin-3/2 chains are investigated via exactly solved su(3) and su(4) models with physically motivated chemical potential terms. The analysis involves the Thermodynamic Bethe Ansatz and the High Temperature Expansion (HTE) methods. For the spin-1 chain with large single-ion anisotropy, a gapped phase occurs which is significantly different from the valence-bond-solid Haldane phase. The theoretical curves for the magnetization, susceptibility and specific heat are favourably compared with experimental data for a number of spin-1 chain compounds. For the spin-3/2 chain a degenerate gapped phase exists starting at zero external magnetic field. A middle magnetization plateau can be triggered by the single-ion anisotropy term. Overall, our results lend further weight to the applicability of integrable models to the physics of low-dimensional quantum spin systems. They also highlight the utility of the exact HTE method.Comment: 38 pages, 15 figure

    Cytochrome oxidase subunit VI of Trypanosoma brucei is imported without a cleaved presequence and is developmentally regulated at both RNA and protein levels

    Get PDF
    Mitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these parasites. As a model for understanding the co-ordination of these genomes, we have examined the regulation and mitochondrial import of a nuclear-encoded component of the cytochrome oxidase complex, cytochrome oxidase subunit VI (COXVI). By generating transgenic trypanosomes expressing intact or mutant forms of this protein, we demonstrate that COXVI is not imported using a conventional cleaved presequence and show that sequences at the N-terminus of the protein are necessary for correct mitochondrial sorting. Analyses of endogenous and transgenic COXVI mRNA and protein expression in parasites undergoing developmental stage differentiation demonstrates a temporal order of control involving regulation in the abundance of, first, mRNA and then protein. This represents the first dissection of the regulation and import of a nuclear-encoded protein into the cytochrome oxidase complex in these organisms, which were among the earliest eukaryotes to possess a mitochondrion
    • …
    corecore