1,838 research outputs found
The Impact of Patient and Provider Education on Statin Therapy Initiation and Adherence in Type II Diabetics
Purpose/Background
Type 2 diabetes mellitus (T2DM) is a common, chronic disease that increases the risk of coronary artery disease and stroke fourfold, which makes protecting cardiac function a priority. The American Diabetes Association (ADA) and American Heart Association (AHA) recommend the prescription of statins to reduce cardiovascular complications. Unfortunately, provider and patient adherence to this recommendation is poor.This study aimed to determine if shared-decision making and patient follow-up within a 6 month period of being newly diagnosed with T2D has an effect on the initiation rate of statin therapy.
Methods
In this retrospective study we requested data from the University of Tennessee Family Medicine clinic on newly diagnosed diabetic patients from December 2021 to December 2023 that met criteria (40 years or older, eligible for statin therapy, new diagnosis of T2D, had at least one follow-up appointment within the last 2 years). Information requested included the patient’s sex, age, baseline HbA1C, referral date, and whether or not statin therapy was initiated within 6 months of diagnosis. The data was then analyzed for descriptive statistics using Intellectus statistical analysis software.
Results
Twenty-nine patients (8 male, 21 female) met inclusion criteria. The mean age of the participants was 52.8 years (female mean age: 54.9 years; male mean age: 47.5 years), and the mean baseline HgA1C was 9.16%. Of the 29 patients included in the study, 100% of them had statin therapy initiated within 6 months of diagnosis.
Implications for Nursing Practice
The results of this study are reassuring that patient follow up within 6 months of a new T2D diagnosis is key in initiating current statin therapy guidelines. These findings reinforce the essential role of nurse practitioners in the management of T2D and associated cardiovascular risk, highlighting the importance of patient education, regular monitoring, and collaborative care
The effectiveness of Sufi music for mental health outcomes. A systematic review and meta-analysis of 21 randomised trials.
BACKGROUND: There is some evidence that Sufi music therapy might improve physical and mental well-being; however, no systematic review or meta-analysis has pooled and critiqued the evidence. The aim of this systematic review was to evaluate the effects of Sufi music therapy on mental health outcomes. METHODS: We searched Medline, PsycINFO, the Web of Science, Science Direct, PsycARTICLES, Cochrane Library, SCOPUS, CINAHL Plus, AMED, and ULAKBIM databases, and the reference lists of the studies found. Papers published in academic peer-reviewed journals were included, as well as from other sources such as chapters in edited books, the grey literature, or conference presentations. Articles published up to March 2020 in Turkish and English were included. Our primary outcome of interest was anxiety and secondary outcomes of interest were other mental health outcomes such as depression. To assess the methodological quality of the articles, the Cochrane Risk of Bias Tool was used. The quality of evidence was assessed using the GRADEpro GDT system. RESULTS: This search yielded 21 clinical trials that were eligible for inclusion. A meta-analysis, using a random effects model, of 18 randomised controlled trials involving 1454 participants showed that Sufi music therapy with makams, compared with treatment as usual (TAU) or a no-music control group, reduced symptoms of anxiety in the short term in patients undergoing an operation or treatments such as chemotherapy or haemodialysis (standardised mean difference SMD= -1.15, 95% CI, -1.64 to -0.65; very low-quality evidence). The evidence of Sufi music with makam's effect on anxiety is rated as very low. Qualitative synthesis of secondary outcomes revealed significant effects for depression, positive symptoms in schizophrenia, stress, which however were based on fewer studies. Trials were of moderate methodological quality, and there was significant heterogeneity across the studies. CONCLUSION: Sufi music may reduce anxiety of patients undergoing medical procedures like haemodialysis, coronary artery surgery, angiography, colonoscopy, bone marrow aspiration and biopsy procedures. Evidence from single studies suggests effects on depression and stress as well. However, due to methodological limitations of the studies, further, higher quality studies are required in other cultures
Constrained analytical interrelations in neutrino mixing
Hermitian squared mass matrices of charged leptons and light neutrinos in the
flavor basis are studied under general additive lowest order perturbations away
from the tribimaximal (TBM) limit in which a weak basis with mass diagonal
charged leptons is chosen. Simple analytical expressions are found for the
three measurable TBM-deviants in terms of perturbation parameters appearing in
the neutrino and charged lepton eigenstates in the flavor basis. Taking
unnatural cancellations to be absent and charged lepton perturbation parameters
to be small, interrelations are derived among masses, mixing angles and the
amount of CP-violation.Comment: To be published in the Springer Proceedings in the Physics Series
under the heading of the XXI DAE-BRNS Symposium (Guwahati, India
An SO(10) Grand Unified Theory of Flavor
We present a supersymmetric SO(10) grand unified theory (GUT) of flavor based
on an family symmetry. It makes use of our recent proposal to use SO(10)
with type II seesaw mechanism for neutrino masses combined with a simple ansatz
that the dominant Yukawa matrix (the {\bf 10}-Higgs coupling to matter) has
rank one. In this paper, we show how the rank one model can arise within some
plausible assumptions as an effective field theory from vectorlike {\bf 16}
dimensional matter fields with masses above the GUT scale. In order to obtain
the desired fermion flavor texture we use flavon multiplets which acquire
vevs in the ground state of the theory. By supplementing the theory with
an additional discrete symmetry, we find that the flavon vacuum field
alignments take a discrete set of values provided some of the higher
dimensional couplings are small. Choosing a particular set of these vacuum
alignments appears to lead to an unified understanding of observed quark-lepton
flavor:
(i) the lepton mixing matrix that is dominantly tri-bi-maximal with small
corrections related to quark mixings; (ii) quark lepton mass relations at GUT
scale: and and (iii) the solar to
atmospheric neutrino mass ratio in agreement with observations. The model predicts the neutrino
mixing parameter, ,
which should be observable in planned long baseline experiments.Comment: Final version of the paper as it will appear in JHEP
Using foresight futures and systems thinking to evaluate digitally enhanced advanced service concepts for a rolling stock company (ROSCO)
Purpose: This paper reports on a study in conjunction with a UK-based rolling stock leasing company (ROSCO). The aim was to generate and evaluate future operational concepts for digitally enhanced advanced services from the point of view of a ROSCO – one of many stakeholders (or actors) within a future wider mobility ecosystem.Design/Methodology/Approach: The research design followed the Generic Foresight Process Framework (Voros 2003). Desk-based research and horizon scanning analysis revealed technologies, mobility and transport trends, and other predictions towards 2060. A workshop was developed and participants were presented with a series of future scenarios and design fictions for end-to-end intermodal mobility and passenger carbon quotas. A future Mobility Servitization Systems Architecture was developed.Findings: Five future megatrends were identified; Decarbonisation, changing traveller needs, digitisation, mobility ecosystems and new business models in digital ecosystems. The ‘what-if’ activities revealed insights into alternate futures; revealing system of systems (SoS) actors, the role of a ROSCO, integrations, assumptions and operational constraints.Originality/Value: This research contributes to engineering and design methods for digitally enhanced advanced services, particularly for corporate strategic foresight in a dominant design industry. The Mobility Servitization Systems Architecture was seen to be a powerful model for ecosystem understanding.</div
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